Acute disseminated encephalomyelitis epidemiology and demographics: Difference between revisions

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===Incidence===
===Incidence===


*The [https://www.wikidoc.org/index.php/Tumor tumor] [https://www.wikidoc.org/index.php/Incidence incidence] has been reported 0.049 cases per 100,000 child aged 5 to 9.
*The [[Incidence (epidemiology)|Incidence]] of [[Acute disseminated encephalomyelitis causes|Acute disseminated encephalomyelitis]] is about 1 in 125,000-250,000 people each year, in children younger than 10 years, despite the fact that it is a rare disorder.
*The [[Incidence (epidemiology)|Incidence]] of [[Acute disseminated encephalomyelitis]] is about 1 in 125,000-250,000 people each year, in children younger than 10 years, despite the fact that it is a rare disorder.
*Each year, regional medical centers in the United States, the United Kingdom, and Australia see three to six instances.


===Prevalence===
===Prevalence===
Line 26: Line 26:
===Age===
===Age===


*The [https://www.wikidoc.org/index.php/Median median] age at the time of [https://www.wikidoc.org/index.php/Diagnosis diagnosis] is 18 months.<ref name="pmid9544909">{{cite journal| author=Abramson DH, Frank CM, Susman M, Whalen MP, Dunkel IJ, Boyd NW| title=Presenting signs of retinoblastoma. | journal=J Pediatr | year= 1998 | volume= 132 | issue= 3 Pt 1 | pages= 505-8 | pmid=9544909 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9544909  }}</ref>
*In youngsters, the usual [[age]] of onset is 3 to 7 years.
*The average age at [https://www.wikidoc.org/index.php/Diagnosis diagnosis] of retinoblastoma for children with unilateral [https://www.wikidoc.org/index.php/Disease disease] and [https://www.wikidoc.org/index.php/Bilateral bilateral] [https://www.wikidoc.org/index.php/Disease disease] is 24 months and 12 months respectively.<ref name="pmid18621794">{{cite journal| author=Broaddus E, Topham A, Singh AD| title=Incidence of retinoblastoma in the USA: 1975-2004. | journal=Br J Ophthalmol | year= 2009 | volume= 93 | issue= 1 | pages= 21-3 | pmid=18621794 | doi=10.1136/bjo.2008.138750 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18621794  }}</ref>
*Cases have also been reported in children between the ages of 10 and twenty.
*Cases of newly [https://www.wikidoc.org/index.php/Diagnose diagnosed] retinoblastoma have been reported in children as old as 18 years and even in [https://www.wikidoc.org/index.php/Adult adults].<ref name="pmid4132770">{{cite journal| author=Binder PS| title=Unusual manifestations of retinoblastoma. | journal=Am J Ophthalmol | year= 1974 | volume= 77 | issue= 5 | pages= 674-9 | pmid=4132770 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=4132770  }}</ref><ref name="pmid6830100">{{cite journal| author=Zakka KA, Yee RD, Foos RY| title=Retinoblastoma in a 12-year-old girl. | journal=Ann Ophthalmol | year= 1983 | volume= 15 | issue= 1 | pages= 88-91 | pmid=6830100 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=6830100  }}</ref>
*Adults between the ages of 18 and 82 are also affected.
*In [https://www.wikidoc.org/index.php/Adult adults], retinoblastoma tends to present between 20 to 50 years of age.<ref name="pmid26035399">{{cite journal |vauthors=Kaliki S, Shields CL, Gupta A, Mishra DK, Das C, Say EA, Shields JA |title=NEWLY DIAGNOSED ACTIVE RETINOBLASTOMA IN ADULTS |journal=Retina (Philadelphia, Pa.) |volume=35 |issue=12 |pages=2483–8 |date=December 2015 |pmid=26035399 |doi=10.1097/IAE.0000000000000612 |url=}}</ref>
*Trilateral retinoblastoma is a well-recognized [https://www.wikidoc.org/index.php/Syndrome syndrome] that occurs in 5% to 15% of [https://www.wikidoc.org/index.php/Patient patients] with [https://www.wikidoc.org/index.php/Heritable heritable] retinoblastoma and is defined by the [https://www.wikidoc.org/index.php/Development development] of an [https://www.wikidoc.org/index.php/Cranial intracranial] midline [https://www.wikidoc.org/index.php/Neuroblast neuroblastic] [https://www.wikidoc.org/index.php/Tumor tumor], which typically develops between the ages of 20 and 36 months.


===Gender===
===Gender===


*Retinoblastoma affects [https://www.wikidoc.org/index.php/Male males] and [https://www.wikidoc.org/index.php/Female females] equally.<ref name="pmid9544909" />
*Retinoblastoma affects [https://www.wikidoc.org/index.php/Male males] and [https://www.wikidoc.org/index.php/Female females] equally.<ref name="pmid9544909">{{cite journal| author=Abramson DH, Frank CM, Susman M, Whalen MP, Dunkel IJ, Boyd NW| title=Presenting signs of retinoblastoma. | journal=J Pediatr | year= 1998 | volume= 132 | issue= 3 Pt 1 | pages= 505-8 | pmid=9544909 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9544909  }}</ref>


===Race===
===Race===

Revision as of 21:43, 26 June 2021

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Overview

Epidemiology and Demographics


Incidence

  • The Incidence of Acute disseminated encephalomyelitis is about 1 in 125,000-250,000 people each year, in children younger than 10 years, despite the fact that it is a rare disorder.
  • Each year, regional medical centers in the United States, the United Kingdom, and Australia see three to six instances.

Prevalence

  • There is no data on the prevalence of retinoblastoma.

Case-fatality rate/Mortality rate

Age

  • In youngsters, the usual age of onset is 3 to 7 years.
  • Cases have also been reported in children between the ages of 10 and twenty.
  • Adults between the ages of 18 and 82 are also affected.

Gender

Race

  • There is no racial predilection to the development of retinoblastoma.[4]

Region

  • Epidemiological data indicates that retinoblastoma has a higher incidence in some geographic areas.[5]
  • The table below provides the highest worldwide incidence rate of retinoblastoma in children aged 0 - 4:

References

  1. ↑ Dimaras, Helen; Kimani, Kahaki; Dimba, Elizabeth AO; Gronsdahl, Peggy; White, Abby; Chan, Helen SL; Gallie, Brenda L (2012). "Retinoblastoma". The Lancet. 379 (9824): 1436–1446. doi:10.1016/S0140-6736(11)61137-9. ISSN 0140-6736.
  2. ↑ Kim, J W; Kathpalia, V; Dunkel, I J; Wong, R K; Riedel, E; Abramson, D H (2008). "Orbital recurrence of retinoblastoma following enucleation". British Journal of Ophthalmology. 93 (4): 463–467. doi:10.1136/bjo.2008.138453. ISSN 0007-1161.
  3. ↑ Chévez-Barrios, Patricia; Eagle, Ralph C.; Marback, Eduardo F. (2015). "Histopathologic Features and Prognostic Factors": 167–183. doi:10.1007/978-3-662-43451-2_16.
  4. ↑ 4.0 4.1 Abramson DH, Frank CM, Susman M, Whalen MP, Dunkel IJ, Boyd NW (1998). "Presenting signs of retinoblastoma". J Pediatr. 132 (3 Pt 1): 505–8. PMID 9544909.
  5. ↑ Singh, Arun (2007). Clinical ophthalmic oncology. Edinburgh: Elsevier Saunders. ISBN 978-1-4160-3167-3.
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