HNRPAB: Difference between revisions

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Revision as of 13:58, 31 August 2017

Heterogeneous nuclear ribonucleoprotein A/B, also known as HNRPAB, is a protein which in humans is encoded by the HNRPAB gene.^[1] Although this gene is named HNRNPAB in reference to its first cloning as an RNA binding protein with similarity to HNRNP A and HNRNP B,^[2] it is not a member of the HNRNP A/B subfamily of HNRNPs, but groups together closely with HNRNPD/AUF1 and HNRNPDL.^[3]^[4]

Function

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are produced by RNA polymerase II and are components of the heterogeneous nuclear RNA (hnRNA) complexes. They are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene, which binds to one of the components of the multiprotein editosome complex, has two repeats of quasi-RRM (RNA recognition motif) domains that bind to RNAs. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.^[1]

Interactions

HNRPAB has been shown to interact with TP63.^[5]

References

↑ ^1.0 ^1.1 "Entrez Gene: HNRPAB heterogeneous nuclear ribonucleoprotein A/B".
↑ Khan FA, Jaiswal AK, Szer W (September 1991). "Cloning and sequence analysis of a human type A/B hnRNP protein". FEBS Lett. 290 (1–2): 159–61. doi:10.1016/0014-5793(91)81249-8. PMID 1717314.
↑ Akindahunsi AA, Bandiera A, Manzini G (February 2005). "Vertebrate 2xRBD hnRNP proteins: a comparative analysis of genome, mRNA and protein sequences". Comput Biol Chem. 29 (1): 13–23. doi:10.1016/j.compbiolchem.2004.11.002. PMID 15680582.
↑ Czaplinski K, Köcher T, Schelder M, Segref A, Wilm M, Mattaj IW (April 2005). "Identification of 40LoVe, a Xenopus hnRNP D family protein involved in localizing a TGF-beta-related mRNA during oogenesis". Dev. Cell. 8 (4): 505–15. doi:10.1016/j.devcel.2005.01.012. PMID 15809033.
↑ Fomenkov, Alexey; Huang Yi-Ping; Topaloglu Ozlem; Brechman Anna; Osada Motonobo; Fomenkova Tanya; Yuriditsky Eugene; Trink Barry; Sidransky David; Ratovitski Edward (Jun 2003). "P63 alpha mutations lead to aberrant splicing of keratinocyte growth factor receptor in the Hay-Wells syndrome". J. Biol. Chem. United States. 278 (26): 23906–14. doi:10.1074/jbc.M300746200. ISSN 0021-9258. PMID 12692135.

