Myxedema coma natural history, complications, and prognosis: Difference between revisions
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==Prognosis== | ==Prognosis== | ||
*The mortality rate in myxedema coma is 20% to 25% despite aggressive therapy. | *The mortality rate in myxedema coma is 20% to 25% despite aggressive therapy. | ||
*If myxedema coma is not promptly diagnosed even with immediate intervention, mortality rates are as high as 25%. | |||
*The most common causes of death are respiratory failure, sepsis, and gastrointestinal bleeding. | |||
===Factors suggesting a poor prognosis === | |||
**Older age | |||
**Persistent hypothermia | |||
**Bradycardia | |||
**Lower degree of consciousness by Glasgow Coma Scale | |||
**Multiorgan impairment indicated by high APACHE (Acute Physiology and Chronic Health Evaluation) II score. | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} |
Revision as of 20:59, 8 October 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Aditya Ganti M.B.B.S. [2]
Overview
Natural History
Complications
Prognosis
- The mortality rate in myxedema coma is 20% to 25% despite aggressive therapy.
- If myxedema coma is not promptly diagnosed even with immediate intervention, mortality rates are as high as 25%.
- The most common causes of death are respiratory failure, sepsis, and gastrointestinal bleeding.
Factors suggesting a poor prognosis
- Older age
- Persistent hypothermia
- Bradycardia
- Lower degree of consciousness by Glasgow Coma Scale
- Multiorgan impairment indicated by high APACHE (Acute Physiology and Chronic Health Evaluation) II score.