Short bowel syndrome pathophysiology: Difference between revisions
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==Gross Pathology== | ==Gross Pathology== | ||
*On gross pathology, | *On gross pathology, the resected bowel may show the underlying causes including Crohn's disease, malignancies or ischemia. | ||
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|[[image:ResectedIleum.jpg|thumb| | |[[image:ResectedIleum.jpg|thumb|410px|center|Terminal ileum resected for Crohn's disease. | ||
By PPSE15 - Own work, CC BY-SA 4.0<ref name="urlFile:ResectedIleum.jpg - Wikimedia Commons">{{cite web |url=https://commons.wikimedia.org/w/index.php?curid=39360128 |title=File:ResectedIleum.jpg - Wikimedia Commons |format= |work= |accessdate=}}</ref>]] | By PPSE15 - Own work, CC BY-SA 4.0<ref name="urlFile:ResectedIleum.jpg - Wikimedia Commons">{{cite web |url=https://commons.wikimedia.org/w/index.php?curid=39360128 |title=File:ResectedIleum.jpg - Wikimedia Commons |format= |work= |accessdate=}}</ref>]] | ||
|} | |} | ||
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|[[image:Crohn Jejunum.png|thumb|500px|center|Partial jejunum affected by morbus Crohn. | |||
Source: Wikimedia.org By Jaroslav Cehovsky - Camera, Public Domain<ref name="urlFile:Crohn Jejunum.PNG - Wikimedia Commons">{{cite web |url=https://commons.wikimedia.org/w/index.php?curid=1458390 |title=File:Crohn Jejunum.PNG - Wikimedia Commons |format= |work= |accessdate=}}</ref>]] | |||
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==Microscopic Pathology== | ==Microscopic Pathology== | ||
*On microscopic histopathological analysis, [feature1], [feature2], and [feature3] are characteristic findings of [disease name]. | *On microscopic histopathological analysis, [feature1], [feature2], and [feature3] are characteristic findings of [disease name]. | ||
Revision as of 14:33, 5 December 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sadaf Sharfaei M.D.[2]
Overview
The exact pathogenesis of [disease name] is not fully understood.
OR
It is thought that [disease name] is the result of / is mediated by / is produced by / is caused by either [hypothesis 1], [hypothesis 2], or [hypothesis 3].
OR
[Pathogen name] is usually transmitted via the [transmission route] route to the human host.
OR
Following transmission/ingestion, the [pathogen] uses the [entry site] to invade the [cell name] cell.
OR
[Disease or malignancy name] arises from [cell name]s, which are [cell type] cells that are normally involved in [function of cells].
OR
The progression to [disease name] usually involves the [molecular pathway].
OR
The pathophysiology of [disease/malignancy] depends on the histological subtype.
Pathophysiology
Physiology
The small intestine has an average length of 3-6 meters and is responsible for absorbing nutrients. Absorption mostly occurs in duodenum and jejunum rather than ileum. There is an anatomic gradient for absorption throughout the gastrointestinal tract.[1]
Pathogenesis
- The exact pathogenesis of [disease name] is not fully understood.
OR
- It is thought that [disease name] is the result of / is mediated by / is produced by / is caused by either [hypothesis 1], [hypothesis 2], or [hypothesis 3].
- [Pathogen name] is usually transmitted via the [transmission route] route to the human host.
- Following transmission/ingestion, the [pathogen] uses the [entry site] to invade the [cell name] cell.
- [Disease or malignancy name] arises from [cell name]s, which are [cell type] cells that are normally involved in [function of cells].
- The progression to [disease name] usually involves the [molecular pathway].
- The pathophysiology of [disease/malignancy] depends on the histological subtype.
Associated Conditions
Gross Pathology
- On gross pathology, the resected bowel may show the underlying causes including Crohn's disease, malignancies or ischemia.
 |
 |
Microscopic Pathology
- On microscopic histopathological analysis, [feature1], [feature2], and [feature3] are characteristic findings of [disease name].
References
- ↑ Tappenden KA (2014). "Pathophysiology of short bowel syndrome: considerations of resected and residual anatomy". JPEN J Parenter Enteral Nutr. 38 (1 Suppl): 14S–22S. doi:10.1177/0148607113520005. PMID 24500909.
- ↑ "File:ResectedIleum.jpg - Wikimedia Commons". External link in
|title=(help) - ↑ "File:Crohn Jejunum.PNG - Wikimedia Commons".