Sandbox:Hannan: Difference between revisions
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Hannan Javed (talk | contribs) No edit summary |
Hannan Javed (talk | contribs) No edit summary |
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(CML), BCR-ABL1+ | (CML), BCR-ABL1+ | ||
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| | * <small>50% of patients are asymptomatic</small> | ||
* <small>Clinical features are generally nonspecific</small> | |||
* <small>left upper quadrant pain</small> | |||
* <small>early satiety</small> | |||
* <small>fatigue</small> | |||
* <small>night sweats</small> | |||
* <small>symptoms of anemia</small> | |||
* <small>bleeding</small> | |||
* <small>symptoms of hyperviscosity such as priapism</small> | |||
|splenomegaly46–76% | |||
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Revision as of 15:04, 15 January 2019
Myeloproliferative neoplasms (MPN) | Clinical manifestations | Diagnosis | Other features | ||||
---|---|---|---|---|---|---|---|
Symptoms | Physical examination | Lab findings | Bone marrow biopsy | Gold standard | Other investigations | ||
Chronic myeloid leukemia
(CML), BCR-ABL1+ |
|
splenomegaly46–76% | |||||
Chronic neutrophilic leukemia (CNL) | |||||||
Polycythemia vera (PV) | |||||||
Primary myelofibrosis (PMF)
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Essential thrombocythemia (ET) | |||||||
Chronic eosinophilic leukemia, not otherwise specified (NOS) | |||||||
MPN, unclassifiable | |||||||
Mastocytosis |
Other myeloid neoplasm and acute leukemia | Clinical manifestations | Diagnosis | Other features | ||||
---|---|---|---|---|---|---|---|
Symptoms | Physical examination | Lab findings | Bone marrow biopsy | Gold standard | Other investigations | ||
Myeloid/lymphoid neoplasms with eosinophilia and rearrangement of
PDGFRA, PDGFRB, or FGFR1, or with PCM1-JAK2
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Myelodysplastic/myeloproliferative neoplasms (MDS/MPN)
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Myelodysplastic syndromes (MDS)
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Acute myeloid leukemia (AML) and related neoplasms
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Blastic plasmacytoid dendritic cell neoplasm | |||||||
Acute leukemias of ambiguous lineage
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B-lymphoblastic leukemia/lymphoma
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T-lymphoblastic leukemia/lymphoma
|