ACTR1B: Difference between revisions
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(New page: {{PBB|geneid=10120}} '''ARP1 actin-related protein 1 homolog B, centractin beta (yeast)''', also known as '''ACTR1B''', is a human gene.<ref name="entrez">{{cite web | title = Entrez G...) |
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| image = | |||
| image_source = | |||
| PDB = | |||
| Name = ARP1 actin-related protein 1 homolog B, centractin beta (yeast) | |||
| HGNCid = 168 | |||
| Symbol = ACTR1B | |||
| AltSymbols =; ARP1 | |||
| OMIM = 605144 | |||
| ECnumber = | |||
| Homologene = 21173 | |||
| MGIid = 1917446 | |||
| GeneAtlas_image1 = PBB_GE_ACTR1A_200720_s_at_tn.png | |||
| GeneAtlas_image2 = PBB_GE_ACTR1A_200721_s_at_tn.png | |||
| GeneAtlas_image3 = PBB_GE_ACTR1A_gnf1h07451_s_at_tn.png | |||
| Function = {{GNF_GO|id=GO:0000166 |text = nucleotide binding}} {{GNF_GO|id=GO:0005198 |text = structural molecule activity}} {{GNF_GO|id=GO:0005515 |text = protein binding}} {{GNF_GO|id=GO:0005524 |text = ATP binding}} | |||
| Component = {{GNF_GO|id=GO:0005737 |text = cytoplasm}} {{GNF_GO|id=GO:0005856 |text = cytoskeleton}} {{GNF_GO|id=GO:0005869 |text = dynactin complex}} | |||
| Process = {{GNF_GO|id=GO:0016192 |text = vesicle-mediated transport}} | |||
| Orthologs = {{GNF_Ortholog_box | |||
| Hs_EntrezGene = 10120 | |||
| Hs_Ensembl = ENSG00000115073 | |||
| Hs_RefseqProtein = NP_005735 | |||
| Hs_RefseqmRNA = NM_005736 | |||
| Hs_GenLoc_db = | |||
| Hs_GenLoc_chr = 2 | |||
| Hs_GenLoc_start = 97638863 | |||
| Hs_GenLoc_end = 97646815 | |||
| Hs_Uniprot = P42025 | |||
| Mm_EntrezGene = 226977 | |||
| Mm_Ensembl = ENSMUSG00000037351 | |||
| Mm_RefseqmRNA = | |||
| Mm_RefseqProtein = | |||
| Mm_GenLoc_db = | |||
| Mm_GenLoc_chr = 1 | |||
| Mm_GenLoc_start = 36756047 | |||
| Mm_GenLoc_end = 36766769 | |||
| Mm_Uniprot = Q8R5C5 | |||
}} | |||
}} | |||
'''ARP1 actin-related protein 1 homolog B, centractin beta (yeast)''', also known as '''ACTR1B''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: ACTR1B ARP1 actin-related protein 1 homolog B, centractin beta (yeast)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10120| accessdate = }}</ref> | '''ARP1 actin-related protein 1 homolog B, centractin beta (yeast)''', also known as '''ACTR1B''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: ACTR1B ARP1 actin-related protein 1 homolog B, centractin beta (yeast)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10120| accessdate = }}</ref> | ||
Revision as of 21:09, 3 March 2009
| ARP1 actin-related protein 1 homolog B, centractin beta (yeast) | |||||||||||
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| Identifiers | |||||||||||
| Symbols | ACTR1B ; ARP1 | ||||||||||
| External IDs | Template:OMIM5 Template:MGI HomoloGene: 21173 | ||||||||||
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| RNA expression pattern | |||||||||||
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| More reference expression data | |||||||||||
| Orthologs | |||||||||||
| Template:GNF Ortholog box | |||||||||||
| Species | Human | Mouse | |||||||||
| Entrez | n/a | n/a | |||||||||
| Ensembl | n/a | n/a | |||||||||
| UniProt | n/a | n/a | |||||||||
| RefSeq (mRNA) | n/a | n/a | |||||||||
| RefSeq (protein) | n/a | n/a | |||||||||
| Location (UCSC) | n/a | n/a | |||||||||
| PubMed search | n/a | n/a | |||||||||
ARP1 actin-related protein 1 homolog B, centractin beta (yeast), also known as ACTR1B, is a human gene.[1]
This gene encodes a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like ACTR1A, is an actin-related protein. These two proteins are of equal length and share 90% amino acid identity. They are present in a constant ratio of approximately 1:15 in the dynactin complex.[1]