SMG7: Difference between revisions

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<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{Infobox_gene}}
{{PBB_Controls
'''Protein SMG7''' is a [[protein]] that in humans is encoded by the ''SMG7'' [[gene]].<ref name="pmid14636577">{{cite journal | vauthors = Ohnishi T, Yamashita A, Kashima I, Schell T, Anders KR, Grimson A, Hachiya T, Hentze MW, Anderson P, Ohno S | title = Phosphorylation of hUPF1 induces formation of mRNA surveillance complexes containing hSMG-5 and hSMG-7 | journal = Mol Cell | volume = 12 | issue = 5 | pages = 1187–200 |date=Nov 2003 | pmid = 14636577 | pmc =  | doi =10.1016/S1097-2765(03)00443-X }}</ref><ref name="pmid15721257">{{cite journal | vauthors = Fukuhara N, Ebert J, Unterholzner L, Lindner D, Izaurralde E, Conti E | title = SMG7 is a 14-3-3-like adaptor in the nonsense-mediated mRNA decay pathway | journal = Mol Cell | volume = 17 | issue = 4 | pages = 537–47 |date=Feb 2005 | pmid = 15721257 | pmc =  | doi = 10.1016/j.molcel.2005.01.010 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: SMG7 Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9887| accessdate = }}</ref>
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<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image = PBB_Protein_SMG7_image.jpg
| image_source = [[Protein_Data_Bank|PDB]] rendering based on 1ya0.
| PDB = {{PDB2|1ya0}}
| Name = Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)
| HGNCid = 16792
| Symbol = SMG7
| AltSymbols =; C1orf16; EST1C; FLJ23717; KIAA0250; SGA56M; SMG-7
| OMIM =
| ECnumber =
| Homologene = 32235
| MGIid = 2682334
| GeneAtlas_image1 = PBB_GE_SMG7_201793_x_at_tn.png
| GeneAtlas_image2 = PBB_GE_SMG7_201794_s_at_tn.png
| GeneAtlas_image3 = PBB_GE_SMG7_217189_s_at_tn.png
  | Function = {{GNF_GO|id=GO:0005515 |text = protein binding}} {{GNF_GO|id=GO:0051721 |text = protein phosphatase 2A binding}}
  | Component = {{GNF_GO|id=GO:0005634 |text = nucleus}} {{GNF_GO|id=GO:0005737 |text = cytoplasm}}
| Process = {{GNF_GO|id=GO:0000184 |text = mRNA catabolic process, nonsense-mediated decay}} {{GNF_GO|id=GO:0006406 |text = mRNA export from nucleus}} {{GNF_GO|id=GO:0035303 |text = regulation of dephosphorylation}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 9887
    | Hs_Ensembl = ENSG00000116698
    | Hs_RefseqProtein = NP_055652
    | Hs_RefseqmRNA = NM_014837
    | Hs_GenLoc_db =   
    | Hs_GenLoc_chr = 1
    | Hs_GenLoc_start = 181708257
    | Hs_GenLoc_end = 181789948
    | Hs_Uniprot = Q92540
    | Mm_EntrezGene = 226517
    | Mm_Ensembl = ENSMUSG00000042772
    | Mm_RefseqmRNA = NM_001005507
    | Mm_RefseqProtein = NP_001005507
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 1
    | Mm_GenLoc_start = 154599214
    | Mm_GenLoc_end = 154640386
    | Mm_Uniprot = Q5RJH6
  }}
}}
'''Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)''', also known as '''SMG7''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: SMG7 Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9887| accessdate = }}</ref>


