Malabsorption other diagnostic studies: Difference between revisions
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{{Malabsorption}} | {{Malabsorption}} | ||
{{CMG}} | {{CMG}} | ||
==Overview== | |||
==Other Diagnostic Studies== | ==Other Diagnostic Studies== | ||
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[[Image:Coeliac path.jpg|thumb|left|Biopsy of [[small bowel]] showing coeliac disease manifested by blunting of [[villi]], crypt hyperplasia, and [[lymphocyte]] infiltration of crypts.]] | [[Image:Coeliac path.jpg|thumb|left|Biopsy of [[small bowel]] showing coeliac disease manifested by blunting of [[villi]], crypt hyperplasia, and [[lymphocyte]] infiltration of crypts.]] | ||
*Endoscopy is frequently undertaken, but to | *Endoscopy is frequently undertaken, but to visualizing the small intestine, which can be up to 7m long, is indeed a daunting task. | ||
**[[OGD]] to reveal duodenal lesion also for D2 biopsy. (for [[celiac disease]], [[tropical sprue]], [[whipple disease]], [[abetalipoproteinemia]] etc) | **[[OGD]] to reveal duodenal lesion also for D2 biopsy. (for [[celiac disease]], [[tropical sprue]], [[whipple disease]], [[abetalipoproteinemia]] etc) | ||
**[[Enteroscopy]] for enteropathy and jejunal aspirate and culture for bacterial overgrowth. | **[[Enteroscopy]] for enteropathy and jejunal aspirate and culture for bacterial overgrowth. | ||
**[[Colonoscopy]] is helpful in colonic or ileal lesion. | **[[Colonoscopy]] is helpful in colonic or ileal lesion. | ||
**[[ERCP]]: [[MRCP]] to complement or as an alternative to [[ERCP]] | **[[ERCP]]: [[MRCP]] to complement or as an alternative to [[ERCP]]. | ||
===Other Investigations=== | ===Other Investigations=== | ||
*[[Radionuclide|Radio isotope]] tests e.g. 75SeHCAT, 95mTc to exclude terminal ileal disease. | *[[Radionuclide|Radio isotope]] tests e.g. 75SeHCAT, 95mTc to exclude terminal ileal disease. | ||
*Sugar probes or sub 51Cr-EDTA to determine intestinal permeability<ref name="julio">{{cite journal |author=Bai J |title=Malabsorption syndromes |journal=Digestion |volume=59 |issue=5 |pages=530-46 |year=1998 |pmid=9705537}}</ref> | *Sugar probes or sub 51Cr-EDTA to determine intestinal permeability.<ref name="julio">{{cite journal |author=Bai J |title=Malabsorption syndromes |journal=Digestion |volume=59 |issue=5 |pages=530-46 |year=1998 |pmid=9705537}}</ref> | ||
*Glucose hydrogen breath test for [[bacterial overgrowth]] | *Glucose hydrogen breath test for [[bacterial overgrowth]]. | ||
*[[D-xylose]] absorption test | *[[D-xylose]] absorption test: Lower level in urine after ingestion indicates bacterial overgrowth or reduced absorptive surface, normal in pancreatic insufficiency. | ||
*Bile salt breath test to determine [[bile salt]] malabsorption. | *Bile salt breath test to determine [[bile salt]] malabsorption. | ||
*[[Schilling test]] to establish cause of B12 deficiency. | *[[Schilling test]] to establish cause of B12 deficiency. | ||
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==References== | ==References== | ||
{{Reflist|2}} | |||
[[Category:Disease]] | [[Category:Disease]] | ||
[[Category:Gastroenterology]] | [[Category:Gastroenterology]] | ||
[[Category:Needs overview]] | [[Category:Needs overview]] | ||
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Latest revision as of 14:00, 12 July 2016
|
Malabsorption |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Other Diagnostic Studies
Interventional Studies
- Endoscopy is frequently undertaken, but to visualizing the small intestine, which can be up to 7m long, is indeed a daunting task.
- OGD to reveal duodenal lesion also for D2 biopsy. (for celiac disease, tropical sprue, whipple disease, abetalipoproteinemia etc)
- Enteroscopy for enteropathy and jejunal aspirate and culture for bacterial overgrowth.
- Colonoscopy is helpful in colonic or ileal lesion.
- ERCP: MRCP to complement or as an alternative to ERCP.
Other Investigations
- Radio isotope tests e.g. 75SeHCAT, 95mTc to exclude terminal ileal disease.
- Sugar probes or sub 51Cr-EDTA to determine intestinal permeability.[1]
- Glucose hydrogen breath test for bacterial overgrowth.
- D-xylose absorption test: Lower level in urine after ingestion indicates bacterial overgrowth or reduced absorptive surface, normal in pancreatic insufficiency.
- Bile salt breath test to determine bile salt malabsorption.
- Schilling test to establish cause of B12 deficiency.
- Lactose H2 breath test for lactose intolerance.