TRAK1: Difference between revisions

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{{Underlinked|date=March 2014}}
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{{Infobox_gene}}
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'''Trafficking kinesin-binding protein 1''' is a [[protein]] that in humans is encoded by the ''TRAK1'' [[gene]].<ref name="pmid10470851">{{cite journal |vauthors=Kikuno R, Nagase T, Ishikawa K, Hirosawa M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O | title = Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro | journal = DNA Res | volume = 6 | issue = 3 | pages = 197–205 |date=Oct 1999 | pmid = 10470851 | pmc =  | doi =10.1093/dnares/6.3.197 }}</ref><ref name="pmid12435728">{{cite journal |vauthors=Iyer SP, Akimoto Y, Hart GW | title = Identification and cloning of a novel family of coiled-coil domain proteins that interact with O-GlcNAc transferase | journal = J Biol Chem | volume = 278 | issue = 7 | pages = 5399–409 |date=Feb 2003 | pmid = 12435728 | pmc =  | doi = 10.1074/jbc.M209384200 }}</ref><ref name="pmid16380713">{{cite journal |vauthors=Gilbert SL, Zhang L, Forster ML, Anderson JR, Iwase T, Soliven B, Donahue LR, Sweet HO, Bronson RT, Davisson MT, Wollmann RL, Lahn BT | title = Trak1 mutation disrupts GABA(A) receptor homeostasis in hypertonic mice | journal = Nat Genet | volume = 38 | issue = 2 | pages = 245–50 |date=Jan 2006 | pmid = 16380713 | pmc =  | doi = 10.1038/ng1715 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: TRAK1 trafficking protein, kinesin binding 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=22906| accessdate = }}</ref>
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{{GNF_Protein_box
| image =
| image_source =
| PDB =  
| Name = Trafficking protein, kinesin binding 1
| HGNCid = 29947
| Symbol = TRAK1
| AltSymbols =; OIP106
| OMIM = 608112
| ECnumber =
| Homologene = 86983
  | MGIid = 1914345
| GeneAtlas_image1 = PBB_GE_TRAK1_201283_s_at_tn.png
| GeneAtlas_image2 = PBB_GE_TRAK1_202079_s_at_tn.png
| GeneAtlas_image3 = PBB_GE_TRAK1_202080_s_at_tn.png
  | Function = {{GNF_GO|id=GO:0005515 |text = protein binding}} {{GNF_GO|id=GO:0019895 |text = kinesin-associated mitochondrial adaptor activity}} {{GNF_GO|id=GO:0050811 |text = GABA receptor binding}}
| Component = {{GNF_GO|id=GO:0005634 |text = nucleus}} {{GNF_GO|id=GO:0005739 |text = mitochondrion}}
  | Process = {{GNF_GO|id=GO:0006357 |text = regulation of transcription from RNA polymerase II promoter}} {{GNF_GO|id=GO:0006493 |text = protein amino acid O-linked glycosylation}} {{GNF_GO|id=GO:0006605 |text = protein targeting}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 22906
    | Hs_Ensembl = ENSG00000182606
    | Hs_RefseqProtein = NP_001036111
    | Hs_RefseqmRNA = NM_001042646
    | Hs_GenLoc_db =
    | Hs_GenLoc_chr = 3
    | Hs_GenLoc_start = 42107750
    | Hs_GenLoc_end = 42242264
    | Hs_Uniprot = Q9UPV9
    | Mm_EntrezGene = 67095
    | Mm_Ensembl = ENSMUSG00000032536
    | Mm_RefseqmRNA = XM_001001035
    | Mm_RefseqProtein = XP_001001035
    | Mm_GenLoc_db =   
    | Mm_GenLoc_chr = 9
    | Mm_GenLoc_start = 121146230
    | Mm_GenLoc_end = 121323614
    | Mm_Uniprot = 
  }}
}}
'''Trafficking protein, kinesin binding 1''', also known as '''TRAK1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: TRAK1 trafficking protein, kinesin binding 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=22906| accessdate = }}</ref>
 
