Amitriptyline: Difference between revisions

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==Overview==
==Overview==


 
'''Amitriptyline''' ('''Elavil''', '''Endep''', '''Levate''' and [[Amitriptyline#Brand_names|many others]]) is a [[tricyclic antidepressant]] (TCA). It is the most widely used TCA and is an efficacious treatment for [[major depressive disorder]] (clinical depression). It was originally developed by [[Merck & Co.|Merck]] and was initially approved by the [[United States]] [[Food and Drug Administration]] (FDA) on 7 April 1961.<ref name="pmid18204333">{{cite journal | author = Fangmann P, Assion HJ, Juckel G, González CA, López-Muñoz F | title = Half a century of antidepressant drugs: on the clinical introduction of monoamine oxidase inhibitors, tricyclics, and tetracyclics. Part II: tricyclics and tetracyclics | journal = Journal of Clinical Psychopharmacology |volume = 28 | issue = 1 | pages = 1–4 |date=February 2008 | pmid = 18204333 | doi = 10.1097/jcp.0b013e3181627b60 | url =http://meta.wkhealth.com/pt/pt-core/template-journal/lwwgateway/media/landingpage.htm?issn=0271-0749&volume=28&issue=1&spage=1}}</ref>


==Category==
==Category==

Revision as of 01:35, 10 February 2014

Amitriptyline
AMITRIPTYLINE HYDROCHLORIDE®
FDA Package Insert
Indications and Usage
Dosage and Administration
Contraindications
Warnings and Precautions
Adverse Reactions
Drug Interactions
Use in Specific Populations
Overdosage
Description
Clinical Pharmacology
How Supplied/Storage and Handling
Patient Counseling Information
Labels and Packages
Clinical Trials on Amitriptyline
ClinicalTrials.gov

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

For patient information about Amitriptyline, click here.

Synonyms / Brand Names: Amitriptyline Hydrochloride, Amitriptyline HCL, Amitriprolidine, Amitriptylin, Amitryptiline, Amitryptyline, Amytriptiline, Adepress, Adepril, Amitid, Amitril, Damilan, Damilen, dAmitriptyline, Elanil, Elavil, Endep, Flavyl, Hexathane, Horizon, Lantron, Laroxil, Laroxyl, Lentizol, Proheptadiene, Redomex, Saroten, Sarotex, Seroten, Sylvemid, Triptanol, Triptilin, Triptisol, Tryptanol, Tryptizol

Overview

Amitriptyline (Elavil, Endep, Levate and many others) is a tricyclic antidepressant (TCA). It is the most widely used TCA and is an efficacious treatment for major depressive disorder (clinical depression). It was originally developed by Merck and was initially approved by the United States Food and Drug Administration (FDA) on 7 April 1961.[1]

Category

Antidepressants

FDA Package Insert

AMITRIPTYLINE HYDROCHLORIDE tablet, film coated

Indications and Usage | Dosage and Administration | Dosage Forms and Strengths | Contraindications | Warnings and Precautions | Adverse Reactions | Drug Interactions | Use in Specific Populations | Overdosage | Description | Clinical Pharmacology | Nonclinical Toxicology | Clinical Studies | How Supplied/Storage and Handling | Patient Counseling Information | Labels and Packages

Mechanism of Action

References

  1. Fangmann P, Assion HJ, Juckel G, González CA, López-Muñoz F (February 2008). "Half a century of antidepressant drugs: on the clinical introduction of monoamine oxidase inhibitors, tricyclics, and tetracyclics. Part II: tricyclics and tetracyclics". Journal of Clinical Psychopharmacology. 28 (1): 1–4. doi:10.1097/jcp.0b013e3181627b60. PMID 18204333.