Sandbox:MDS: Difference between revisions

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| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''Chronic myelomonocytic leukemia (CMML)'''|| style="padding: 5px 5px; background: #F5F5F5;" |
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''Chronic myelomonocytic leukemia (CMML)'''|| style="padding: 5px 5px; background: #F5F5F5;" |
:*Less than 20% myeloblasts in the bone marrow and greater than 1*109/L monocytes in peripheral blood.
:*Less than 20% myeloblasts in the bone marrow and greater than 1*109/L monocytes in peripheral blood.
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{| style="border: 0px; font-size: 90%; margin: 3px; width: 1000px"
|valign=top|
|+
! style="background: #4479BA; width: 250px; color: #FFFFFF;"|'''Old system'''
! style="background: #4479BA; width: 600px; color: #FFFFFF;"|'''New system'''
|-
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''[[Refractory anemia]]'''|| style="padding: 5px 5px; background: #F5F5F5;" |
:*Refractory cytopenia with unilineage dysplasia
|-
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''[[Refractory anemia with ringed sideroblasts]]'''|| style="padding: 5px 5px; background: #F5F5F5;"|
:*Refractory anemia with ring sideroblasts
|-
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | || style="padding: 5px 5px; background: #F5F5F5;"|:*Refractory cytopenia with multilineage dysplasia
|-
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''[[Refractory anemia with excess blasts]]'''|| style="padding: 5px 5px; background: #F5F5F5;"|
:*Refractory anemias with excess blasts I and II
|-
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''[[Refractory anemia with excess blasts in transformation]] I–IV '''|| style="padding: 5px 5px; background: #F5F5F5;" |
:*5q - syndrome
|-
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''[[Chronic myelomonocytic leukemia]]'''|| style="padding: 5px 5px; background: #F5F5F5;" |
:*Myelodysplastic-myeloproliferative overlap syndromes
|-
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center |
| style="padding: 5px 5px; background: #F5F5F5;"|
:*Refractory cytopenia of childhood
|-
|style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center |
| style="padding: 5px 5px; background: #F5F5F5;" |
:*Unclassifiable myelodysplastic syndrome


|}
|}

Revision as of 14:35, 8 December 2015

Name Description
Refractory anemia
  • Less than 5% primitive blood cells (myeloblasts) in the bone marrow and pathological abnormalities primarily seen in red cell precursors.
Refractory anemia with ring sideroblasts (RARS)
  • Less than 5% myeloblasts in the bone marrow, but distinguished by the presence of 15% or greater red cell precursors in the marrow being abnormal iron-stuffed cells called ringed sideroblasts.
Refractory anemia with excess blasts (RAEB)
  • 5-20% myeloblasts in the marrow.
Refractory anemia with excess blasts in transformation (RAEB-T)
  • 21-30% myeloblasts in the marrow (>30% blasts is defined as acute myeloid leukemia).
Chronic myelomonocytic leukemia (CMML)
  • Less than 20% myeloblasts in the bone marrow and greater than 1*109/L monocytes in peripheral blood.



Old system New system
Refractory anemia
  • Refractory cytopenia with unilineage dysplasia
Refractory anemia with ringed sideroblasts
  • Refractory anemia with ring sideroblasts
:*Refractory cytopenia with multilineage dysplasia
Refractory anemia with excess blasts
  • Refractory anemias with excess blasts I and II


Refractory anemia with excess blasts in transformation I–IV
  • 5q - syndrome
Chronic myelomonocytic leukemia
  • Myelodysplastic-myeloproliferative overlap syndromes
  • Refractory cytopenia of childhood
  • Unclassifiable myelodysplastic syndrome