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==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal  | author=Kikuno R, Nagase T, Ishikawa K, ''et al.'' |title=Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. |journal=DNA Res. |volume=6 |issue= 3 |pages= 197-205 |year= 1999 |pmid= 10470851 |doi=  }}
*{{cite journal  |vauthors=Hartley JL, Temple GF, Brasch MA |title=DNA Cloning Using In Vitro Site-Specific Recombination |journal=Genome Res. |volume=10 |issue= 11 |pages= 1788–95 |year= 2001 |pmid= 11076863 |doi=10.1101/gr.143000  | pmc=310948 }}
*{{cite journal  | author=Hartley JL, Temple GF, Brasch MA |title=DNA cloning using in vitro site-specific recombination. |journal=Genome Res. |volume=10 |issue= 11 |pages= 1788-95 |year= 2001 |pmid= 11076863 |doi=  }}
*{{cite journal  | author=Wiemann S |title=Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs |journal=Genome Res. |volume=11 |issue= 3 |pages= 422–35 |year= 2001 |pmid= 11230166 |doi= 10.1101/gr.GR1547R  | pmc=311072 |name-list-format=vanc| author2=Weil B  | author3=Wellenreuther R  | display-authors=3  | last4=Gassenhuber  | first4=J | last5=Glassl  | first5=S  | last6=Ansorge  | first6=W  | last7=Böcher  | first7=M  | last8=Blöcker  | first8=H  | last9=Bauersachs  | first9=S }}
*{{cite journal  | author=Wiemann S, Weil B, Wellenreuther R, ''et al.'' |title=Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. |journal=Genome Res. |volume=11 |issue= 3 |pages= 422-35 |year= 2001 |pmid= 11230166 |doi= 10.1101/gr.154701 }}
*{{cite journal  | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241  |name-list-format=vanc| author2=Feingold EA  | author3=Grouse LH  | display-authors=3  | last4=Derge  | first4=JG  | last5=Klausner  | first5=RD  | last6=Collins  | first6=FS  | last7=Wagner  | first7=L  | last8=Shenmen  | first8=CM  | last9=Schuler  | first9=GD }}
*{{cite journal | author=Iyer SP, Akimoto Y, Hart GW |title=Identification and cloning of a novel family of coiled-coil domain proteins that interact with O-GlcNAc transferase. |journal=J. Biol. Chem. |volume=278 |issue= 7 |pages= 5399-409 |year= 2003 |pmid= 12435728 |doi= 10.1074/jbc.M209384200 }}
*{{cite journal  |vauthors=Iyer SP, Hart GW |title=Roles of the tetratricopeptide repeat domain in O-GlcNAc transferase targeting and protein substrate specificity |journal=J. Biol. Chem. |volume=278 |issue= 27 |pages= 24608–16 |year= 2003 |pmid= 12724313 |doi= 10.1074/jbc.M300036200 }}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | author=Ota T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |name-list-format=vanc| author2=Suzuki Y  | author3=Nishikawa T  | display-authors=3  | last4=Otsuki  | first4=Tetsuji  | last5=Sugiyama  | first5=Tomoyasu  | last6=Irie  | first6=Ryotaro  | last7=Wakamatsu  | first7=Ai  | last8=Hayashi  | first8=Koji  | last9=Sato  | first9=Hiroyuki }}
*{{cite journal  | author=Iyer SP, Hart GW |title=Roles of the tetratricopeptide repeat domain in O-GlcNAc transferase targeting and protein substrate specificity. |journal=J. Biol. Chem. |volume=278 |issue= 27 |pages= 24608-16 |year= 2003 |pmid= 12724313 |doi= 10.1074/jbc.M300036200 }}
*{{cite journal  | author=Colland F |title=Functional Proteomics Mapping of a Human Signaling Pathway |journal=Genome Res. |volume=14 |issue= 7 |pages= 1324–32 |year= 2004 |pmid= 15231748 |doi= 10.1101/gr.2334104 | pmc=442148  |name-list-format=vanc| author2=Jacq X  | author3=Trouplin V  | display-authors=3  | last4=Mougin  | first4=C  | last5=Groizeleau  | first5=C  | last6=Hamburger  | first6=A  | last7=Meil  | first7=A  | last8=Wojcik  | first8=J  | last9=Legrain  | first9=P }}
*{{cite journal  | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal  | author=Gerhard DS |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928  |name-list-format=vanc| author2=Wagner L  | author3=Feingold EA  | display-authors=3  | last4=Shenmen  | first4=CM  | last5=Grouse  | first5=LH  | last6=Schuler  | first6=G  | last7=Klein  | first7=SL  | last8=Old  | first8=S  | last9=Rasooly  | first9=R }}
*{{cite journal  | author=Colland F, Jacq X, Trouplin V, ''et al.'' |title=Functional proteomics mapping of a human signaling pathway. |journal=Genome Res. |volume=14 |issue= 7 |pages= 1324-32 |year= 2004 |pmid= 15231748 |doi= 10.1101/gr.2334104 }}
