NAP1L1: Difference between revisions

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{{Infobox_gene}}
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'''Nucleosome assembly protein 1-like 1''' is a [[protein]] that in humans is encoded by the ''NAP1L1'' [[gene]].<ref name="pmid8297347">{{cite journal | vauthors = Simon HU, Mills GB, Kozlowski M, Hogg D, Branch D, Ishimi Y, Siminovitch KA | title = Molecular characterization of hNRP, a cDNA encoding a human nucleosome-assembly-protein-I-related gene product involved in the induction of cell proliferation | journal = Biochem J | volume = 297 | issue =  2| pages = 389–97 |date=Mar 1994 | pmid = 8297347 | pmc = 1137842 | doi =  }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: NAP1L1 nucleosome assembly protein 1-like 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4673| accessdate = }}</ref>
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{{GNF_Protein_box
| image = 
| image_source = 
| PDB =
| Name = Nucleosome assembly protein 1-like 1
| HGNCid = 7637
| Symbol = NAP1L1
| AltSymbols =; NAP1; FLJ16112; MGC23410; MGC8688; NAP1L; NRP
| OMIM = 164060
| ECnumber = 
| Homologene = 4355
| MGIid = 1855693
| GeneAtlas_image1 = PBB_GE_NAP1L1_208754_s_at_tn.png
| GeneAtlas_image2 = PBB_GE_NAP1L1_204528_s_at_tn.png
| GeneAtlas_image3 = PBB_GE_NAP1L1_208752_x_at_tn.png
| Function = {{GNF_GO|id=GO:0005515 |text = protein binding}}
| Component = {{GNF_GO|id=GO:0005634 |text = nucleus}} {{GNF_GO|id=GO:0005678 |text = chromatin assembly complex}}
| Process = {{GNF_GO|id=GO:0006260 |text = DNA replication}} {{GNF_GO|id=GO:0006334 |text = nucleosome assembly}} {{GNF_GO|id=GO:0008284 |text = positive regulation of cell proliferation}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 4673
    | Hs_Ensembl = ENSG00000187109
    | Hs_RefseqProtein = NP_004528
    | Hs_RefseqmRNA = NM_004537
    | Hs_GenLoc_db =   
    | Hs_GenLoc_chr = 12
    | Hs_GenLoc_start = 74726227
    | Hs_GenLoc_end = 74764717
    | Hs_Uniprot = P55209
    | Mm_EntrezGene = 53605
    | Mm_Ensembl = ENSMUSG00000058799
    | Mm_RefseqmRNA = NM_015781
    | Mm_RefseqProtein = NP_056596
    | Mm_GenLoc_db =   
    | Mm_GenLoc_chr = 10
    | Mm_GenLoc_start = 110877336
    | Mm_GenLoc_end = 110899309
    | Mm_Uniprot = Q3TF41
  }}
}}
'''Nucleosome assembly protein 1-like 1''', also known as '''NAP1L1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: NAP1L1 nucleosome assembly protein 1-like 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4673| accessdate = }}</ref>


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{{PBB_Summary
{{PBB_Summary
| section_title =  
| section_title =
| summary_text = This gene encodes a member of the nucleosome assembly protein (NAP) family. This protein participates in DNA replication and may play a role in modulating chromatin formation and contribute to the regulation of cell proliferation. Alternative splicing of this gene results in several transcript variants; however, not all have been fully described.<ref name="entrez">{{cite web | title = Entrez Gene: NAP1L1 nucleosome assembly protein 1-like 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4673| accessdate = }}</ref>
| summary_text = This gene encodes a member of the [[nucleosome]] assembly protein (NAP) family. This protein participates in [[DNA replication]] and may play a role in modulating [[chromatin]] formation and contribute to the regulation of [[cell proliferation]]. [[Alternative splicing]] of this gene results in several transcript variants; however, not all have been fully described.<ref name="entrez"/>
}}
}}