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==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal | author=Nakajima D, Okazaki N, Yamakawa H, ''et al.'' |title=Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. |journal=DNA Res. |volume=9 |issue= 3 |pages= 99-106 |year= 2003 |pmid= 12168954 |doi=  }}
*{{cite journal   |vauthors=Nakajima D, Okazaki N, Yamakawa H, etal |title=Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. |journal=DNA Res. |volume=9 |issue= 3 |pages= 99–106 |year= 2003 |pmid= 12168954 |doi=10.1093/dnares/9.3.99 }}
*{{cite journal | author=Nagase T, Seki N, Ishikawa K, ''et al.'' |title=Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain. |journal=DNA Res. |volume=3 |issue= 5 |pages= 321-9, 341-54 |year= 1997 |pmid= 9039502 |doi=  }}
*{{cite journal   |vauthors=Nagase T, Seki N, Ishikawa K, etal |title=Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain. |journal=DNA Res. |volume=3 |issue= 5 |pages= 321–9, 341–54 |year= 1997 |pmid= 9039502 |doi=10.1093/dnares/3.5.321 }}
*{{cite journal | author=Sood R, Bonner TI, Makalowska I, ''et al.'' |title=Cloning and characterization of 13 novel transcripts and the human RGS8 gene from the 1q25 region encompassing the hereditary prostate cancer (HPC1) locus. |journal=Genomics |volume=73 |issue= 2 |pages= 211-22 |year= 2001 |pmid= 11318611 |doi= 10.1006/geno.2001.6500 }}
*{{cite journal   |vauthors=Sood R, Bonner TI, Makalowska I, etal |title=Cloning and characterization of 13 novel transcripts and the human RGS8 gene from the 1q25 region encompassing the hereditary prostate cancer (HPC1) locus. |journal=Genomics |volume=73 |issue= 2 |pages= 211–22 |year= 2001 |pmid= 11318611 |doi= 10.1006/geno.2001.6500 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
*{{cite journal | author=Reichenbach P, Höss M, Azzalin CM, ''et al.'' |title=A human homolog of yeast Est1 associates with telomerase and uncaps chromosome ends when overexpressed. |journal=Curr. Biol. |volume=13 |issue= 7 |pages= 568-74 |year= 2003 |pmid= 12676087 |doi=  }}
*{{cite journal   |vauthors=Reichenbach P, Höss M, Azzalin CM, etal |title=A human homolog of yeast Est1 associates with telomerase and uncaps chromosome ends when overexpressed |journal=Curr. Biol. |volume=13 |issue= 7 |pages= 568–74 |year= 2003 |pmid= 12676087 |doi=10.1016/S0960-9822(03)00173-8 }}
*{{cite journal | author=Snow BE, Erdmann N, Cruickshank J, ''et al.'' |title=Functional conservation of the telomerase protein Est1p in humans. |journal=Curr. Biol. |volume=13 |issue= 8 |pages= 698-704 |year= 2004 |pmid= 12699629 |doi= }}
*{{cite journal   |vauthors=Snow BE, Erdmann N, Cruickshank J, etal |title=Functional conservation of the telomerase protein Est1p in humans |journal=Curr. Biol. |volume=13 |issue= 8 |pages= 698–704 |year= 2004 |pmid= 12699629 |doi=10.1016/S0960-9822(03)00210-0 }}
*{{cite journal  | author=Ohnishi T, Yamashita A, Kashima I, ''et al.'' |title=Phosphorylation of hUPF1 induces formation of mRNA surveillance complexes containing hSMG-5 and hSMG-7. |journal=Mol. Cell |volume=12 |issue= 5 |pages= 1187-200 |year= 2004 |pmid= 14636577 |doi= }}
*{{cite journal   |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal  | vauthors=Unterholzner L, Izaurralde E |title=SMG7 acts as a molecular link between mRNA surveillance and mRNA decay |journal=Mol. Cell |volume=16 |issue= 4 |pages= 587–96 |year= 2005 |pmid= 15546618 |doi= 10.1016/j.molcel.2004.10.013 }}
*{{cite journal  | author=Unterholzner L, Izaurralde E |title=SMG7 acts as a molecular link between mRNA surveillance and mRNA decay. |journal=Mol. Cell |volume=16 |issue= 4 |pages= 587-96 |year= 2005 |pmid= 15546618 |doi= 10.1016/j.molcel.2004.10.013 }}
*{{cite journal  | vauthors=Azzalin CM, Lingner J |title=The human RNA surveillance factor UPF1 is required for S phase progression and genome stability |journal=Curr. Biol. |volume=16 |issue= 4 |pages= 433–9 |year= 2006 |pmid= 16488880 |doi= 10.1016/j.cub.2006.01.018 }}
*{{cite journal  | author=Fukuhara N, Ebert J, Unterholzner L, ''et al.'' |title=SMG7 is a 14-3-3-like adaptor in the nonsense-mediated mRNA decay pathway. |journal=Mol. Cell |volume=17 |issue= 4 |pages= 537-47 |year= 2005 |pmid= 15721257 |doi= 10.1016/j.molcel.2005.01.010 }}
*{{cite journal   |vauthors=Gregory SG, Barlow KF, McLay KE, etal |title=The DNA sequence and biological annotation of human chromosome 1 |journal=Nature |volume=441 |issue= 7091 |pages= 315–21 |year= 2006 |pmid= 16710414 |doi= 10.1038/nature04727 }}
*{{cite journal  | author=Azzalin CM, Lingner J |title=The human RNA surveillance factor UPF1 is required for S phase progression and genome stability. |journal=Curr. Biol. |volume=16 |issue= 4 |pages= 433-9 |year= 2006 |pmid= 16488880 |doi= 10.1016/j.cub.2006.01.018 }}
*{{cite journal   |vauthors=Olsen JV, Blagoev B, Gnad F, etal |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks |journal=Cell |volume=127 |issue= 3 |pages= 635–48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026 }}
*{{cite journal | author=Gregory SG, Barlow KF, McLay KE, ''et al.'' |title=The DNA sequence and biological annotation of human chromosome 1. |journal=Nature |volume=441 |issue= 7091 |pages= 315-21 |year= 2006 |pmid= 16710414 |doi= 10.1038/nature04727 }}
*{{cite journal | author=Olsen JV, Blagoev B, Gnad F, ''et al.'' |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635-48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026 }}
}}
}}
{{refend}}
{{refend}}
{{PDB Gallery|geneid=9887}}
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{{protein-stub}}
{{gene-1-stub}}
{{WikiDoc Sources}}

Latest revision as of 21:34, 19 February 2018

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Protein SMG7 is a protein that in humans is encoded by the SMG7 gene.[1][2][3]


References

  1. Ohnishi T, Yamashita A, Kashima I, Schell T, Anders KR, Grimson A, Hachiya T, Hentze MW, Anderson P, Ohno S (Nov 2003). "Phosphorylation of hUPF1 induces formation of mRNA surveillance complexes containing hSMG-5 and hSMG-7". Mol Cell. 12 (5): 1187–200. doi:10.1016/S1097-2765(03)00443-X. PMID 14636577.
  2. Fukuhara N, Ebert J, Unterholzner L, Lindner D, Izaurralde E, Conti E (Feb 2005). "SMG7 is a 14-3-3-like adaptor in the nonsense-mediated mRNA decay pathway". Mol Cell. 17 (4): 537–47. doi:10.1016/j.molcel.2005.01.010. PMID 15721257.
  3. "Entrez Gene: SMG7 Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)".

Further reading