*{{cite journal  | author=Wiemann S |title=From ORFeome to Biology: A Functional Genomics Pipeline |journal=Genome Res. |volume=14 |issue= 10B |pages= 2136–44 |year= 2004 |pmid= 15489336 |doi= 10.1101/gr.2576704 | pmc=528930  |name-list-format=vanc| author2=Arlt D  | author3=Huber W  | display-authors=3  | last4=Wellenreuther  | first4=R  | last5=Schleeger  | first5=S  | last6=Mehrle  | first6=A  | last7=Bechtel  | first7=S  | last8=Sauermann  | first8=M  | last9=Korf  | first9=U }}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal  |vauthors=Brickley K, Smith MJ, Beck M, Stephenson FA |title=GRIF-1 and OIP106, members of a novel gene family of coiled-coil domain proteins: association in vivo and in vitro with kinesin |journal=J. Biol. Chem. |volume=280 |issue= 15 |pages= 14723–32 |year= 2005 |pmid= 15644324 |doi= 10.1074/jbc.M409095200 }}
*{{cite journal  | author=Wiemann S, Arlt D, Huber W, ''et al.'' |title=From ORFeome to biology: a functional genomics pipeline. |journal=Genome Res. |volume=14 |issue= 10B |pages= 2136-44 |year= 2004 |pmid= 15489336 |doi= 10.1101/gr.2576704 }}
*{{cite journal  | author=Ozyildirim AM |title=The lacrimal gland transcriptome is an unusually rich source of rare and poorly characterized gene transcripts |journal=Invest. Ophthalmol. Vis. Sci. |volume=46 |issue= 5 |pages= 1572–80 |year= 2005 |pmid= 15851553 |doi= 10.1167/iovs.04-1380  |name-list-format=vanc| author2=Wistow GJ  | author3=Gao J  | display-authors=3  | last4=Wang  | first4=J  | last5=Dickinson  | first5=DP  | last6=Frierson Jr  | first6=HF  | last7=Laurie  | first7=GW }}
*{{cite journal  | author=Brickley K, Smith MJ, Beck M, Stephenson FA |title=GRIF-1 and OIP106, members of a novel gene family of coiled-coil domain proteins: association in vivo and in vitro with kinesin. |journal=J. Biol. Chem. |volume=280 |issue= 15 |pages= 14723-32 |year= 2005 |pmid= 15644324 |doi= 10.1074/jbc.M409095200 }}
*{{cite journal  | author=Mehrle A |title=The LIFEdb database in 2006 |journal=Nucleic Acids Res. |volume=34 |issue= Database issue |pages= D415–8 |year= 2006 |pmid= 16381901 |doi= 10.1093/nar/gkj139 | pmc=1347501  |name-list-format=vanc| author2=Rosenfelder H  | author3=Schupp I  | display-authors=3  | last4=Del Val  | first4=C  | last5=Arlt  | first5=D  | last6=Hahne  | first6=F  | last7=Bechtel  | first7=S  | last8=Simpson  | first8=J  | last9=Hofmann  | first9=O }}
*{{cite journal  | author=Ozyildirim AM, Wistow GJ, Gao J, ''et al.'' |title=The lacrimal gland transcriptome is an unusually rich source of rare and poorly characterized gene transcripts. |journal=Invest. Ophthalmol. Vis. Sci. |volume=46 |issue= 5 |pages= 1572-80 |year= 2005 |pmid= 15851553 |doi= 10.1167/iovs.04-1380 }}
*{{cite journal  |vauthors=Fransson S, Ruusala A, Aspenström P |title=The atypical Rho GTPases Miro-1 and Miro-2 have essential roles in mitochondrial trafficking |journal=Biochem. Biophys. Res. Commun. |volume=344 |issue= 2 |pages= 500–10 |year= 2006 |pmid= 16630562 |doi= 10.1016/j.bbrc.2006.03.163 }}
*{{cite journal | author=Gilbert SL, Zhang L, Forster ML, ''et al.'' |title=Trak1 mutation disrupts GABA(A) receptor homeostasis in hypertonic mice. |journal=Nat. Genet. |volume=38 |issue= 2 |pages= 245-50 |year= 2006 |pmid= 16380713 |doi= 10.1038/ng1715 }}
*{{cite journal  | author=Mehrle A, Rosenfelder H, Schupp I, ''et al.'' |title=The LIFEdb database in 2006. |journal=Nucleic Acids Res. |volume=34 |issue= Database issue |pages= D415-8 |year= 2006 |pmid= 16381901 |doi= 10.1093/nar/gkj139 }}
*{{cite journal  | author=Fransson S, Ruusala A, Aspenström P |title=The atypical Rho GTPases Miro-1 and Miro-2 have essential roles in mitochondrial trafficking. |journal=Biochem. Biophys. Res. Commun. |volume=344 |issue= 2 |pages= 500-10 |year= 2006 |pmid= 16630562 |doi= 10.1016/j.bbrc.2006.03.163 }}
}}
}}
{{refend}}
{{refend}}


{{protein-stub}}
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Revision as of 12:14, 15 September 2017

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Trafficking kinesin-binding protein 1 is a protein that in humans is encoded by the TRAK1 gene.[1][2][3][4]


References

  1. ↑ Kikuno R, Nagase T, Ishikawa K, Hirosawa M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Oct 1999). "Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 6 (3): 197–205. doi:10.1093/dnares/6.3.197. PMID 10470851.
  2. ↑ Iyer SP, Akimoto Y, Hart GW (Feb 2003). "Identification and cloning of a novel family of coiled-coil domain proteins that interact with O-GlcNAc transferase". J Biol Chem. 278 (7): 5399–409. doi:10.1074/jbc.M209384200. PMID 12435728.
  3. ↑ Gilbert SL, Zhang L, Forster ML, Anderson JR, Iwase T, Soliven B, Donahue LR, Sweet HO, Bronson RT, Davisson MT, Wollmann RL, Lahn BT (Jan 2006). "Trak1 mutation disrupts GABA(A) receptor homeostasis in hypertonic mice". Nat Genet. 38 (2): 245–50. doi:10.1038/ng1715. PMID 16380713.
  4. ↑ "Entrez Gene: TRAK1 trafficking protein, kinesin binding 1".

Further reading



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