Tramazoline: Difference between revisions

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{{Incomplete|date=January 2015}}
{{Drugbox
{{Drugbox
| IUPAC_name       = N-(5,6,7,8-tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazol-2-amine
| Verifiedfields = changed
| image             = Tramazoline.png
| Watchedfields = changed
| CAS_number        =
| verifiedrevid = 457287903
| ATC_prefix        = R01
| IUPAC_name = ''N''-(5,6,7,8-tetrahydronaphthalen-1-yl)-4,5-dihydro-1''H''-imidazol-2-amine
| ATC_suffix        = AA09
| image = Tramazoline.png
| PubChem          = 5524
| DrugBank          =
| C=13|H=17|N=3
| molecular_weight  = 215.294 g/mol
| bioavailability  =
| protein_bound    =
| metabolism        =
| elimination_half-life =
| excretion        =
| pregnancy_AU      =  <!-- A / B1 / B2 / B3 / C / D / X -->
| pregnancy_US      =  <!-- A / B            / C / D / X -->
| pregnancy_category= 
| legal_AU          =  <!-- Unscheduled / S2 / S3 / S4 / S5 / S6 / S7 / S8 / S9 -->
| legal_CA          =  <!--            / Schedule I, II, III, IV, V, VI, VII, VIII -->
| legal_UK          =  <!-- GSL        / P      / POM / CD / Class A, B, C -->
| legal_US          =  <!-- OTC                  / Rx-only  / Schedule I, II, III, IV, V -->
| legal_status      =
| routes_of_administration =
}}
{{CMG}}


<!--Clinical data-->
| tradename = 
| Drugs.com = {{drugs.com|international|tramazoline}}
| pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X -->
| pregnancy_US = <!-- A / B            / C / D / X -->
| pregnancy_category = 
| legal_AU = <!-- Unscheduled / S2 / S3 / S4 / S5 / S6 / S7 / S8 / S9 -->
| legal_CA = <!--            / Schedule I, II, III, IV, V, VI, VII, VIII -->
| legal_UK = <!-- GSL        / P      / POM / CD / Class A, B, C -->
| legal_US = <!-- OTC                  / Rx-only  / Schedule I, II, III, IV, V -->
| legal_status = 
| routes_of_administration = 


<!--Pharmacokinetic data-->
| bioavailability = 
| protein_bound = 
| metabolism = 
| elimination_half-life = 
| excretion = 


'''Tramazoline''' is a nasal preparation.
<!--Identifiers-->
| CAS_number_Ref = {{cascite|changed|??}}
| CAS_number = 1082-57-1
| ATC_prefix = R01
| ATC_suffix = AA09
| PubChem = 5524
| DrugBank_Ref = {{drugbankcite|correct|drugbank}}
| DrugBank = 
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = SLE31693IV
| ChEMBL_Ref = {{ebicite|changed|EBI}}
| ChEMBL = 32573


{{Nasal preparations}}
<!--Chemical data-->
 
| C=13 | H=17 | N=3
[[Category:Imidazolines]]
| molecular_weight = 215.294 g/mol
}}
'''Tramazoline''' is a chemical that is used in the form of '''tramazoline hydrochloride''' in nasal decongestant preparations. <ref>{{cite web|first=Boehringer Ingelheim|title=Spray-Tish Consumer Information|url=http://www.mydr.com.au/medicines/cmis/spray-tish-nasal-spray|work=Consumer Medicines Information|publisher=MyDr.com.au|accessdate=16 April 2011}}</ref> It is an α-adrenergic receptor agonist that inhibits secretion of nasal mucus.


{{WH}}
It causes [[hypertension]].<ref name="pmid7721439">{{cite journal |author=Peng N, Meng QC, King K, Oparil S, Wyss JM |title=Acute hypertension increases norepinephrine release in the anterior hypothalamic area |journal=Hypertension |volume=25 |issue=4 Pt 2 |pages=828–33 |date=April 1995 |pmid=7721439 |doi= 10.1161/01.hyp.25.4.828|url=http://hyper.ahajournals.org/cgi/pmidlookup?view=long&pmid=7721439}}</ref>
{{WS}}

Revision as of 18:37, 10 April 2015

Template:Incomplete

Tramazoline
Clinical data
AHFS/Drugs.comInternational Drug Names
ATC code
Identifiers
CAS Number
PubChem CID
UNII
ChEMBL
E number{{#property:P628}}
ECHA InfoCard{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
FormulaC13H17N3
Molar mass215.294 g/mol
 ☒N☑Y (what is this?)  (verify)

Tramazoline is a chemical that is used in the form of tramazoline hydrochloride in nasal decongestant preparations. [1] It is an α-adrenergic receptor agonist that inhibits secretion of nasal mucus.

It causes hypertension.[2]

  1. ↑ "Spray-Tish Consumer Information". Consumer Medicines Information. MyDr.com.au. Retrieved 16 April 2011. |first1= missing |last1= in Authors list (help)
  2. ↑ Peng N, Meng QC, King K, Oparil S, Wyss JM (April 1995). "Acute hypertension increases norepinephrine release in the anterior hypothalamic area". Hypertension. 25 (4 Pt 2): 828–33. doi:10.1161/01.hyp.25.4.828. PMID 7721439.
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