Alizapride: Difference between revisions
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'''Alizapride''' is a [[dopamine antagonist]] with [[prokinetic]] and [[antiemetic]] effects used in the treatment of [[nausea]] and [[vomiting]], including [[postoperative nausea and vomiting]]. It is structurally related to [[metoclopramide]].<ref>{{cite journal |author=Bleiberg H, Gerard B, Dalesio O, Crespeigne N, Rozencweig M |title=Activity of a new antiemetic agent: alizapride. A randomized double-blind crossover controlled trial |journal=Cancer Chemother Pharmacol |volume=22 |issue=4 |pages=316–20 |year=1988 |pmid=3048762 |doi=}}</ref> | '''Alizapride''' is a [[dopamine antagonist]] with [[prokinetic]] and [[antiemetic]] effects used in the treatment of [[nausea]] and [[vomiting]], including [[postoperative nausea and vomiting]]. It is structurally related to [[metoclopramide]].<ref>{{cite journal |author=Bleiberg H, Gerard B, Dalesio O, Crespeigne N, Rozencweig M |title=Activity of a new antiemetic agent: alizapride. A randomized double-blind crossover controlled trial |journal=Cancer Chemother Pharmacol |volume=22 |issue=4 |pages=316–20 |year=1988 |pmid=3048762 |doi=}}</ref> |
Revision as of 20:52, 8 August 2012
File:Alizapride.svg | |
Clinical data | |
---|---|
Routes of administration | Oral, intramuscular, intravenous |
ATC code | |
Pharmacokinetic data | |
Elimination half-life | 3 hours |
Excretion | Renal |
Identifiers | |
| |
CAS Number | |
PubChem CID | |
E number | {{#property:P628}} |
ECHA InfoCard | {{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value). |
Chemical and physical data | |
Formula | C16H21N5O2 |
Molar mass | 315.37 g/mol |
Alizapride is a dopamine antagonist with prokinetic and antiemetic effects used in the treatment of nausea and vomiting, including postoperative nausea and vomiting. It is structurally related to metoclopramide.[1]
Alizapride is marketed under various trade names including Plitican, Superan and Vergentan.[2]
References
- ↑ Bleiberg H, Gerard B, Dalesio O, Crespeigne N, Rozencweig M (1988). "Activity of a new antiemetic agent: alizapride. A randomized double-blind crossover controlled trial". Cancer Chemother Pharmacol. 22 (4): 316–20. PMID 3048762.
- ↑ Template:Fr icon "Alizapride Chlorhydrate". BIAM. June 2 1997. Retrieved 2007-08-14. Check date values in:
|date=
(help)
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- Pharmacology
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- Dopamine antagonists
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