Khan FA, Jaiswal AK, Szer W (1991). "Cloning and sequence analysis of a human type A/B hnRNP protein". FEBS Lett. 290 (1–2): 159–61. doi:10.1016/0014-5793(91)81249-8. PMID 1717314.
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Gress TM, Müller-Pillasch F, Geng M, et al. (1996). "A pancreatic cancer-specific expression profile". Oncogene. 13 (8): 1819–30. PMID 8895530.
Lau PP, Zhu HJ, Nakamuta M, Chan L (1997). "Cloning of an Apobec-1-binding protein that also interacts with apolipoprotein B mRNA and evidence for its involvement in RNA editing". J. Biol. Chem. 272 (3): 1452–5. doi:10.1074/jbc.272.3.1452. PMID 8999813.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Hay DC, Kemp GD, Dargemont C, Hay RT (2001). "Interaction between hnRNPA1 and IkappaBalpha is required for maximal activation of NF-kappaB-dependent transcription". Mol. Cell. Biol. 21 (10): 3482–90. doi:10.1128/MCB.21.10.3482-3490.2001. PMC 100270. PMID 11313474.
Lau PP, Chang BH, Chan L (2001). "Two-hybrid cloning identifies an RNA-binding protein, GRY-RBP, as a component of apobec-1 editosome". Biochem. Biophys. Res. Commun. 282 (4): 977–83. doi:10.1006/bbrc.2001.4679. PMID 11352648.
Gallouzi IE, Brennan CM, Steitz JA (2001). "Protein ligands mediate the CRM1-dependent export of HuR in response to heat shock". RNA. 7 (9): 1348–61. doi:10.1017/S1355838201016089. PMC 1370177. PMID 11565755. (Retracted. If this is an intentional citation to a retracted paper, please replace {{Retracted}} with {{Retracted|intentional=yes}}.)
Andersen JS, Lyon CE, Fox AH, et al. (2002). "Directed proteomic analysis of the human nucleolus". Curr. Biol. 12 (1): 1–11. doi:10.1016/S0960-9822(01)00650-9. PMID 11790298.
Percipalle P, Jonsson A, Nashchekin D, et al. (2002). "Nuclear actin is associated with a specific subset of hnRNP A/B-type proteins". Nucleic Acids Res. 30 (8): 1725–34. doi:10.1093/nar/30.8.1725. PMC 113215. PMID 11937625.
Angenstein F, Evans AM, Settlage RE, et al. (2002). "A receptor for activated C kinase is part of messenger ribonucleoprotein complexes associated with polyA-mRNAs in neurons". J. Neurosci. 22 (20): 8827–37. PMID 12388589.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Fomenkov A, Huang YP, Topaloglu O, et al. (2003). "P63 alpha mutations lead to aberrant splicing of keratinocyte growth factor receptor in the Hay-Wells syndrome". J. Biol. Chem. 278 (26): 23906–14. doi:10.1074/jbc.M300746200. PMID 12692135.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Zhang S, Schlott B, Görlach M, Grosse F (2004). "DNA-dependent protein kinase (DNA-PK) phosphorylates nuclear DNA helicase II/RNA helicase A and hnRNP proteins in an RNA-dependent manner". Nucleic Acids Res. 32 (1): 1–10. doi:10.1093/nar/gkg933. PMC 373260. PMID 14704337.
Gao C, Guo H, Wei J, et al. (2004). "S-nitrosylation of heterogeneous nuclear ribonucleoprotein A/B regulates osteopontin transcription in endotoxin-stimulated murine macrophages". J. Biol. Chem. 279 (12): 11236–43. doi:10.1074/jbc.M313385200. PMID 14722087.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Ong SE, Mittler G, Mann M (2005). "Identifying and quantifying in vivo methylation sites by heavy methyl SILAC". Nat. Methods. 1 (2): 119–26. doi:10.1038/nmeth715. PMID 15782174.
Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243.
Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.

This article on a gene on human chromosome 5 is a stub. You can help Wikipedia by expanding it.

[entrez-1] 1.0 ^1.1 "Entrez Gene: HNRPAB heterogeneous nuclear ribonucleoprotein A/B".

[pmid1717314-2] Khan FA, Jaiswal AK, Szer W (September 1991). "Cloning and sequence analysis of a human type A/B hnRNP protein". FEBS Lett. 290 (1–2): 159–61. doi:10.1016/0014-5793(91)81249-8. PMID 1717314.

[pmid15680582-3] Akindahunsi AA, Bandiera A, Manzini G (February 2005). "Vertebrate 2xRBD hnRNP proteins: a comparative analysis of genome, mRNA and protein sequences". Comput Biol Chem. 29 (1): 13–23. doi:10.1016/j.compbiolchem.2004.11.002. PMID 15680582.

[pmid15809033-4] Czaplinski K, Köcher T, Schelder M, Segref A, Wilm M, Mattaj IW (April 2005). "Identification of 40LoVe, a Xenopus hnRNP D family protein involved in localizing a TGF-beta-related mRNA during oogenesis". Dev. Cell. 8 (4): 505–15. doi:10.1016/j.devcel.2005.01.012. PMID 15809033.

[pmid12692135-5] Fomenkov, Alexey; Huang Yi-Ping; Topaloglu Ozlem; Brechman Anna; Osada Motonobo; Fomenkova Tanya; Yuriditsky Eugene; Trink Barry; Sidransky David; Ratovitski Edward (Jun 2003). "P63 alpha mutations lead to aberrant splicing of keratinocyte growth factor receptor in the Hay-Wells syndrome". J. Biol. Chem. United States. 278 (26): 23906–14. doi:10.1074/jbc.M300746200. ISSN 0021-9258. PMID 12692135.

