Alizapride: Difference between revisions

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'''Alizapride''' is a [[dopamine antagonist]] with [[prokinetic]] and [[antiemetic]] effects used in the treatment of [[nausea]] and [[vomiting]], including [[postoperative nausea and vomiting]]. It is  structurally related to [[metoclopramide]].<ref>{{cite journal |author=Bleiberg H, Gerard B, Dalesio O, Crespeigne N, Rozencweig M |title=Activity of a new antiemetic agent: alizapride. A randomized double-blind crossover controlled trial |journal=Cancer Chemother Pharmacol |volume=22 |issue=4 |pages=316–20 |year=1988 |pmid=3048762 |doi=}}</ref>
'''Alizapride''' is a [[dopamine antagonist]] with [[prokinetic]] and [[antiemetic]] effects used in the treatment of [[nausea]] and [[vomiting]], including [[postoperative nausea and vomiting]]. It is  structurally related to [[metoclopramide]].<ref>{{cite journal |author=Bleiberg H, Gerard B, Dalesio O, Crespeigne N, Rozencweig M |title=Activity of a new antiemetic agent: alizapride. A randomized double-blind crossover controlled trial |journal=Cancer Chemother Pharmacol |volume=22 |issue=4 |pages=316–20 |year=1988 |pmid=3048762 |doi=}}</ref>

Revision as of 20:52, 8 August 2012

Alizapride
File:Alizapride.svg
Clinical data
Routes of
administration
Oral, intramuscular, intravenous
ATC code
Pharmacokinetic data
Elimination half-life3 hours
ExcretionRenal
Identifiers
CAS Number
PubChem CID
E number{{#property:P628}}
ECHA InfoCard{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
FormulaC16H21N5O2
Molar mass315.37 g/mol


Alizapride is a dopamine antagonist with prokinetic and antiemetic effects used in the treatment of nausea and vomiting, including postoperative nausea and vomiting. It is structurally related to metoclopramide.[1]

Alizapride is marketed under various trade names including Plitican, Superan and Vergentan.[2]

References

  1. Bleiberg H, Gerard B, Dalesio O, Crespeigne N, Rozencweig M (1988). "Activity of a new antiemetic agent: alizapride. A randomized double-blind crossover controlled trial". Cancer Chemother Pharmacol. 22 (4): 316–20. PMID 3048762.
  2. Template:Fr icon "Alizapride Chlorhydrate". BIAM. June 2 1997. Retrieved 2007-08-14. Check date values in: |date= (help)


Template:Drugs for functional gastrointestinal disorders