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{{Infobox_gene}}
{{PBB_Controls
'''Peroxisome assembly protein 12''' is a [[protein]] that in humans is encoded by the ''PEX12'' [[gene]].<ref name="pmid9090384">{{cite journal | vauthors = Chang CC, Lee WH, Moser H, Valle D, Gould SJ | title = Isolation of the human PEX12 gene, mutated in group 3 of the peroxisome biogenesis disorders | journal = Nat Genet | volume = 15 | issue = 4 | pages = 385–8 |date=April 1997 | pmid = 9090384 | pmc = | doi = 10.1038/ng0497-385 }}</ref><ref name="entrez"/>
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}


<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
== Function ==
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Peroxisomal biogenesis factor 12
| HGNCid = 8854
| Symbol = PEX12
| AltSymbols =;
| OMIM = 601758
| ECnumber = 
| Homologene = 240
| MGIid = 2144177
| GeneAtlas_image1 = PBB_GE_PEX12_205094_at_tn.png
| Function = {{GNF_GO|id=GO:0005515 |text = protein binding}} {{GNF_GO|id=GO:0008270 |text = zinc ion binding}}
| Component = {{GNF_GO|id=GO:0005777 |text = peroxisome}} {{GNF_GO|id=GO:0005779 |text = integral to peroxisomal membrane}} {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
| Process = {{GNF_GO|id=GO:0016558 |text = protein import into peroxisome matrix}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 5193
    | Hs_Ensembl = ENSG00000108733
    | Hs_RefseqProtein = NP_000277
    | Hs_RefseqmRNA = NM_000286
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 17
    | Hs_GenLoc_start = 30925928
    | Hs_GenLoc_end = 30929695
    | Hs_Uniprot = O00623
    | Mm_EntrezGene = 103737
    | Mm_Ensembl = ENSMUSG00000018733
    | Mm_RefseqmRNA = NM_134025
    | Mm_RefseqProtein = NP_598786
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 11
    | Mm_GenLoc_start = 83110840
    | Mm_GenLoc_end = 83115172
    | Mm_Uniprot = Q3TLN1
  }}
}}
'''Peroxisomal biogenesis factor 12''', also known as '''PEX12''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: PEX12 peroxisomal biogenesis factor 12| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5193| accessdate = }}</ref>


<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
PEX12 is needed for protein import into peroxisomes.<ref name="pmid9632816">{{cite journal | vauthors = Okumoto K, Shimozawa N, Kawai A, Tamura S, Tsukamoto T, Osumi T, Moser H, Wanders RJ, Suzuki Y, Kondo N, Fujiki Y | title = PEX12, the pathogenic gene of group III Zellweger syndrome: cDNA cloning by functional complementation on a CHO cell mutant, patient analysis, and characterization of PEX12p | journal = Mol. Cell. Biol. | volume = 18 | issue = 7 | pages = 4324–36 |date=July 1998 | pmid = 9632816 | pmc = 109016 | doi = }}</ref> This gene belongs to the peroxin-12 family. [[Peroxin]]s (PEXs) are proteins that are essential for the assembly of functional peroxisomes.
{{PBB_Summary
 
| section_title =  
== Clinical significance ==
| summary_text = The peroxisome biogenesis disorders (PBDs; MIM 601539) are a group of genetically heterogeneous diseases that are usually lethal in early infancy. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. This cellular phenotype is shared by yeast 'pex' mutants, and human orthologs of yeast PEX genes defective in some PBD complementation groups (CGs).[supplied by OMIM]<ref name="entrez">{{cite web | title = Entrez Gene: PEX12 peroxisomal biogenesis factor 12| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5193| accessdate = }}</ref>
 
}}
The [[peroxisome biogenesis disorder]]s (PBDs; MIM 601539) are a group of genetically heterogeneous diseases that are usually lethal in early infancy. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. This cellular phenotype is shared by yeast 'pex' mutants, and human orthologs of yeast PEX genes defective in some PBD complementation groups (CGs).<ref name="entrez">{{cite web | title = Entrez Gene: PEX12 peroxisomal biogenesis factor 12| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5193| accessdate = }}</ref>
 
