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! style="background: #4479BA; color:#FFF;  width: 350px;" | Disease
! style="background: #4479BA; color:#FFF;  width: 350px;" | Disease
! style="background: #4479BA; color:#FFF;  width: 350px;" | Description
! style="background: #4479BA; color:#FFF;  width: 350px;" | Clinical Findings
! style="background: #4479BA; color:#FFF;  width: 350px;" | Clinical Findings
! style="background: #4479BA; color:#FFF;  width: 350px;" | Diagnosis  
! style="background: #4479BA; color:#FFF;  width: 350px;" | Diagnosis  
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! style="background: #4479BA; color:#FFF;  width: 350px;" | Treatment
! style="background: #4479BA; color:#FFF;  width: 350px;" | Treatment
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| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" | Pneumocystis Pneumonia
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" | [[Pneumocystis Pneumonia]]
| style="padding: 5px 5px; background: #F5F5F5;" | Subacute onset of progressive dyspnea, fever, nonproductive cough, and chest discomfort that worsens within days to weeks. Tachypnea, tachycardia, and diffuse dry rales.  
| style="padding: 5px 5px; background: #F5F5F5;" |
*Caused by the fungus ''Pneumocystis jirovecii''.
*90% of cases occurred among patients with CD4+ <200
*Incidence among HIV patients: 2-3 cases per 100 person-year
| style="padding: 5px 5px; background: #F5F5F5;" |Subacute onset of progressive dyspnea, fever, nonproductive cough, and chest discomfort that worsens within days to weeks. Tachypnea, tachycardia, and diffuse dry rales are found in the physical examination.
| style="padding: 5px 5px; background: #F5F5F5;" | Clinical presentation, blood tests, or chest x-rays are not pathognomonic for PCP.
| style="padding: 5px 5px; background: #F5F5F5;" | Clinical presentation, blood tests, or chest x-rays are not pathognomonic for PCP.
| style="padding: 5px 5px; background: #F5F5F5;" | Start TMP-SMX prophylaxys when CD4+ <200 cells/µL or a history of oropharyngeal candidiasis  
| style="padding: 5px 5px; background: #F5F5F5;" | Start TMP-SMX prophylaxys when CD4+ <200 cells/µL or history of oropharyngeal candidiasis.  <br> Discontinue prohylaxys when  CD4+ is >200 cells/µL for >3 month.
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| style="padding: 5px 5px; background: #F5F5F5;" |  
*TMP-SMX
*<small>Administer adjunctive corticosteroids in patients with pO2 <70 mm Hg or arterial-alveolar O2 gradient >35 mm Hg</small>
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| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" | Toxoplasma gondii Encephalitis
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" | [[Toxoplasma gondii]] Encephalitis
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Revision as of 20:08, 14 October 2014

Disease Description Clinical Findings Diagnosis Prophylaxis Treatment
Pneumocystis Pneumonia
  • Caused by the fungus Pneumocystis jirovecii.
  • 90% of cases occurred among patients with CD4+ <200
  • Incidence among HIV patients: 2-3 cases per 100 person-year
Subacute onset of progressive dyspnea, fever, nonproductive cough, and chest discomfort that worsens within days to weeks. Tachypnea, tachycardia, and diffuse dry rales are found in the physical examination. Clinical presentation, blood tests, or chest x-rays are not pathognomonic for PCP. Start TMP-SMX prophylaxys when CD4+ <200 cells/µL or history of oropharyngeal candidiasis.
Discontinue prohylaxys when CD4+ is >200 cells/µL for >3 month.
  • TMP-SMX
  • Administer adjunctive corticosteroids in patients with pO2 <70 mm Hg or arterial-alveolar O2 gradient >35 mm Hg
Toxoplasma gondii Encephalitis
Cryptosporidiosis
Microsporidiosis
Mycobacterium tuberculosis
Table adapted from Guidelines for Prevention and Treatment of Opportunistic Infections in HIV-Infected Adults and Adolescents [1]
  1. "Guidelines for Prevention and Treatment of Opportunistic Infections in HIV-Infected Adults and Adolescents".