Adrenoleukodystrophy (patient information): Difference between revisions
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==What causes Adrenoleukodystrophy?== | ==What causes Adrenoleukodystrophy?== | ||
[[Adrenoleukodystrophy]] is passed down from parents to their children as an [[X-linked]] [[genetic trait]]. It therefore affects mostly [[males]], although some [[women]] who are [[Genetic carrier|carriers]] can have milder forms of the [[disease]]. It affects approximately 1 in 20,000 people from all races. | |||
The [[condition]] results in the buildup of very-long-chain [[fatty acids]] in the [[nervous system]], [[adrenal gland]], and [[testes]], which disrupts normal activity. There are three major categories of [[disease]]: | |||
*Childhood cerebral form -- appears in mid-childhood (at ages 4 - 8) | |||
*Adrenomyelopathy -- occurs in men in their 20s or later in life | |||
*Impaired [[adrenal gland]] function (called [[Addison disease]] or Addison-like [[phenotype]]) -- [[adrenal gland]] does not produce enough [[steroid hormones]] | |||
==Who is at risk for Adrenoleukodystrophy?== | ==Who is at risk for Adrenoleukodystrophy?== |
Revision as of 20:55, 26 March 2010
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What is Adrenoleukodystrophy?
Adrenoleukodystrophy describes several closely related inherited disorders that disrupt the breakdown (metabolism) of certain fats (very-long-chain fatty acids).
What are the symptoms of Adrenoleukodystrophy?
What causes Adrenoleukodystrophy?
Adrenoleukodystrophy is passed down from parents to their children as an X-linked genetic trait. It therefore affects mostly males, although some women who are carriers can have milder forms of the disease. It affects approximately 1 in 20,000 people from all races.
The condition results in the buildup of very-long-chain fatty acids in the nervous system, adrenal gland, and testes, which disrupts normal activity. There are three major categories of disease:
- Childhood cerebral form -- appears in mid-childhood (at ages 4 - 8)
- Adrenomyelopathy -- occurs in men in their 20s or later in life
- Impaired adrenal gland function (called Addison disease or Addison-like phenotype) -- adrenal gland does not produce enough steroid hormones
Who is at risk for Adrenoleukodystrophy?
How do I know I have Adrenoleukodystrophy?
When to seek urgent medical care
Treatment options
Where to find medical care for Adrenoleukodystrophy
Directions to Hospitals Treating Adrenoleukodystrophy