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[2]

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[4]

[5]

@@ Line 1: / Line 1: @@
-<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
+{{Infobox_gene}}
-{{PBB_Controls
+'''Heterogeneous nuclear ribonucleoprotein A/B''', also known as '''HNRPAB''', is a protein which in humans is encoded by the ''HNRPAB'' [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: HNRPAB heterogeneous nuclear ribonucleoprotein A/B| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3182| accessdate = }}</ref> Although this gene is named ''HNRNPAB'' in reference to its first cloning as an RNA binding protein with similarity to [[HNRNPA0|HNRNP A]] and HNRNP B,<ref name="pmid1717314">{{cite journal |vauthors=Khan FA, Jaiswal AK, Szer W | title = Cloning and sequence analysis of a human type A/B hnRNP protein | journal = FEBS Lett. | volume = 290 | issue = 1-2 | pages = 159–61 |date=September 1991 | pmid = 1717314 | doi = 10.1016/0014-5793(91)81249-8  | url =   }}</ref> it is not a member of the HNRNP A/B subfamily of [[heterogeneous ribonucleoprotein particle|HNRNPs]], but groups together closely with HNRNPD/AUF1 and HNRNPDL.<ref name="pmid15680582">{{cite journal |vauthors=Akindahunsi AA, Bandiera A, Manzini G | title = Vertebrate 2xRBD hnRNP proteins: a comparative analysis of genome, mRNA and protein sequences | journal = Comput Biol Chem | volume = 29 | issue = 1 | pages = 13–23 |date=February 2005 | pmid = 15680582 | doi = 10.1016/j.compbiolchem.2004.11.002 | url =  }}</ref><ref name="pmid15809033">{{cite journal |vauthors=Czaplinski K, Köcher T, Schelder M, Segref A, Wilm M, Mattaj IW | title = Identification of 40LoVe, a Xenopus hnRNP D family protein involved in localizing a TGF-beta-related mRNA during oogenesis | journal = Dev. Cell | volume = 8 | issue = 4 | pages = 505–15 |date=April 2005 | pmid = 15809033 | doi = 10.1016/j.devcel.2005.01.012 | url =  }}</ref>
-| update_page = yes
-| require_manual_inspection = no
-| update_protein_box = yes
-| update_summary = yes
-| update_citations = yes
-}}
-<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
+==Function==
-{{GNF_Protein_box
+This gene belongs to the subfamily of ubiquitously expressed [[heterogeneous ribonucleoprotein particle|heterogeneous nuclear ribonucleoproteins]] (hnRNPs). The hnRNPs are produced by [[RNA polymerase II]] and are components of the heterogeneous nuclear RNA (hnRNA) complexes. They are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the [[cell nucleus|nucleus]] and the [[cytoplasm]]. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene, which binds to one of the components of the multiprotein editosome complex, has two repeats of quasi-RRM (RNA recognition motif) domains that bind to RNAs. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.<ref name="entrez"/>
- | image =
- | image_source =
- | PDB =
- | Name = Heterogeneous nuclear ribonucleoprotein A/B
- | HGNCid = 5034
- | Symbol = HNRPAB
- | AltSymbols =; ABBP1
- | OMIM = 602688
- | ECnumber =
- | Homologene = 74950
- | MGIid = 1330294
- | GeneAtlas_image1 = PBB_GE_HNRPAB_201277_s_at_tn.png
- | Function = {{GNF_GO|id=GO:0000166 |text = nucleotide binding}} {{GNF_GO|id=GO:0003724 |text = RNA helicase activity}} {{GNF_GO|id=GO:0003729 |text = mRNA binding}}
- | Component = {{GNF_GO|id=GO:0005634 |text = nucleus}}
- | Process = {{GNF_GO|id=GO:0006381 |text = mRNA editing}}
- | Orthologs = {{GNF_Ortholog_box
-    | Hs_EntrezGene = 3182
-    | Hs_Ensembl = ENSG00000197451
-    | Hs_RefseqProtein = NP_004490
-    | Hs_RefseqmRNA = NM_004499
-    | Hs_GenLoc_db =
-    | Hs_GenLoc_chr = 5
-    | Hs_GenLoc_start = 177564114
-    | Hs_GenLoc_end = 177570787
-    | Hs_Uniprot = Q99729
-    | Mm_EntrezGene = 15384
-    | Mm_Ensembl = ENSMUSG00000020358
-    | Mm_RefseqmRNA = NM_010448
-    | Mm_RefseqProtein = NP_034578
-    | Mm_GenLoc_db =
-    | Mm_GenLoc_chr = 11
