African trypanosomiasis classification: Difference between revisions

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{{CMG}}; {{AE}} {{ADG}}
{{CMG}}; {{AE}} {{ADG}}
==Overview==
==Overview==
African trypanosomiasis can be classified based upon the [[pathogen]] and geographic location into two types East African trypanosomiasis and West African trypanosomiasis.<ref name="pmid16308383">{{cite journal |vauthors=Picozzi K, Fèvre EM, Odiit M, Carrington M, Eisler MC, Maudlin I, Welburn SC |title=Sleeping sickness in Uganda: a thin line between two fatal diseases |journal=BMJ |volume=331 |issue=7527 |pages=1238–41 |year=2005 |pmid=16308383 |pmc=1289320 |doi=10.1136/bmj.331.7527.1238 |url=}}</ref>
[[African trypanosomiasis]] can be classified based upon the [[pathogen]] and geographic location into two types [[Trypanosomiasis, east-African|East African trypanosomiasis]] and [[Trypanosomiasis, west African|West African trypanosomiasis]].<ref name="pmid16308383">{{cite journal |vauthors=Picozzi K, Fèvre EM, Odiit M, Carrington M, Eisler MC, Maudlin I, Welburn SC |title=Sleeping sickness in Uganda: a thin line between two fatal diseases |journal=BMJ |volume=331 |issue=7527 |pages=1238–41 |year=2005 |pmid=16308383 |pmc=1289320 |doi=10.1136/bmj.331.7527.1238 |url=}}</ref>


==Classification==
==Classification==
African trypanosomiasis can be classified based upon the [[pathogen]] and geographic location into two types East African trypanosomiasis and West African trypanosomiasis.
[[African trypanosomiasis]] can be classified based upon the [[pathogen]] and geographic location into two types [[Trypanosomiasis, east-African|East African trypanosomiasis]] and [[Trypanosomiasis, west African|West African trypanosomiasis]].
{| class="wikitable"
{| class="wikitable"
! rowspan="2" |Disease
! rowspan="2" |Disease
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* [[Itching]] of the skin, [[swollen lymph nodes]], and [[weight loss]]  
* [[Itching]] of the skin, [[swollen lymph nodes]], and [[weight loss]]  
|
|
* Personality changes, [[daytime sleepiness]] with nighttime sleep disturbance, and progressive confusion
* Personality changes, [[daytime sleepiness]] with nighttime sleep disturbance, and progressive [[confusion]]
* Other [[Neurological disorders|neurologic]] signs, such as partial [[paralysis]] or problems with balance or walking may occur, as well as hormonal imbalances
* Other [[Neurological disorders|neurologic]] signs, such as partial [[paralysis]] or problems with balance or walking may occur, as well as hormonal imbalances
* The course of untreated [[infection]] rarely lasts longer than 6-7 years and more often kills in about 3 years.
* The course of untreated [[infection]] rarely lasts longer than 6-7 years and more often kills in about 3 years.

Revision as of 14:23, 26 July 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aditya Ganti M.B.B.S. [2]

Overview

African trypanosomiasis can be classified based upon the pathogen and geographic location into two types East African trypanosomiasis and West African trypanosomiasis.[1]

Classification

African trypanosomiasis can be classified based upon the pathogen and geographic location into two types East African trypanosomiasis and West African trypanosomiasis.

Disease Pathogen Geographic

distrubution

Progression Symptoms
First stage Second stage
East African sleeping sickness Trypanosoma brucei rhodesiense East and Southeast Africa Rapid

(1-2 weeks)

West African sleeping sickness Trypanosoma brucei gambiense West and Central Africa Slow

(1-2 years)

  • Personality changes, daytime sleepiness with nighttime sleep disturbance, and progressive confusion
  • Other neurologic signs, such as partial paralysis or problems with balance or walking may occur, as well as hormonal imbalances
  • The course of untreated infection rarely lasts longer than 6-7 years and more often kills in about 3 years.

References

  1. Picozzi K, Fèvre EM, Odiit M, Carrington M, Eisler MC, Maudlin I, Welburn SC (2005). "Sleeping sickness in Uganda: a thin line between two fatal diseases". BMJ. 331 (7527): 1238–41. doi:10.1136/bmj.331.7527.1238. PMC 1289320. PMID 16308383.