==Interactions==
PEX12 has been shown to [[Protein-protein interaction|interact]] with [[PEX10]],<ref name="pmid10562279">{{cite journal | vauthors = Chang CC, Warren DS, Sacksteder KA, Gould SJ | title = PEX12 interacts with PEX5 and PEX10 and acts downstream of receptor docking in peroxisomal matrix protein import | journal = J. Cell Biol. | volume = 147 | issue = 4 | pages = 761–74 |date=November 1999 | pmid = 10562279 | doi = 10.1083/jcb.147.4.761 |pmc=2156163 }}</ref><ref name="pmid10837480">{{cite journal | vauthors = Okumoto K, Abe I, Fujiki Y | title = Molecular anatomy of the peroxin Pex12p: ring finger domain is essential for Pex12p function and interacts with the peroxisome-targeting signal type 1-receptor Pex5p and a ring peroxin, Pex10p | journal = J. Biol. Chem. | volume = 275 | issue = 33 | pages = 25700–10 |date=August 2000 | pmid = 10837480 | doi = 10.1074/jbc.M003303200 }}</ref> [[PEX5]]<ref name=pmid10562279/><ref name=pmid10837480/> and [[PEX19]].<ref name="pmid10704444">{{cite journal | vauthors = Sacksteder KA, Jones JM, South ST, Li X, Liu Y, Gould SJ | title = PEX19 binds multiple peroxisomal membrane proteins, is predominantly cytoplasmic, and is required for peroxisome membrane synthesis | journal = J. Cell Biol. | volume = 148 | issue = 5 | pages = 931–44 |date=March 2000 | pmid = 10704444 | pmc = 2174547 | doi = 10.1083/jcb.148.5.931 }}</ref><ref name="pmid11390669">{{cite journal | vauthors = Fransen M, Wylin T, Brees C, Mannaerts GP, Van Veldhoven PP | title = Human pex19p binds peroxisomal integral membrane proteins at regions distinct from their sorting sequences | journal = Mol. Cell. Biol. | volume = 21 | issue = 13 | pages = 4413–24 |date=July 2001 | pmid = 11390669 | pmc = 87101 | doi = 10.1128/MCB.21.13.4413-4424.2001 }}</ref>