==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading
| citations =  
| citations =
*{{cite journal | author=Kato S, Sekine S, Oh SW, ''et al.'' |title=Construction of a human full-length cDNA bank. |journal=Gene |volume=150 |issue= 2 |pages= 243-50 |year= 1995 |pmid= 7821789 |doi= }}
*{{cite journal   |vauthors=Kato S, Sekine S, Oh SW, etal |title=Construction of a human full-length cDNA bank. |journal=Gene |volume=150 |issue= 2 |pages= 243–50 |year= 1995 |pmid= 7821789 |doi=10.1016/0378-1119(94)90433-2 }}
*{{cite journal  | author=Simon HU, Mills GB, Kozlowski M, ''et al.'' |title=Molecular characterization of hNRP, a cDNA encoding a human nucleosome-assembly-protein-I-related gene product involved in the induction of cell proliferation. |journal=Biochem. J. |volume=297 ( Pt 2) |issue=  |pages= 389-97 |year= 1994 |pmid= 8297347 |doi= }}
*{{cite journal   |vauthors=Asahara H, Tartare-Deckert S, Nakagawa T, etal |title=Dual roles of p300 in chromatin assembly and transcriptional activation in cooperation with nucleosome assembly protein 1 in vitro. |journal=Mol. Cell. Biol. |volume=22 |issue= 9 |pages= 2974–83 |year= 2002 |pmid= 11940655 |doi=10.1128/MCB.22.9.2974-2983.2002  | pmc=133748 }}
*{{cite journal | author=Asahara H, Tartare-Deckert S, Nakagawa T, ''et al.'' |title=Dual roles of p300 in chromatin assembly and transcriptional activation in cooperation with nucleosome assembly protein 1 in vitro. |journal=Mol. Cell. Biol. |volume=22 |issue= 9 |pages= 2974-83 |year= 2002 |pmid= 11940655 |doi=  }}
*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal   |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal   |vauthors=Bouwmeester T, Bauch A, Ruffner H, etal |title=A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway. |journal=Nat. Cell Biol. |volume=6 |issue= 2 |pages= 97–105 |year= 2004 |pmid= 14743216 |doi= 10.1038/ncb1086 }}
*{{cite journal | author=Bouwmeester T, Bauch A, Ruffner H, ''et al.'' |title=A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway. |journal=Nat. Cell Biol. |volume=6 |issue= 2 |pages= 97-105 |year= 2004 |pmid= 14743216 |doi= 10.1038/ncb1086 }}
*{{cite journal  | vauthors=Rehtanz M, Schmidt HM, Warthorst U, Steger G |title=Direct interaction between nucleosome assembly protein 1 and the papillomavirus E2 proteins involved in activation of transcription. |journal=Mol. Cell. Biol. |volume=24 |issue= 5 |pages= 2153–68 |year= 2004 |pmid= 14966293 |doi=10.1128/MCB.24.5.2153-2168.2004  | pmc=350572 }}
*{{cite journal  | author=Rehtanz M, Schmidt HM, Warthorst U, Steger G |title=Direct interaction between nucleosome assembly protein 1 and the papillomavirus E2 proteins involved in activation of transcription. |journal=Mol. Cell. Biol. |volume=24 |issue= 5 |pages= 2153-68 |year= 2004 |pmid= 14966293 |doi=  }}
*{{cite journal   |vauthors=Kho Y, Kim SC, Jiang C, etal |title=A tagging-via-substrate technology for detection and proteomics of farnesylated proteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 34 |pages= 12479–84 |year= 2004 |pmid= 15308774 |doi= 10.1073/pnas.0403413101 | pmc=515085 }}
*{{cite journal | author=Kho Y, Kim SC, Jiang C, ''et al.'' |title=A tagging-via-substrate technology for detection and proteomics of farnesylated proteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 34 |pages= 12479-84 |year= 2004 |pmid= 15308774 |doi= 10.1073/pnas.0403413101 }}
*{{cite journal   |vauthors=Ballif BA, Villén J, Beausoleil SA, etal |title=Phosphoproteomic analysis of the developing mouse brain. |journal=Mol. Cell. Proteomics |volume=3 |issue= 11 |pages= 1093–101 |year= 2005 |pmid= 15345747 |doi= 10.1074/mcp.M400085-MCP200 }}
*{{cite journal | author=Ballif BA, Villén J, Beausoleil SA, ''et al.'' |title=Phosphoproteomic analysis of the developing mouse brain. |journal=Mol. Cell Proteomics |volume=3 |issue= 11 |pages= 1093-101 |year= 2005 |pmid= 15345747 |doi= 10.1074/mcp.M400085-MCP200 }}
*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal   |vauthors=Okuwaki M, Kato K, Shimahara H, etal |title=Assembly and disassembly of nucleosome core particles containing histone variants by human nucleosome assembly protein I. |journal=Mol. Cell. Biol. |volume=25 |issue= 23 |pages= 10639–51 |year= 2005 |pmid= 16287874 |doi= 10.1128/MCB.25.23.10639-10651.2005 | pmc=1291234 }}
