Mesenteric ischemia medical therapy

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Feham Tariq, MD [2]

Overview

Acute mesenteric artery ischemia is an emergency.Thrombolytics may be required to dissolve the clot, and vasodilators may be needed to widen the mesenteric arteries (vasodilators). Further treatment with surgery may still be required.

Medical Therapy

• Pharmacologic medical therapy is recommended among patients with [disease subclass 1], [disease subclass 2], and [disease subclass 3].
• Pharmacologic medical therapies for [disease name] include (either) [therapy 1], [therapy 2], and/or [therapy 3].
• Empiric therapy for [disease name] depends on [disease factor 1] and [disease factor 2].
• Patients with [disease subclass 1] are treated with [therapy 1], whereas patients with [disease subclass 2] are treated with [therapy 2].

Multimodal management of mesenteric ischemia
Early management				Late management
Vascular occlusion	Splanchnic hypoperfusion	Intestinal hypoxia	Intestinal barrier injury Translocation Local inflammatory pathway	Systemic inflammatory pathways	Necrosis Organ failure
Heparin Aspirin Revascularization	Oxygen Blood volume resuscitation Transfusion		Oral antibiotics	Intravenous antibiotics	Intestinal resection