Aortitis medical therapy: Difference between revisions
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==Overview== | ==Overview== | ||
=== | ==Treatment== | ||
===Antimicrobial Regimen=== | |||
*Infectious aortitis | |||
:* Preferred regimen<ref name="pmid15935117">{{cite journal| author=Foote EA, Postier RG, Greenfield RA, Bronze MS| title=Infectious Aortitis. | journal=Curr Treat Options Cardiovasc Med | year= 2005 | volume= 7 | issue= 2 | pages= 89-97 | pmid=15935117 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15935117 }} </ref>(1): [[Cefotaxime sodium]] 1.0 to 2.0 g IV qd | :* Preferred regimen<ref name="pmid15935117">{{cite journal| author=Foote EA, Postier RG, Greenfield RA, Bronze MS| title=Infectious Aortitis. | journal=Curr Treat Options Cardiovasc Med | year= 2005 | volume= 7 | issue= 2 | pages= 89-97 | pmid=15935117 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15935117 }} </ref>(1): [[Cefotaxime sodium]] 1.0 to 2.0 g IV qd | ||
:* Preferred regimen (2): [[Ciprofloxacin hydrochloride]] 400 mg IV q12h {{or}} [[Ciprofloxacin hydrochloride]] 500 to 750 mg PO q12h {{or}} [[Levofloxacin]] 250 to 750 mg IV/PO qd | :* Preferred regimen (2): [[Ciprofloxacin hydrochloride]] 400 mg IV q12h {{or}} [[Ciprofloxacin hydrochloride]] 500 to 750 mg PO q12h {{or}} [[Levofloxacin]] 250 to 750 mg IV/PO qd | ||
Revision as of 20:48, 11 August 2015
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Treatment
Antimicrobial Regimen
- Infectious aortitis
- Preferred regimen[1](1): Cefotaxime sodium 1.0 to 2.0 g IV qd
- Preferred regimen (2): Ciprofloxacin hydrochloride 400 mg IV q12h OR Ciprofloxacin hydrochloride 500 to 750 mg PO q12h OR Levofloxacin 250 to 750 mg IV/PO qd
- Preferred regimen (3): Oxacillin 1.0 to 2.0g IV or IM q4h / q6h OR Nafcillin 1.0 to 2.0 g IV or IM q4h / q6h OR Dicloxacillin 500 mg to 1.0 g IV or IM q4h /q6h
- Preferred regimen (4): Vancomycin 1.0 g (15 mg/kg, up to 3.0 to 4.0 g/d) IV q12h
- Note: Antimicrobial treatments are most effective when bactericidal, broadspectrum antibiotics are begun after obtaining blood cultures and prior to surgery. Dose of Cefotaxime sodium should be decreased by 50% in those with a creatinine clearance (CCr) of ≤ 20 mL/min. Ciprofloxacin should be used cautiously in those with a CCr ≤ 50 mL/min or when given concomitantly with drugs whose metabolism may be altered.
References
- ↑ Foote EA, Postier RG, Greenfield RA, Bronze MS (2005). "Infectious Aortitis". Curr Treat Options Cardiovasc Med. 7 (2): 89–97. PMID 15935117.