*{{cite journal | author=Okuwaki M, Kato K, Shimahara H, ''et al.'' |title=Assembly and disassembly of nucleosome core particles containing histone variants by human nucleosome assembly protein I. |journal=Mol. Cell. Biol. |volume=25 |issue= 23 |pages= 10639-51 |year= 2005 |pmid= 16287874 |doi= 10.1128/MCB.25.23.10639-10651.2005 }}
*{{cite journal   |vauthors=Nousiainen M, Silljé HH, Sauer G, etal |title=Phosphoproteome analysis of the human mitotic spindle. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=103 |issue= 14 |pages= 5391–6 |year= 2006 |pmid= 16565220 |doi= 10.1073/pnas.0507066103 | pmc=1459365 }}
*{{cite journal | author=Nousiainen M, Silljé HH, Sauer G, ''et al.'' |title=Phosphoproteome analysis of the human mitotic spindle. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=103 |issue= 14 |pages= 5391-6 |year= 2006 |pmid= 16565220 |doi= 10.1073/pnas.0507066103 }}
*{{cite journal   |vauthors=Beausoleil SA, Villén J, Gerber SA, etal |title=A probability-based approach for high-throughput protein phosphorylation analysis and site localization. |journal=Nat. Biotechnol. |volume=24 |issue= 10 |pages= 1285–92 |year= 2006 |pmid= 16964243 |doi= 10.1038/nbt1240 }}
*{{cite journal | author=Beausoleil SA, Villén J, Gerber SA, ''et al.'' |title=A probability-based approach for high-throughput protein phosphorylation analysis and site localization. |journal=Nat. Biotechnol. |volume=24 |issue= 10 |pages= 1285-92 |year= 2006 |pmid= 16964243 |doi= 10.1038/nbt1240 }}
*{{cite journal   |vauthors=Chi A, Valencia JC, Hu ZZ, etal |title=Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes. |journal=J. Proteome Res. |volume=5 |issue= 11 |pages= 3135–44 |year= 2007 |pmid= 17081065 |doi= 10.1021/pr060363j }}
*{{cite journal | author=Chi A, Valencia JC, Hu ZZ, ''et al.'' |title=Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes. |journal=J. Proteome Res. |volume=5 |issue= 11 |pages= 3135-44 |year= 2007 |pmid= 17081065 |doi= 10.1021/pr060363j }}
*{{cite journal   |vauthors=Olsen JV, Blagoev B, Gnad F, etal |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635–48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026 }}
*{{cite journal | author=Olsen JV, Blagoev B, Gnad F, ''et al.'' |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635-48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026 }}
*{{cite journal  | vauthors=Eckey M, Hong W, Papaioannou M, Baniahmad A |title=The nucleosome assembly activity of NAP1 is enhanced by Alien. |journal=Mol. Cell. Biol. |volume=27 |issue= 10 |pages= 3557–68 |year= 2007 |pmid= 17339334 |doi= 10.1128/MCB.01106-06 | pmc=1899999 }}
*{{cite journal  | author=Eckey M, Hong W, Papaioannou M, Baniahmad A |title=The nucleosome assembly activity of NAP1 is enhanced by Alien. |journal=Mol. Cell. Biol. |volume=27 |issue= 10 |pages= 3557-68 |year= 2007 |pmid= 17339334 |doi= 10.1128/MCB.01106-06 }}
}}
}}
{{refend}}
{{refend}}


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[[Category:Human proteins]]
 
 
{{gene-12-stub}}

Latest revision as of 12:26, 5 September 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Nucleosome assembly protein 1-like 1 is a protein that in humans is encoded by the NAP1L1 gene.[1][2]

This gene encodes a member of the nucleosome assembly protein (NAP) family. This protein participates in DNA replication and may play a role in modulating chromatin formation and contribute to the regulation of cell proliferation. Alternative splicing of this gene results in several transcript variants; however, not all have been fully described.[2]

References

  1. ↑ Simon HU, Mills GB, Kozlowski M, Hogg D, Branch D, Ishimi Y, Siminovitch KA (Mar 1994). "Molecular characterization of hNRP, a cDNA encoding a human nucleosome-assembly-protein-I-related gene product involved in the induction of cell proliferation". Biochem J. 297 (2): 389–97. PMC 1137842. PMID 8297347.
  2. ↑ 2.0 2.1 "Entrez Gene: NAP1L1 nucleosome assembly protein 1-like 1".

Further reading


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