Acrodermatitis chronica atrophicans natural history, complications and prognosis: Difference between revisions

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{{CMG}}; {{AE}} {{RT}}
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==Overview==


==Natural History==
==Natural History, Complications, and Prognosis==
The course of ACA is long-standing, from a few to several years, and it leads to extensive [[atrophy]] of the skin and, in some patients, to the limitation of upper and lower limb [[joint]] mobility.


==Prognosis==
===Natural History===
The outlook is good if the [[inflammation#Acute inflammation|acute inflammatory]] stage of ACA is treated adequately. The therapeutic outcome is difficult to assess in patients with the chronic atrophic phase, in which many changes are only partially reversible.
*The course of [[acrodermatitis chronica atrophicansis]] is chronic and could lasts for several years. <ref name="pmid30311153">{{cite journal| author=Khalili M, Wong RJ| title=Underserved Does Not Mean Undeserved: Unfurling the HCV Care in the Safety Net. | journal=Dig Dis Sci | year= 2018 | volume= 63 | issue= 12 | pages= 3250-3252 | pmid=30311153 | doi=10.1007/s10620-018-5316-9 | pmc=6436636 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=30311153  }} </ref>
*It usually involves [[Extension (kinesiology)|extensor surfaces]] of the [[Limb (anatomy)|acral regions of limbs]].<ref name="pmid30311153">{{cite journal| author=Khalili M, Wong RJ| title=Underserved Does Not Mean Undeserved: Unfurling the HCV Care in the Safety Net. | journal=Dig Dis Sci | year= 2018 | volume= 63 | issue= 12 | pages= 3250-3252 | pmid=30311153 | doi=10.1007/s10620-018-5316-9 | pmc=6436636 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=30311153  }} </ref>
*[[Skin]] changes first appear as blue and red discoloration with boggy infiltration. These [[skin]] lesions can become [[atrophy|atrophic]] later.
===Complications===
*Common [[Complication (medicine)|complications]] of [[acrodermatitis chronica atrophicansis]] include:<ref name="pmid30311153">{{cite journal| author=Khalili M, Wong RJ| title=Underserved Does Not Mean Undeserved: Unfurling the HCV Care in the Safety Net. | journal=Dig Dis Sci | year= 2018 | volume= 63 | issue= 12 | pages= 3250-3252 | pmid=30311153 | doi=10.1007/s10620-018-5316-9 | pmc=6436636 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=30311153  }} </ref>
**Sclerotic [[skin]] changes
===Prognosis===
*[[Acrodermatitis chronica atrophicansis]] can lead to extensive [[atrophy]] of [[skin]] and, in some [[patients]] it can cause limitation of [[Upper limb|upper]] and [[Leg|lower limb]] [[joint]] mobility.
*The general [[pognosis]] is good with proper and rapid [[treatment]] in [[inflammation#Acute inflammation|acute inflammatory]] stage of [[acrodermatitis chronica atrophicansis]].  
*The [[Therapy|therapeutic]] outcome is difficult to assess in [[patients]] with the chronic [[atrophy|atrophic phase]] because most changes are only partially reversible.


==References==
==References==

Revision as of 12:31, 2 June 2021

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Anahita Deylamsalehi, M.D.[2] Raviteja Guddeti, M.B.B.S. [3]

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  1. 1.0 1.1 1.2 Khalili M, Wong RJ (2018). "Underserved Does Not Mean Undeserved: Unfurling the HCV Care in the Safety Net". Dig Dis Sci. 63 (12): 3250–3252. doi:10.1007/s10620-018-5316-9. PMC 6436636. PMID 30311153.

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