Cystic nephroma: Difference between revisions

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==Treatment==
==Treatment==
[[Cystic nephroma medical therapy|Medical therapy]] | [[Cystic nephroma surgery|Surgery]] | [[Cystic nephroma primary prevention|Primary prevention]]  | [[Cystic nephroma secondary prevention|Secondary prevention]] | [[Cystic nephroma cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Cystic nephroma future or investigational therapies|Future or Investigational Therapies]]
[[Cystic nephroma medical therapy|Medical therapy]] | [[Cystic nephroma surgery|Surgery]] | [[Cystic nephroma primary prevention|Primary prevention]]  | [[Cystic nephroma secondary prevention|Secondary prevention]] | [[Cystic nephroma cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Cystic nephroma future or investigational therapies|Future or Investigational Therapies]]
==Case Studies==
[[Cystic nephroma case study one|Case #1]]
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{{WS}}
[[Category:Disease]]
[[Category:Types of cancer]]
==Overview==
==Overview==
A '''cystic nephroma''', also known as '''multilocular cystic nephroma''', '''mixed epithelial stromal tumour (MEST)''' and '''renal epithelial stromal tumour (REST)''',<ref name=pmid17414095>{{cite journal  |vauthors=Turbiner J, Amin MB, Humphrey PA, etal |title=Cystic nephroma and mixed epithelial and stromal tumor of kidney: a detailed clinicopathologic analysis of 34 cases and proposal for renal epithelial and stromal tumor (REST) as a unifying term |journal=Am. J. Surg. Pathol. |volume=31 |issue=4 |pages=489–500 |date=April 2007 |pmid=17414095 |doi=10.1097/PAS.0b013e31802bdd56 |url=}}</ref> is a type of rare [[benign tumor|benign]] [[kidney tumour]].
A '''cystic nephroma''', also known as '''multilocular cystic nephroma''', '''mixed epithelial stromal tumour (MEST)''' and '''renal epithelial stromal tumour (REST)''',<ref name=pmid17414095>{{cite journal  |vauthors=Turbiner J, Amin MB, Humphrey PA, etal |title=Cystic nephroma and mixed epithelial and stromal tumor of kidney: a detailed clinicopathologic analysis of 34 cases and proposal for renal epithelial and stromal tumor (REST) as a unifying term |journal=Am. J. Surg. Pathol. |volume=31 |issue=4 |pages=489–500 |date=April 2007 |pmid=17414095 |doi=10.1097/PAS.0b013e31802bdd56 |url=}}</ref> is a type of rare [[benign tumor|benign]] [[kidney tumour]].

Revision as of 17:40, 29 October 2015

Cystic nephroma Microchapters

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Overview

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Synonyms and keywords:

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Cystic nephroma

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Staging | History and Symptoms | Physical Examination | Laboratory Findings | X Ray | CT | MRI Ultrasound | Other Imaging Findings | Other Diagnostic Studies | Biopsy

Treatment

Medical therapy | Surgery | Primary prevention | Secondary prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

Case Studies

Case #1

Template:WH Template:WS



Overview

A cystic nephroma, also known as multilocular cystic nephroma, mixed epithelial stromal tumour (MEST) and renal epithelial stromal tumour (REST),[1] is a type of rare benign kidney tumour.

Symptoms

Cystic nephromas are often asymptomatic. They are typically discovered on medical imaging incidentally (i.e. an incidentaloma).

Diagnosis

Cystic nephromas are diagnosed by biopsy or excision. It is important to correctly diagnose them as, radiologically, they may mimic the appearance of a renal cell carcinoma that is cystic.[2]

Pathologic diagnosis

High magnification micrograph of a cystic nephroma showing the characteristic simple epithelium with hobnail morphology, and the ovarian-like stroma. H&E stain.

The characteristics of cystic nephromas are:

  • Cysts lined by a simple epithelium with a hobnail morphology, i.e. the nuclei of the cyst lining epithelium bulges into the lumen of the cysts,
  • Ovarian-like stroma that has a:

Cystic nephromas have an immunostaining pattern like ovarian stroma; they are positive for:

Differential diagnosis

References

  1. Turbiner J, Amin MB, Humphrey PA, et al. (April 2007). "Cystic nephroma and mixed epithelial and stromal tumor of kidney: a detailed clinicopathologic analysis of 34 cases and proposal for renal epithelial and stromal tumor (REST) as a unifying term". Am. J. Surg. Pathol. 31 (4): 489–500. doi:10.1097/PAS.0b013e31802bdd56. PMID 17414095.
  2. Small JE et al. Cystic Nephroma. BrighamRAD Teaching Case Database. URL: http://brighamrad.harvard.edu/Cases/bwh/hcache/385/full.html. Accessed: July 25, 2009.

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