-    | Mm_GenLoc_start = 51443523
-    | Mm_GenLoc_end = 51450270
-    | Mm_Uniprot = Q544Z3
-  }}
-}}
-'''Heterogeneous nuclear ribonucleoprotein A/B''', also known as '''HNRPAB''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: HNRPAB heterogeneous nuclear ribonucleoprotein A/B| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3182| accessdate = }}</ref>
-<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
+==Interactions==
-{{PBB_Summary
+HNRPAB has been shown to [[Protein-protein interaction|interact]] with [[TP63]].<ref name=pmid12692135>{{cite journal |last=Fomenkov |first=Alexey |authorlink= |author2=Huang Yi-Ping |author3=Topaloglu Ozlem |author4=Brechman Anna |author5=Osada Motonobo |author6=Fomenkova Tanya |author7=Yuriditsky Eugene |author8=Trink Barry |author9=Sidransky David |author10=Ratovitski Edward  |date=Jun 2003 |title=P63 alpha mutations lead to aberrant splicing of keratinocyte growth factor receptor in the Hay-Wells syndrome |journal=J. Biol. Chem. |volume=278 |issue=26 |pages=23906–14 |publisher= |location = United States| issn = 0021-9258| pmid = 12692135 |doi = 10.1074/jbc.M300746200 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref>
-| section_title =
-| summary_text = This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are produced by RNA polymerase II and are components of the heterogeneous nuclear RNA (hnRNA) complexes. They are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene, which binds to one of the components of the multiprotein editosome complex, has two repeats of quasi-RRM (RNA recognition motif) domains that bind to RNAs. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.<ref name="entrez">{{cite web | title = Entrez Gene: HNRPAB heterogeneous nuclear ribonucleoprotein A/B| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3182| accessdate = }}</ref>
-}}
 ==References==
-{{reflist|2}}
+{{Reflist}}
 ==Further reading==
 {{refbegin | 2}}
 {{PBB_Further_reading
 | citations =
-*{{cite journal  | author=Khan FA, Jaiswal AK, Szer W |title=Cloning and sequence analysis of a human type A/B hnRNP protein. |journal=FEBS Lett. |volume=290 |issue= 1-2 |pages= 159-61 |year= 1991 |pmid= 1717314 |doi=  }}
+*{{cite journal  |vauthors=Khan FA, Jaiswal AK, Szer W |title=Cloning and sequence analysis of a human type A/B hnRNP protein. |journal=FEBS Lett. |volume=290 |issue= 1-2 |pages= 159–61 |year= 1991 |pmid= 1717314 |doi=10.1016/0014-5793(91)81249-8  }}
-*{{cite journal  | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171-4 |year= 1994 |pmid= 8125298 |doi=  }}
+*{{cite journal  |vauthors=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=10.1016/0378-1119(94)90802-8  }}
-*{{cite journal  | author=Gress TM, Müller-Pillasch F, Geng M, ''et al.'' |title=A pancreatic cancer-specific expression profile. |journal=Oncogene |volume=13 |issue= 8 |pages= 1819-30 |year= 1996 |pmid= 8895530 |doi=  }}
+*{{cite journal   |vauthors=Gress TM, Müller-Pillasch F, Geng M, etal |title=A pancreatic cancer-specific expression profile. |journal=Oncogene |volume=13 |issue= 8 |pages= 1819–30 |year= 1996 |pmid= 8895530 |doi=  }}
-*{{cite journal  | author=Lau PP, Zhu HJ, Nakamuta M, Chan L |title=Cloning of an Apobec-1-binding protein that also interacts with apolipoprotein B mRNA and evidence for its involvement in RNA editing. |journal=J. Biol. Chem. |volume=272 |issue= 3 |pages= 1452-5 |year= 1997 |pmid= 8999813 |doi=  }}
+*{{cite journal  |vauthors=Lau PP, Zhu HJ, Nakamuta M, Chan L |title=Cloning of an Apobec-1-binding protein that also interacts with apolipoprotein B mRNA and evidence for its involvement in RNA editing. |journal=J. Biol. Chem. |volume=272 |issue= 3 |pages= 1452–5 |year= 1997 |pmid= 8999813 |doi=10.1074/jbc.272.3.1452  }}
-*{{cite journal  | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, ''et al.'' |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149-56 |year= 1997 |pmid= 9373149 |doi=  }}