==References==
==References==
{{reflist|2}}
{{Reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{Refbegin | 2}}
{{PBB_Further_reading
*{{Cite journal  | vauthors=Okumoto K, Fujiki Y |title=PEX12 encodes an integral membrane protein of peroxisomes |journal=Nat. Genet. |volume=17 |issue= 3 |pages= 265–6 |year= 1997 |pmid= 9354782 |doi= 10.1038/ng1197-265 }}
| citations =
*{{Cite journal   |vauthors=Schrader M, Reuber BE, Morrell JC, etal |title=Expression of PEX11beta mediates peroxisome proliferation in the absence of extracellular stimuli |journal=J. Biol. Chem. |volume=273 |issue= 45 |pages= 29607–14 |year= 1998 |pmid= 9792670 |doi=10.1074/jbc.273.45.29607 }}
*{{cite journal  | author=Chang CC, Lee WH, Moser H, ''et al.'' |title=Isolation of the human PEX12 gene, mutated in group 3 of the peroxisome biogenesis disorders. |journal=Nat. Genet. |volume=15 |issue= 4 |pages= 385-8 |year= 1997 |pmid= 9090384 |doi= 10.1038/ng0497-385 }}
*{{Cite journal  | vauthors=Chang CC, Gould SJ |title=Phenotype-genotype relationships in complementation group 3 of the peroxisome-biogenesis disorders |journal=Am. J. Hum. Genet. |volume=63 |issue= 5 |pages= 1294–306 |year= 1998 |pmid= 9792857 |doi=10.1086/302103  | pmc=1377540 }}
*{{cite journal  | author=Okumoto K, Fujiki Y |title=PEX12 encodes an integral membrane protein of peroxisomes. |journal=Nat. Genet. |volume=17 |issue= 3 |pages= 265-6 |year= 1997 |pmid= 9354782 |doi= 10.1038/ng1197-265 }}
*{{Cite journal  | vauthors=South ST, Gould SJ |title=Peroxisome Synthesis in the Absence of Preexisting Peroxisomes |journal=J. Cell Biol. |volume=144 |issue= 2 |pages= 255–66 |year= 1999 |pmid= 9922452 |doi=10.1083/jcb.144.2.255  | pmc=2132891 }}
*{{cite journal  | author=Okumoto K, Shimozawa N, Kawai A, ''et al.'' |title=PEX12, the pathogenic gene of group III Zellweger syndrome: cDNA cloning by functional complementation on a CHO cell mutant, patient analysis, and characterization of PEX12p. |journal=Mol. Cell. Biol. |volume=18 |issue= 7 |pages= 4324-36 |year= 1998 |pmid= 9632816 |doi=  }}
*{{Cite journal  | vauthors=Chang CC, Warren DS, Sacksteder KA, Gould SJ |title=Pex12 Interacts with Pex5 and Pex10 and Acts Downstream of Receptor Docking in Peroxisomal Matrix Protein Import |journal=J. Cell Biol. |volume=147 |issue= 4 |pages= 761–74 |year= 1999 |pmid= 10562279 |doi=10.1083/jcb.147.4.761  | pmc=2156163 }}
*{{cite journal | author=Schrader M, Reuber BE, Morrell JC, ''et al.'' |title=Expression of PEX11beta mediates peroxisome proliferation in the absence of extracellular stimuli. |journal=J. Biol. Chem. |volume=273 |issue= 45 |pages= 29607-14 |year= 1998 |pmid= 9792670 |doi=  }}
*{{Cite journal   |vauthors=Sacksteder KA, Jones JM, South ST, etal |title=Pex19 Binds Multiple Peroxisomal Membrane Proteins, Is Predominantly Cytoplasmic, and Is Required for Peroxisome Membrane Synthesis |journal=J. Cell Biol. |volume=148 |issue= 5 |pages= 931–44 |year= 2000 |pmid= 10704444 |doi=10.1083/jcb.148.5.931  | pmc=2174547 }}
*{{cite journal  | author=Chang CC, Gould SJ |title=Phenotype-genotype relationships in complementation group 3 of the peroxisome-biogenesis disorders. |journal=Am. J. Hum. Genet. |volume=63 |issue= 5 |pages= 1294-306 |year= 1998 |pmid= 9792857 |doi=  }}
*{{Cite journal  | vauthors=Okumoto K, Abe I, Fujiki Y |title=Molecular anatomy of the peroxin Pex12p: ring finger domain is essential for Pex12p function and interacts with the peroxisome-targeting signal type 1-receptor Pex5p and a ring peroxin, Pex10p |journal=J. Biol. Chem. |volume=275 |issue= 33 |pages= 25700–10 |year= 2000 |pmid= 10837480 |doi= 10.1074/jbc.M003303200 }}
*{{cite journal  | author=South ST, Gould SJ |title=Peroxisome synthesis in the absence of preexisting peroxisomes. |journal=J. Cell Biol. |volume=144 |issue= 2 |pages= 255-66 |year= 1999 |pmid= 9922452 |doi=  }}
*{{Cite journal   |vauthors=Fransen M, Wylin T, Brees C, etal |title=Human Pex19p Binds Peroxisomal Integral Membrane Proteins at Regions Distinct from Their Sorting Sequences |journal=Mol. Cell. Biol. |volume=21 |issue= 13 |pages= 4413–24 |year= 2001 |pmid= 11390669 |doi= 10.1128/MCB.21.13.4413-4424.2001 | pmc=87101 }}
*{{cite journal  | author=Chang CC, Warren DS, Sacksteder KA, Gould SJ |title=PEX12 interacts with PEX5 and PEX10 and acts downstream of receptor docking in peroxisomal matrix protein import. |journal=J. Cell Biol. |volume=147 |issue= 4 |pages= 761-74 |year= 1999 |pmid= 10562279 |doi=  }}
*{{Cite journal   |vauthors=Fransen M, Brees C, Ghys K, etal |title=Analysis of mammalian peroxin interactions using a non-transcription-based bacterial two-hybrid assay |journal=Mol. Cell. Proteomics |volume=1 |issue= 3 |pages= 243–52 |year= 2002 |pmid= 12096124 |doi=10.1074/mcp.M100025-MCP200 }}
*{{cite journal | author=Sacksteder KA, Jones JM, South ST, ''et al.'' |title=PEX19 binds multiple peroxisomal membrane proteins, is predominantly cytoplasmic, and is required for peroxisome membrane synthesis. |journal=J. Cell Biol. |volume=148 |issue= 5 |pages= 931-44 |year= 2000 |pmid= 10704444 |doi=  }}
*{{Cite journal  | vauthors=Harper CC, Berg JM, Gould SJ |title=PEX5 binds the PTS1 independently of Hsp70 and the peroxin PEX12 |journal=J. Biol. Chem. |volume=278 |issue= 10 |pages= 7897–901 |year= 2003 |pmid= 12456682 |doi= 10.1074/jbc.M206651200 }}
*{{cite journal  | author=Okumoto K, Abe I, Fujiki Y |title=Molecular anatomy of the peroxin Pex12p: ring finger domain is essential for Pex12p function and interacts with the peroxisome-targeting signal type 1-receptor Pex5p and a ring peroxin, Pex10p. |journal=J. Biol. Chem. |volume=275 |issue= 33 |pages= 25700-10 |year= 2000 |pmid= 10837480 |doi= 10.1074/jbc.M003303200 }}
*{{Cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
*{{cite journal | author=Fransen M, Wylin T, Brees C, ''et al.'' |title=Human pex19p binds peroxisomal integral membrane proteins at regions distinct from their sorting sequences. |journal=Mol. Cell. Biol. |volume=21 |issue= 13 |pages= 4413-24 |year= 2001 |pmid= 11390669 |doi= 10.1128/MCB.21.13.4413-4424.2001 }}
*{{Cite journal  | vauthors=Gootjes J, Schmohl F, Waterham HR, Wanders RJ |title=Novel mutations in the PEX12 gene of patients with a peroxisome biogenesis disorder |journal=Eur. J. Hum. Genet. |volume=12 |issue= 2 |pages= 115–20 |year= 2004 |pmid= 14571262 |doi= 10.1038/sj.ejhg.5201090 }}
*{{cite journal | author=Fransen M, Brees C, Ghys K, ''et al.'' |title=Analysis of mammalian peroxin interactions using a non-transcription-based bacterial two-hybrid assay. |journal=Mol. Cell Proteomics |volume=1 |issue= 3 |pages= 243-52 |year= 2002 |pmid= 12096124 |doi=  }}
*{{Cite journal   |vauthors=Gootjes J, Schmohl F, Mooijer PA, etal |title=Identification of the molecular defect in patients with peroxisomal mosaicism using a novel method involving culturing of cells at 40 degrees C: implications for other inborn errors of metabolism |journal=Hum. Mutat. |volume=24 |issue= 2 |pages= 130–9 |year= 2004 |pmid= 15241794 |doi= 10.1002/humu.20062 }}
*{{cite journal  | author=Harper CC, Berg JM, Gould SJ |title=PEX5 binds the PTS1 independently of Hsp70 and the peroxin PEX12. |journal=J. Biol. Chem. |volume=278 |issue= 10 |pages= 7897-901 |year= 2003 |pmid= 12456682 |doi= 10.1074/jbc.M206651200 }}
*{{Cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{Cite journal   |vauthors=Mano S, Nakamori C, Nito K, etal |title=The Arabidopsis pex12 and pex13 mutants are defective in both PTS1- and PTS2-dependent protein transport to peroxisomes |journal=Plant J. |volume=47 |issue= 4 |pages= 604–18 |year= 2007 |pmid= 16813573 |doi= 10.1111/j.1365-313X.2006.02809.x }}
*{{cite journal  | author=Gootjes J, Schmohl F, Waterham HR, Wanders RJ |title=Novel mutations in the PEX12 gene of patients with a peroxisome biogenesis disorder. |journal=Eur. J. Hum. Genet. |volume=12 |issue= 2 |pages= 115-20 |year= 2004 |pmid= 14571262 |doi= 10.1038/sj.ejhg.5201090 }}
*{{Cite journal   |vauthors=Zeharia A, Ebberink MS, Wanders RJ, etal |title=A novel PEX12 mutation identified as the cause of a peroxisomal biogenesis disorder with mild clinical phenotype, mild biochemical abnormalities in fibroblasts and a mosaic catalase immunofluorescence pattern, even at 40 degrees C |journal=J. Hum. Genet. |volume=52 |issue= 7 |pages= 599–606 |year= 2007 |pmid= 17534573 |doi= 10.1007/s10038-007-0157-y }}
*{{cite journal | author=Gootjes J, Schmohl F, Mooijer PA, ''et al.'' |title=Identification of the molecular defect in patients with peroxisomal mosaicism using a novel method involving culturing of cells at 40 degrees C: implications for other inborn errors of metabolism. |journal=Hum. Mutat. |volume=24 |issue= 2 |pages= 130-9 |year= 2004 |pmid= 15241794 |doi= 10.1002/humu.20062 }}
{{Refend}}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
 
