Insulinoma pathophysiology: Difference between revisions
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Pancreatic insulinoma histology 2.JPG|Histopathology of pancreatic endocrine tumor (insulinoma)<ref name=123> Neuroendocrine tumour of the pancreas. Libre Pathology. http://librepathology.org/wiki/index.php/Neuroendocrine_tumour_of_the_pancreas Accessed on September, 30 2015</ref> | Pancreatic insulinoma histology 2.JPG|Histopathology of pancreatic endocrine tumor (insulinoma)<ref name=123> Neuroendocrine tumour of the pancreas. Libre Pathology. http://librepathology.org/wiki/index.php/Neuroendocrine_tumour_of_the_pancreas Accessed on September, 30 2015</ref> | ||
Pancreatic insulinoma histopathology 3.JPG|Histopathology of pancreatic endocrine tumor (insulinoma). Chromogranin A immunostain<ref name=123> Neuroendocrine tumour of the pancreas. Libre Pathology. http://librepathology.org/wiki/index.php/Neuroendocrine_tumour_of_the_pancreas Accessed on September, 30 2015</ref> | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
Revision as of 17:31, 1 October 2015
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Insulinoma Microchapters |
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Insulinoma pathophysiology On the Web |
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Risk calculators and risk factors for Insulinoma pathophysiology |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Parminder Dhingra, M.D. [2]
Overview
Pathophysiology
- Insulinoma can occur in association with inherited syndrome, such as multiple endocrine neoplasia type 1 or sporadic.[1]
- Multiple endocrine neoplasia type 1 is an autosomal dominant disorder caused by alterations of the MEN1 gene located at chromosomal region 11q13.
- Approximately 10% of insulinomas are multiple and 10% malignant.[2]
<gallery widths=200px>
Pancreatic insulinoma Histology 1.JPG|Histopathology of pancreatic endocrine tumor (insulinoma). H&E stain
Pancreatic insulinoma histology 2.JPG|Histopathology of pancreatic endocrine tumor (insulinoma)
Pancreatic insulinoma histopathology 3.JPG|Histopathology of pancreatic endocrine tumor (insulinoma). Chromogranin A immunostain
References
- ↑ Murray PD, McKenzie DT, Swain SL, Kagnoff MF (1987). "Interleukin 5 and interleukin 4 produced by Peyer's patch T cells selectively enhance immunoglobulin A expression". J Immunol. 139 (8): 2669–74. PMID 3498768.
- ↑ Insulinoma. Dr Yuranga Weerakkody and Dr Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/insulinoma