+*{{cite journal   |vauthors=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, etal |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=10.1016/S0378-1119(97)00411-3  }}
-*{{cite journal  | author=Hay DC, Kemp GD, Dargemont C, Hay RT |title=Interaction between hnRNPA1 and IkappaBalpha is required for maximal activation of NF-kappaB-dependent transcription. |journal=Mol. Cell. Biol. |volume=21 |issue= 10 |pages= 3482-90 |year= 2001 |pmid= 11313474 |doi= 10.1128/MCB.21.10.3482-3490.2001 }}
+*{{cite journal  |vauthors=Hay DC, Kemp GD, Dargemont C, Hay RT |title=Interaction between hnRNPA1 and IkappaBalpha is required for maximal activation of NF-kappaB-dependent transcription. |journal=Mol. Cell. Biol. |volume=21 |issue= 10 |pages= 3482–90 |year= 2001 |pmid= 11313474 |doi= 10.1128/MCB.21.10.3482-3490.2001  | pmc=100270 }}
-*{{cite journal  | author=Lau PP, Chang BH, Chan L |title=Two-hybrid cloning identifies an RNA-binding protein, GRY-RBP, as a component of apobec-1 editosome. |journal=Biochem. Biophys. Res. Commun. |volume=282 |issue= 4 |pages= 977-83 |year= 2001 |pmid= 11352648 |doi= 10.1006/bbrc.2001.4679 }}
+*{{cite journal  |vauthors=Lau PP, Chang BH, Chan L |title=Two-hybrid cloning identifies an RNA-binding protein, GRY-RBP, as a component of apobec-1 editosome. |journal=Biochem. Biophys. Res. Commun. |volume=282 |issue= 4 |pages= 977–83 |year= 2001 |pmid= 11352648 |doi= 10.1006/bbrc.2001.4679 }}
-*{{cite journal  | author=Gallouzi IE, Brennan CM, Steitz JA |title=Protein ligands mediate the CRM1-dependent export of HuR in response to heat shock. |journal=RNA |volume=7 |issue= 9 |pages= 1348-61 |year= 2001 |pmid= 11565755 |doi=  }}
+*{{cite journal  |vauthors=Gallouzi IE, Brennan CM, Steitz JA |title=Protein ligands mediate the CRM1-dependent export of HuR in response to heat shock. |journal=RNA |volume=7 |issue= 9 |pages= 1348–61 |year= 2001 |pmid= 11565755 |doi=10.1017/S1355838201016089  | pmc=1370177  }}{{Retracted paper}}
-*{{cite journal  | author=Andersen JS, Lyon CE, Fox AH, ''et al.'' |title=Directed proteomic analysis of the human nucleolus. |journal=Curr. Biol. |volume=12 |issue= 1 |pages= 1-11 |year= 2002 |pmid= 11790298 |doi=  }}
+*{{cite journal   |vauthors=Andersen JS, Lyon CE, Fox AH, etal |title=Directed proteomic analysis of the human nucleolus. |journal=Curr. Biol. |volume=12 |issue= 1 |pages= 1–11 |year= 2002 |pmid= 11790298 |doi=10.1016/S0960-9822(01)00650-9  }}
-*{{cite journal  | author=Percipalle P, Jonsson A, Nashchekin D, ''et al.'' |title=Nuclear actin is associated with a specific subset of hnRNP A/B-type proteins. |journal=Nucleic Acids Res. |volume=30 |issue= 8 |pages= 1725-34 |year= 2002 |pmid= 11937625 |doi=  }}
+*{{cite journal   |vauthors=Percipalle P, Jonsson A, Nashchekin D, etal |title=Nuclear actin is associated with a specific subset of hnRNP A/B-type proteins. |journal=Nucleic Acids Res. |volume=30 |issue= 8 |pages= 1725–34 |year= 2002 |pmid= 11937625 |doi=10.1093/nar/30.8.1725  | pmc=113215  }}
-*{{cite journal  | author=Angenstein F, Evans AM, Settlage RE, ''et al.'' |title=A receptor for activated C kinase is part of messenger ribonucleoprotein complexes associated with polyA-mRNAs in neurons. |journal=J. Neurosci. |volume=22 |issue= 20 |pages= 8827-37 |year= 2002 |pmid= 12388589 |doi=  }}
+*{{cite journal   |vauthors=Angenstein F, Evans AM, Settlage RE, etal |title=A receptor for activated C kinase is part of messenger ribonucleoprotein complexes associated with polyA-mRNAs in neurons. |journal=J. Neurosci. |volume=22 |issue= 20 |pages= 8827–37 |year= 2002 |pmid= 12388589 |doi=  }}
-*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
+*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 }}
-*{{cite journal  | author=Fomenkov A, Huang YP, Topaloglu O, ''et al.'' |title=P63 alpha mutations lead to aberrant splicing of keratinocyte growth factor receptor in the Hay-Wells syndrome. |journal=J. Biol. Chem. |volume=278 |issue= 26 |pages= 23906-14 |year= 2003 |pmid= 12692135 |doi= 10.1074/jbc.M300746200 }}
