Prazosin dosage and administration: Difference between revisions

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#REDIRECT [[Prazosin#Adult Indications and Dosage]]
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==Dosage and Administration==
 
The dose of MINIPRESS should be adjusted according to the patient's individual blood pressure response. The following is a guide to its administration:
 
===Initial Dose===
 
1 mg two or three times a day (see [[Prazosin warnings|WARNINGS]].)
===Maintenance Dose===
 
Dosage may be slowly increased to a total daily dose of 20 mg given in divided doses. The therapeutic dosages most commonly employed have ranged from 6 mg to 15 mg daily given in divided doses. Doses higher than 20 mg usually do not increase efficacy, however a few patients may benefit from further increases up to a daily dose of 40 mg given in divided doses. After initial titration some patients can be maintained adequately on a twice daily dosage regimen.
 
===Use With Other Drugs===
 
When adding a diuretic or other antihypertensive agent, the dose of MINIPRESS should be reduced to 1 mg or 2 mg three times a day and retitration then carried out.
 
Concomitant administration of MINIPRESS with a PDE-5 inhibitor can result in additive blood pressure lowering effects and symptomatic hypotension; therefore, PDE-5 inhibitor therapy should be initiated at the lowest dose in patients taking MINIPRESS.<ref name="dailymed.nlm.nih.gov">{{Cite web  | last =  | first =  | title = MINIPRESS (PRAZOSIN HYDROCHLORIDE) CAPSULE [PFIZER LABORATORIES DIV PFIZER INC] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=36c4da56-502e-4da1-acf7-8e81ee453dcc | publisher =  | date =  | accessdate = 6 March 2014 }}</ref>
 
 
 
==References==
 
{{Reflist|2}}
 
[[Category:Cardiovascular Drugs]]
[[Category:Drugs]]

Latest revision as of 23:12, 21 July 2014