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==Overview==
==Overview==
Lipoma may be caused by either gene, or injury.


==Causes==
==Causes==

Revision as of 12:46, 21 August 2015

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Lipoma may be caused by either gene, or injury.

Causes

  • Heredity
The tendency to develop a lipoma is not necessarily hereditary although hereditary conditions, such as familial multiple lipomatosis, may include lipoma development.[1][2] Genetic studies in mice have shown a correlation between the HMG I-C gene (previously identified as a gene related to obesity) and lipoma development.
  • Trauma
Cases have been reported where minor injuries are alleged to have triggered the growth of a lipoma, called "post-traumatic lipomas"[3]. However, the link between trauma and the development of lipomas is controversial.[4]

References

  1. Leffell DJ, Braverman IM (August 1986). "Familial multiple lipomatosis. Report of a case and a review of the literature". J. Am. Acad. Dermatol. 15 (2 Pt 1): 275–9. doi:10.1016/S0190-9622(86)70166-7. PMID 3745530.
  2. Toy BR (October 2003). "Familial multiple lipomatosis". Dermatol. Online J. 9 (4): 9. PMID 14594582.
  3. Signorini M, Campiglio GL (March 1998). "Posttraumatic lipomas: where do they really come from?". Plast. Reconstr. Surg. 101 (3): 699–705. doi:10.1097/00006534-199803000-00017. PMID 9500386.
  4. Aust MC, Spies M, Kall S, Jokuszies A, Gohritz A, Vogt P (2007). "Posttraumatic lipoma: fact or fiction?". Skinmed. 6 (6): 266–70. doi:10.1111/j.1540-9740.2007.06361.x. PMID 17975353.


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