11β-hydroxylase deficiency natural history, complications and prognosis: Difference between revisions
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==Overview== | ==Overview== | ||
If left untreated, patients with congenital adrenal hyperplasia due to 11β-hydroxylase deficiency may progress to develop malignant hypertension. Common complications of congenital adrenal hyperplasia due to 11β-hydroxylase deficiency include muscle weakness, metabolic alkalosis, and azoospermia. Prognosis is generally good with treatment. | |||
==Natural History== | ==Natural History== | ||
If left untreated, patients with congenital adrenal hyperplasia due to 11β-hydroxylase deficiency may progress to develop malignant hypertension. | |||
==Complications== | ==Complications== | ||
===Complications of Hypertension=== | ===Complications of Hypertension=== | ||
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* Oligospermia | * Oligospermia | ||
* Infertility | * Infertility | ||
==Prognosis== | ==Prognosis== | ||
*The prognosis of congenital adrenal hyperplasia due to 11β-hydroxylase deficiency is generally good with treatment.<ref name="Wikipeadia">https://en.wikipedia.org/wiki/Congenital_adrenal_hyperplasia_due_to_21-hydroxylase_deficiency URL Accessed on 10/15/2015 </ref> | *The prognosis of congenital adrenal hyperplasia due to 11β-hydroxylase deficiency is generally good with treatment.<ref name="Wikipeadia">https://en.wikipedia.org/wiki/Congenital_adrenal_hyperplasia_due_to_21-hydroxylase_deficiency URL Accessed on 10/15/2015 </ref> |
Revision as of 19:02, 28 January 2016
Congenital adrenal hyperplasia due to 11β-hydroxylase deficiency Microchapters |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]
Overview
If left untreated, patients with congenital adrenal hyperplasia due to 11β-hydroxylase deficiency may progress to develop malignant hypertension. Common complications of congenital adrenal hyperplasia due to 11β-hydroxylase deficiency include muscle weakness, metabolic alkalosis, and azoospermia. Prognosis is generally good with treatment.
Natural History
If left untreated, patients with congenital adrenal hyperplasia due to 11β-hydroxylase deficiency may progress to develop malignant hypertension.
Complications
Complications of Hypertension
- Vascular hemorrhage
- Renal insufficiency
- Left ventricular hypertrophy
- Hypertensive retinopathy
- Stroke
Complications of Hypokalemia
- Muscle weakness
- Metabolic alkalosis
- Paralytic ileus
Other Complications
- Azoospermia
- Oligospermia
- Infertility
Prognosis
- The prognosis of congenital adrenal hyperplasia due to 11β-hydroxylase deficiency is generally good with treatment.[1]
- A small percentage of children and adults with infancy or childhood onset congenital adrenal hyperplasia die of adrenal crisis, even after diagnosis and initiation of treatment.
- When a person is well, missing a dose or even several doses, may not worsen the immediate symptoms. However, glucocorticoid needs are increased during illness and stress.
References
- ↑ https://en.wikipedia.org/wiki/Congenital_adrenal_hyperplasia_due_to_21-hydroxylase_deficiency URL Accessed on 10/15/2015