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==Overview==
==Overview==
 
Enterobiasis is an infection caused commonly by Enterobius vermiculasis (pinworm). It usually affects children and causes perianal pruritis, restlessness, and irritability. The diagnosis is made by physical examination and repeated scotch-tape tests. This infection is medically treated by two doses of either pyrental pamoate, albendazole or mebendazole. Adopting healthy hygienic measures (frequent hand washing, changing clothes and covering food) and treating all the household members of the infected person can prevent the transmission of enterobiasis.


==Historical Perspective==
==Historical Perspective==

Revision as of 13:15, 21 June 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Furqan M M. M.B.B.S[2]

Overview

Enterobiasis is an infection caused commonly by Enterobius vermiculasis (pinworm). It usually affects children and causes perianal pruritis, restlessness, and irritability. The diagnosis is made by physical examination and repeated scotch-tape tests. This infection is medically treated by two doses of either pyrental pamoate, albendazole or mebendazole. Adopting healthy hygienic measures (frequent hand washing, changing clothes and covering food) and treating all the household members of the infected person can prevent the transmission of enterobiasis.

Historical Perspective

Enterobiasis vermicularis eggs found in western Utah are carbon dated to 7837 BC. In 1983, Jean-Pierre Hugot isolated a new species Enterobiasis gregorii which is identical to Enteobiasis vermicularis.

Classification

There is no known classification for enterobiasis but it may be classified on the basis of the organisms causing it; Enterobius vermicularis and Enterobius gregorri.

Pathophysiology

Enterobius vermicularis is usually transmitted via the feco-oral route to the human host. It reproduces in the small intestine of humans only. The gravid female worm lays eggs in the perianal area usually at night and causes pruritus. In addition to the fingernail contamination, the infective eggs can be transmitted via the dust and fomites.

Causes

The pinworm (genus Enterobius), also known as threadworm (in the United Kingdom and Australia) or seatworm, is a parasitic worm. It is a nematode (roundworm) and a common intestinal parasite or helminth, especially in humans.[1] The medical condition associated with pinworm infestation is known as enterobiasis[2] (a type of helminthiasis) or less precisely as oxyuriasis in reference to the family Oxyuridae.[3]

Differentiating (Disease name) from other Conditions

Enterobiasis must be differentiated from other nematode infections.

Epidemiology and Demographics

Enterobiasis is particularly common in children. Annually, around 200 million people are infected worldwide. The pinworm is the most common helminth (i.e., parasitic worm) infection in the United States and Western Europe.

Risk Factors

Common risk factors in the development of enterobiasis are young age, unhygienic practices, and close contact with infected person.

Natural History, Complications and Prognosis

If left untreated, patients with enterobiasis may progress to develop secondary skin infections. Common complications of enterobiasis include bacterial dermatitis, folliculitis, vulvovaginitis, and recurrent cystitis. Prognosis is generally excellent.

Diagnosis

History and Symptoms

The symptoms may include painful itching around the anus, restless sleep, poor appetite, and failure to gain weight. When the infection is heavy, there can be a secondary bacterial infection due to the irritation and scratching of the anal area.

Physical Examination

Patients with enterobiasis usually appear restless. Physical examination of patients with enterobiasis is remarkable for skin excoriations as a result of scratching (secondary to perianal itch), perianal skin infections, and visualization of adult worms in the perianal area; usually at night.[4][5]

Laboratory Findings

Diagnosis of enterobiasis is often made clinically by observing the female worm(s) in the peri-anal region, but can also be made using the "scotch-tape" test, in which the sticky side of a strip of cellophane tape is pressed against the peri-anal skin, then examined under a microscope for pinworm eggs.

Chest X Ray

The x-ray has no role in the diagnosis of the enterobiasis.

Echocardiography or Ultrasound

The USG has no role in the diagnosis of the enterobiasis.

Other Imaging Findings

There is no other imaging finding for the enterobiasis.

Treatment

Medical Therapy

Antiparasitic drugs used for enterobiasis include either mebendazole (Vermox), albendazole, piperazine (Antepar), or pyrantel pamoate (Combatrin, Povan). A repeat dose is recommended two weeks after the initial treatment. More than one household member is likely to be infected, so the entire household is often treated.

Surgery

Surgery has no role in the treatment of enterobiasis.

Prevention

Effective measures for the primary and secondary prevention of enterobiasis include treating family members, frequent handwashing, improving personal and household hygienic condition.

References

  1. Encyclopædia Britannica.
  2. Merriam-Webster: Enterobiasis
  3. Merriam-Webster: Oxyuriasis
  4. Cook GC (1994). "Enterobius vermicularis infection". Gut. 35 (9): 1159–62. PMC 1375686. PMID 7959218.
  5. Caldwell JP (1982). "Pinworms (enterobius vermicularis)". Can Fam Physician. 28: 306–9. PMC 2306321. PMID 21286054.

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