Mycosis fungoides classification: Difference between revisions

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|+ '''Cutaneous T cell lymphoma classification<ref name= seer.cancer> Cutaneous T cell lymphoma. Surveillance, Epidemiology, and End Results . http://seer.cancer.gov/seertools/hemelymph/51f6cf56e3e27c3994bd52f7/ Accessed on January 19, 2016</ref>'''
! style="background: #4479BA;; color:#FFF;" | Name
! style="background: #4479BA;; color:#FFF;" | Description
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| style="text-align: center; padding: 5px 5px; background: #F5F5F5;" | '''Primary or cutaneous CD8-positive aggressive epidermotropic cytotoxic T-cell lymphoma''' 
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* Characterized by localized or disseminated eruptive papules, nodules with tumors showing central ulceration, and necrosis or by superficial hyperkeratotic patches and plaques
* Dissemination to other visceral sites (lung, testis, CNS, and oral mucosa) possible
* Lymph nodes seldom affected
* Aggressive clinical course with median survival of 32 months
|-
| style="text-align: center; padding: 5px 5px; background: #F5F5F5;" | ''' Primary cutaneous CD4-positive small/medium T-cell lymphoma''' 
| style="padding: 5px 5px; background: #F5F5F5;" |
* Clinical presentation is usually a solitary plaque or nodule, commonly on the face, neck, or upper trunk
* Involvement of lower extremities is rare
* There should be an absence of patches
|}
==References==
==References==
{{reflist|2}}
{{reflist|2}}

Revision as of 16:02, 19 January 2016

Cutaneous T cell lymphoma Microchapters

Home

Patient Information

Overview

Classification

Mycosis fungoides
Sezary syndrome

Pathophysiology

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sowminya Arikapudi, M.B,B.S. [2]

Overview

Based on the organ involvement, cutaneous T cell lymphoma may be classified into mycosis fungoides (MF) and sézary syndrome (SS).[1]

Classification

Based on the organ involvement, cutaneous T cell lymphoma may be classified into:[1]

Cutaneous T cell lymphoma classification[1]
Name Description
Mycosis fungoides (MF)
  • Most common form of cutaneous T cell lymphoma
  • Starts in the skin in areas of the body not usually exposed to the sun
  • May appear as a scaly, pink or red rash or patches on the skin
  • Signs can progress to skin tumours in more advanced cases
Sézary syndrome (SS)
  • Often the more aggressive form of cutaneous T cell lymphoma
  • An advanced form of mycosis fungoides
  • Affects skin, blood, and lymph nodes
  • Large areas of the skin are affected
  • Skin is often red, itchy, painful and peeling
  • Skin tumours can also appear
  • Entire body can be affected, also known as "red man syndrome"


Cutaneous T cell lymphoma classification[2]
Name Description
Primary or cutaneous CD8-positive aggressive epidermotropic cytotoxic T-cell lymphoma
  • Characterized by localized or disseminated eruptive papules, nodules with tumors showing central ulceration, and necrosis or by superficial hyperkeratotic patches and plaques
  • Dissemination to other visceral sites (lung, testis, CNS, and oral mucosa) possible
  • Lymph nodes seldom affected
  • Aggressive clinical course with median survival of 32 months
Primary cutaneous CD4-positive small/medium T-cell lymphoma
  • Clinical presentation is usually a solitary plaque or nodule, commonly on the face, neck, or upper trunk
  • Involvement of lower extremities is rare
  • There should be an absence of patches

References

  1. 1.0 1.1 1.2 Cutaneous T cell lymphoma. Canadian Cancer Society. http://www.cancer.ca/en/cancer-information/cancer-type/non-hodgkin-lymphoma/non-hodgkin-lymphoma/types-of-nhl/cutaneous-t-cell-lymphoma/?region=on Accessed on January 19, 2016
  2. Cutaneous T cell lymphoma. Surveillance, Epidemiology, and End Results . http://seer.cancer.gov/seertools/hemelymph/51f6cf56e3e27c3994bd52f7/ Accessed on January 19, 2016


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