Chronic pancreatitis causes: Difference between revisions

Jump to navigation Jump to search
Line 7: Line 7:
==Causes==
==Causes==
The causes of pancreatitis are many but at least 70% of adult cases are associated with chronic alcohol use, and most patients have consumed more than 80 g/day of alcohol over six to twelve years.<ref>{{cite journal |journal=Am Fam Physician |date=2007 |volume=76 |issue=11 |pages=1679–88 |title= Chronic pancreatitis |author= Nair RJ, Lawler L, Miller MR |pmid=18092710 |url=http://www.aafp.org/afp/20071201/1679.html}}</ref><ref>Mitchell RMS et al. Pancreatitis. Lancet 2003; 361: 1447–55</ref>
The causes of pancreatitis are many but at least 70% of adult cases are associated with chronic alcohol use, and most patients have consumed more than 80 g/day of alcohol over six to twelve years.<ref>{{cite journal |journal=Am Fam Physician |date=2007 |volume=76 |issue=11 |pages=1679–88 |title= Chronic pancreatitis |author= Nair RJ, Lawler L, Miller MR |pmid=18092710 |url=http://www.aafp.org/afp/20071201/1679.html}}</ref><ref>Mitchell RMS et al. Pancreatitis. Lancet 2003; 361: 1447–55</ref>
* Major Associations with Chronic Pancreatitis <ref>Mitchell RMS et al. Pancreatitis. Lancet 2003; 361: 1447–55</ref><ref>Frulloni et al. Chronic pancreatitis: Report from a multicenter Italian survey (PanCroInfAISP) on 893 patients. Dig Liver Dis. 2009 Apr;41(4):311-7</ref><ref>Adsay NV et al. Paraduodenal pancreatitis: a clinico-pathologically distinct entity unifying "cystic dystrophy of heterotopic pancreas", "para-duodenal wall cyst", and "groove pancreatitis". Semin Diagn Pathol. 2004 Nov;21(4):247-54. </ref>
* Major associations with chronic pancreatitis <ref>Mitchell RMS et al. Pancreatitis. Lancet 2003; 361: 1447–55</ref><ref>Frulloni et al. Chronic pancreatitis: Report from a multicenter Italian survey (PanCroInfAISP) on 893 patients. Dig Liver Dis. 2009 Apr;41(4):311-7</ref><ref>Adsay NV et al. Paraduodenal pancreatitis: a clinico-pathologically distinct entity unifying "cystic dystrophy of heterotopic pancreas", "para-duodenal wall cyst", and "groove pancreatitis". Semin Diagn Pathol. 2004 Nov;21(4):247-54. </ref>
** Alcohol
** Alcohol
*** ≥80 g of ethanol consumption a day for at least 5 years.
*** ≥80 g of ethanol consumption a day for at least 5 years
*** Most common cause in men
*** Least common cause in women
** Autoimmunity  
** Autoimmunity  
*** Autoimmune pancreatitis
*** Autoimmune pancreatitis

Revision as of 19:42, 1 November 2017

Chronic pancreatitis Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Chronic pancreatitis from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

Diagnostic Criteria

History and Symptoms

Physical Examination

Laboratory Findings

Abdominal X Ray

CT

MRI

Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

American Pancreatic Association Practice Guidelines

APA Clinical Practice Guidelines for Chronic pancreatiits

Chronic pancreatitis causes On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Chronic pancreatitis causes

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Chronic pancreatitis causes

CDC on Chronic pancreatitis causes

Chronic pancreatitis causes in the news

Blogs on Chronic pancreatitis causes

Directions to Hospitals Treating Chronic pancreatitis

Risk calculators and risk factors for Chronic pancreatitis causes

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Causes

The causes of pancreatitis are many but at least 70% of adult cases are associated with chronic alcohol use, and most patients have consumed more than 80 g/day of alcohol over six to twelve years.[1][2]

  • Major associations with chronic pancreatitis [3][4][5]
    • Alcohol
      • ≥80 g of ethanol consumption a day for at least 5 years
      • Most common cause in men
      • Least common cause in women
    • Autoimmunity
      • Autoimmune pancreatitis
      • Associated with other systemic disorders (Sjogren syndrome, inflammatory bowel disease, or primary biliary cholangitis)
    • Obstruction
      • Fibrotic stenosis of either the papilla of Vater or the main pancreatic duct
      • Trauma
      • Pseudocysts
      • Stones
      • Tumors
      • Pancreas divisum
    • Anatomic variations
      • Pancreas divisum
      • Paraduodenal pancreatitis (Cystic dystrophy of the duodenal wall/groove pancreatitis)
    • Metabolic or systemic diseases
      • Hypercalcemia
      • Hypertryglyceridemia
      • Hyperparathyroidism
      • Systemic lupus erythematosus
    • Genetic
      • CFTR
      • CTRC
      • SPINK1
      • PRSS1 gene mutations
      • Hereditary pancreatitis
    • Idiopathic

References

  1. Nair RJ, Lawler L, Miller MR (2007). "Chronic pancreatitis". Am Fam Physician. 76 (11): 1679–88. PMID 18092710.
  2. Mitchell RMS et al. Pancreatitis. Lancet 2003; 361: 1447–55
  3. Mitchell RMS et al. Pancreatitis. Lancet 2003; 361: 1447–55
  4. Frulloni et al. Chronic pancreatitis: Report from a multicenter Italian survey (PanCroInfAISP) on 893 patients. Dig Liver Dis. 2009 Apr;41(4):311-7
  5. Adsay NV et al. Paraduodenal pancreatitis: a clinico-pathologically distinct entity unifying "cystic dystrophy of heterotopic pancreas", "para-duodenal wall cyst", and "groove pancreatitis". Semin Diagn Pathol. 2004 Nov;21(4):247-54.


Template:WikiDoc Sources