*{{cite journal | author=Mano S, Nakamori C, Nito K, ''et al.'' |title=The Arabidopsis pex12 and pex13 mutants are defective in both PTS1- and PTS2-dependent protein transport to peroxisomes. |journal=Plant J. |volume=47 |issue= 4 |pages= 604-18 |year= 2007 |pmid= 16813573 |doi= 10.1111/j.1365-313X.2006.02809.x }}
==External links==
*{{cite journal | author=Zeharia A, Ebberink MS, Wanders RJ, ''et al.'' |title=A novel PEX12 mutation identified as the cause of a peroxisomal biogenesis disorder with mild clinical phenotype, mild biochemical abnormalities in fibroblasts and a mosaic catalase immunofluorescence pattern, even at 40 degrees C. |journal=J. Hum. Genet. |volume=52 |issue= 7 |pages= 599-606 |year= 2007 |pmid= 17534573 |doi= 10.1007/s10038-007-0157-y }}
* [https://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=gene&part=pbd  GeneReviews/NCBI/NIH/UW entry on Peroxisome Biogenesis Disorders, Zellweger Syndrome Spectrum]
}}
* [https://www.ncbi.nlm.nih.gov/omim/170993,202370,214100,266510,600279,600414,601498,601758,601789,601791,602136,602859,603164,603360,608666,170993,202370,214100,266510,600279,600414,601498,601758,601789,601791,602136,602859,603164,603360,608666 OMIM entries on Peroxisome Biogenesis Disorders, Zellweger Syndrome Spectrum]
{{refend}}
 


