Malabsorption other diagnostic studies: Difference between revisions

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{{Malabsorption}}
{{Malabsorption}}
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==Overview==


==Other Diagnostic Studies==
==Other Diagnostic Studies==
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[[Image:Coeliac path.jpg|thumb|left|Biopsy of [[small bowel]] showing coeliac disease manifested by blunting of [[villi]], crypt hyperplasia, and [[lymphocyte]] infiltration of crypts.]]
[[Image:Coeliac path.jpg|thumb|left|Biopsy of [[small bowel]] showing coeliac disease manifested by blunting of [[villi]], crypt hyperplasia, and [[lymphocyte]] infiltration of crypts.]]


*Endoscopy is frequently undertaken, but to visualize small intestine which can be up to 7m long is indeed a daunting task.
*Endoscopy is frequently undertaken, but to visualizing the small intestine, which can be up to 7m long, is indeed a daunting task.
**[[OGD]] to reveal duodenal lesion also for D2 biopsy. (for [[celiac disease]], [[tropical sprue]], [[whipple disease]], [[abetalipoproteinemia]] etc)
**[[OGD]] to reveal duodenal lesion also for D2 biopsy. (for [[celiac disease]], [[tropical sprue]], [[whipple disease]], [[abetalipoproteinemia]] etc)
**[[Enteroscopy]] for enteropathy and jejunal aspirate and culture for bacterial overgrowth.
**[[Enteroscopy]] for enteropathy and jejunal aspirate and culture for bacterial overgrowth.
**[[Colonoscopy]] is helpful in colonic or ileal lesion.
**[[Colonoscopy]] is helpful in colonic or ileal lesion.
**[[ERCP]]: [[MRCP]] to complement or as an alternative to [[ERCP]]
**[[ERCP]]: [[MRCP]] to complement or as an alternative to [[ERCP]].


===Other Investigations===
===Other Investigations===
*[[Radionuclide|Radio isotope]] tests e.g. 75SeHCAT, 95mTc to exclude terminal ileal disease.
*[[Radionuclide|Radio isotope]] tests e.g. 75SeHCAT, 95mTc to exclude terminal ileal disease.
*Sugar probes or sub 51Cr-EDTA to determine intestinal permeability<ref name="julio">{{cite journal |author=Bai J |title=Malabsorption syndromes |journal=Digestion |volume=59 |issue=5 |pages=530-46 |year=1998 |pmid=9705537}}</ref>.
*Sugar probes or sub 51Cr-EDTA to determine intestinal permeability.<ref name="julio">{{cite journal |author=Bai J |title=Malabsorption syndromes |journal=Digestion |volume=59 |issue=5 |pages=530-46 |year=1998 |pmid=9705537}}</ref>  
*Glucose hydrogen breath test for [[bacterial overgrowth]]
*Glucose hydrogen breath test for [[bacterial overgrowth]].
*[[D-xylose]] absorption test. lower level in urine after ingestion indicates bacterial overgrowth or reduced absorptive surface. normal in pancreatic insufficiency.
*[[D-xylose]] absorption test: Lower level in urine after ingestion indicates bacterial overgrowth or reduced absorptive surface, normal in pancreatic insufficiency.
*Bile salt breath test to determine [[bile salt]] malabsorption.
*Bile salt breath test to determine [[bile salt]] malabsorption.
*[[Schilling test]] to establish cause of B12 deficiency.
*[[Schilling test]] to establish cause of B12 deficiency.
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==References==
==References==
{{Reflist|2}}


{{Reflist|2}}
[[Category:Disease]]
[[Category:Disease]]
[[Category:Gastroenterology]]
[[Category:Gastroenterology]]
[[Category:Needs overview]]
[[Category:Needs overview]]
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Latest revision as of 14:00, 12 July 2016

Malabsorption

Home

Overview

Classification

Infection
Structural defect
Digestive failure
Systemic disease
Iatrogenic

Differentiating Malabsorption from other Diseases

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Other Diagnostic Studies

Interventional Studies

Biopsy of small bowel showing coeliac disease manifested by blunting of villi, crypt hyperplasia, and lymphocyte infiltration of crypts.

Other Investigations

  • Radio isotope tests e.g. 75SeHCAT, 95mTc to exclude terminal ileal disease.
  • Sugar probes or sub 51Cr-EDTA to determine intestinal permeability.[1]
  • Glucose hydrogen breath test for bacterial overgrowth.
  • D-xylose absorption test: Lower level in urine after ingestion indicates bacterial overgrowth or reduced absorptive surface, normal in pancreatic insufficiency.
  • Bile salt breath test to determine bile salt malabsorption.
  • Schilling test to establish cause of B12 deficiency.
  • Lactose H2 breath test for lactose intolerance.

References

  1. Bai J (1998). "Malabsorption syndromes". Digestion. 59 (5): 530–46. PMID 9705537.

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