+*{{cite journal   |vauthors=Fomenkov A, Huang YP, Topaloglu O, etal |title=P63 alpha mutations lead to aberrant splicing of keratinocyte growth factor receptor in the Hay-Wells syndrome. |journal=J. Biol. Chem. |volume=278 |issue= 26 |pages= 23906–14 |year= 2003 |pmid= 12692135 |doi= 10.1074/jbc.M300746200 }}
-*{{cite journal  | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
+*{{cite journal   |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
-*{{cite journal  | author=Zhang S, Schlott B, Görlach M, Grosse F |title=DNA-dependent protein kinase (DNA-PK) phosphorylates nuclear DNA helicase II/RNA helicase A and hnRNP proteins in an RNA-dependent manner. |journal=Nucleic Acids Res. |volume=32 |issue= 1 |pages= 1-10 |year= 2004 |pmid= 14704337 |doi= 10.1093/nar/gkg933 }}
+*{{cite journal  |vauthors=Zhang S, Schlott B, Görlach M, Grosse F |title=DNA-dependent protein kinase (DNA-PK) phosphorylates nuclear DNA helicase II/RNA helicase A and hnRNP proteins in an RNA-dependent manner. |journal=Nucleic Acids Res. |volume=32 |issue= 1 |pages= 1–10 |year= 2004 |pmid= 14704337 |doi= 10.1093/nar/gkg933  | pmc=373260 }}
-*{{cite journal  | author=Gao C, Guo H, Wei J, ''et al.'' |title=S-nitrosylation of heterogeneous nuclear ribonucleoprotein A/B regulates osteopontin transcription in endotoxin-stimulated murine macrophages. |journal=J. Biol. Chem. |volume=279 |issue= 12 |pages= 11236-43 |year= 2004 |pmid= 14722087 |doi= 10.1074/jbc.M313385200 }}
+*{{cite journal   |vauthors=Gao C, Guo H, Wei J, etal |title=S-nitrosylation of heterogeneous nuclear ribonucleoprotein A/B regulates osteopontin transcription in endotoxin-stimulated murine macrophages. |journal=J. Biol. Chem. |volume=279 |issue= 12 |pages= 11236–43 |year= 2004 |pmid= 14722087 |doi= 10.1074/jbc.M313385200 }}
-*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
+*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504  | pmc=528928 }}
-*{{cite journal  | author=Ong SE, Mittler G, Mann M |title=Identifying and quantifying in vivo methylation sites by heavy methyl SILAC. |journal=Nat. Methods |volume=1 |issue= 2 |pages= 119-26 |year= 2005 |pmid= 15782174 |doi= 10.1038/nmeth715 }}
+*{{cite journal  |vauthors=Ong SE, Mittler G, Mann M |title=Identifying and quantifying in vivo methylation sites by heavy methyl SILAC. |journal=Nat. Methods |volume=1 |issue= 2 |pages= 119–26 |year= 2005 |pmid= 15782174 |doi= 10.1038/nmeth715 }}
-*{{cite journal  | author=Beausoleil SA, Villén J, Gerber SA, ''et al.'' |title=A probability-based approach for high-throughput protein phosphorylation analysis and site localization. |journal=Nat. Biotechnol. |volume=24 |issue= 10 |pages= 1285-92 |year= 2006 |pmid= 16964243 |doi= 10.1038/nbt1240 }}
+*{{cite journal   |vauthors=Beausoleil SA, Villén J, Gerber SA, etal |title=A probability-based approach for high-throughput protein phosphorylation analysis and site localization. |journal=Nat. Biotechnol. |volume=24 |issue= 10 |pages= 1285–92 |year= 2006 |pmid= 16964243 |doi= 10.1038/nbt1240 }}
-*{{cite journal  | author=Ewing RM, Chu P, Elisma F, ''et al.'' |title=Large-scale mapping of human protein-protein interactions by mass spectrometry. |journal=Mol. Syst. Biol. |volume=3 |issue=  |pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134 }}
+*{{cite journal   |vauthors=Ewing RM, Chu P, Elisma F, etal |title=Large-scale mapping of human protein-protein interactions by mass spectrometry. |journal=Mol. Syst. Biol. |volume=3 |issue=  1|pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134  | pmc=1847948 }}
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HNRPAB: Difference between revisions

Revision as of 13:58, 31 August 2017

Contents

Function

Interactions

References

Further reading

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