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Latest revision as of 17:58, 7 September 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Peroxisome assembly protein 12 is a protein that in humans is encoded by the PEX12 gene.[1][2]

Function

PEX12 is needed for protein import into peroxisomes.[3] This gene belongs to the peroxin-12 family. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes.

Clinical significance

The peroxisome biogenesis disorders (PBDs; MIM 601539) are a group of genetically heterogeneous diseases that are usually lethal in early infancy. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. This cellular phenotype is shared by yeast 'pex' mutants, and human orthologs of yeast PEX genes defective in some PBD complementation groups (CGs).[2]

Interactions

PEX12 has been shown to interact with PEX10,[4][5] PEX5[4][5] and PEX19.[6][7]

References

  1. ↑ Chang CC, Lee WH, Moser H, Valle D, Gould SJ (April 1997). "Isolation of the human PEX12 gene, mutated in group 3 of the peroxisome biogenesis disorders". Nat Genet. 15 (4): 385–8. doi:10.1038/ng0497-385. PMID 9090384.
  2. ↑ 2.0 2.1 "Entrez Gene: PEX12 peroxisomal biogenesis factor 12".
  3. ↑ Okumoto K, Shimozawa N, Kawai A, Tamura S, Tsukamoto T, Osumi T, Moser H, Wanders RJ, Suzuki Y, Kondo N, Fujiki Y (July 1998). "PEX12, the pathogenic gene of group III Zellweger syndrome: cDNA cloning by functional complementation on a CHO cell mutant, patient analysis, and characterization of PEX12p". Mol. Cell. Biol. 18 (7): 4324–36. PMC 109016. PMID 9632816.
  4. ↑ 4.0 4.1 Chang CC, Warren DS, Sacksteder KA, Gould SJ (November 1999). "PEX12 interacts with PEX5 and PEX10 and acts downstream of receptor docking in peroxisomal matrix protein import". J. Cell Biol. 147 (4): 761–74. doi:10.1083/jcb.147.4.761. PMC 2156163. PMID 10562279.
  5. ↑ 5.0 5.1 Okumoto K, Abe I, Fujiki Y (August 2000). "Molecular anatomy of the peroxin Pex12p: ring finger domain is essential for Pex12p function and interacts with the peroxisome-targeting signal type 1-receptor Pex5p and a ring peroxin, Pex10p". J. Biol. Chem. 275 (33): 25700–10. doi:10.1074/jbc.M003303200. PMID 10837480.
  6. ↑ Sacksteder KA, Jones JM, South ST, Li X, Liu Y, Gould SJ (March 2000). "PEX19 binds multiple peroxisomal membrane proteins, is predominantly cytoplasmic, and is required for peroxisome membrane synthesis". J. Cell Biol. 148 (5): 931–44. doi:10.1083/jcb.148.5.931. PMC 2174547. PMID 10704444.
  7. ↑ Fransen M, Wylin T, Brees C, Mannaerts GP, Van Veldhoven PP (July 2001). "Human pex19p binds peroxisomal integral membrane proteins at regions distinct from their sorting sequences". Mol. Cell. Biol. 21 (13): 4413–24. doi:10.1128/MCB.21.13.4413-4424.2001. PMC 87101. PMID 11390669.

Further reading

External links


Retrieved from "https://www.wikidoc.org/index.php?title=PEX12&oldid=1418001"