Glioma medical therapy: Difference between revisions
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{{Glioma}} | {{Glioma}} | ||
{{CMG}}; '''Associate Editor-In-Chief:''' {{CZ}} | {{CMG}}; '''Associate Editor-In-Chief:''' {{CZ}}, {{SR}} | ||
==Overview== | ==Overview== | ||
Treatment for brain glioma depends on the location and grade. The predominant therapy for glioma is [[surgical resection]]. Adjunctive [[chemotherapy]] and [[radiation]] may be required.<ref name=ddd>Treatment of glioblastoma multiforme. Dr Dylan Kurda and Dr Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/glioblastoma</ref> | |||
==Medical Therapy== | |||
The predominant therapy for glioma is [[surgical resection]]. Adjunctive [[chemotherapy]] and [[radiation]] may be required.<ref name=ddd>Treatment of glioblastoma multiforme. Dr Dylan Kurda and Dr Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/glioblastoma</ref> | |||
===Radiotherapy=== | |||
*After [[surgery]], [[radiotherapy]] is recommended among all patients who develop glioma. | |||
*Radiotherapy may not cure the cancer, but can control the tumor and delay recurrence. | |||
*Targeted three-dimensional conformal [[radiotherapy]] is preferred to whole brain radiotherapy. | |||
*Total [[radiation]] dose of 60–65 Gy has been found to be optimal for treatment. | |||
===Chemotherapy=== | |||
*[[Chemotherapy]] is indicated as adjuvant therapy for glioma. | |||
*[[Temozolomide]] ([[Temodar]]) is the preferred drug for the treatment of glioma as it easily penetrates the blood brain barrier. | |||
*Other chemotherapeutic drugs that may be used for the treatment of glioblastoma multiforme include: | |||
**[[Carmustine]] | |||
**[[Lomustine]] | |||
**[[Vincristine]] | |||
**[[Cisplatin]] | |||
**[[Erlotinib]] | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
Revision as of 14:18, 23 September 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief: Cafer Zorkun, M.D., Ph.D. [2], Sujit Routray, M.D. [3]
Overview
Treatment for brain glioma depends on the location and grade. The predominant therapy for glioma is surgical resection. Adjunctive chemotherapy and radiation may be required.[1]
Medical Therapy
The predominant therapy for glioma is surgical resection. Adjunctive chemotherapy and radiation may be required.[1]
Radiotherapy
- After surgery, radiotherapy is recommended among all patients who develop glioma.
- Radiotherapy may not cure the cancer, but can control the tumor and delay recurrence.
- Targeted three-dimensional conformal radiotherapy is preferred to whole brain radiotherapy.
- Total radiation dose of 60–65 Gy has been found to be optimal for treatment.
Chemotherapy
- Chemotherapy is indicated as adjuvant therapy for glioma.
- Temozolomide (Temodar) is the preferred drug for the treatment of glioma as it easily penetrates the blood brain barrier.
- Other chemotherapeutic drugs that may be used for the treatment of glioblastoma multiforme include:
References
- ↑ 1.0 1.1 Treatment of glioblastoma multiforme. Dr Dylan Kurda and Dr Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/glioblastoma