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{{Infobox_gene}}
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'''Olfactory receptor 52A1''' is a [[protein]] that in humans is encoded by the ''OR52A1'' [[gene]].<ref name="pmid10512676">{{cite journal | vauthors = Feingold EA, Penny LA, Nienhuis AW, Forget BG | title = An olfactory receptor gene is located in the extended human beta-globin gene cluster and is expressed in erythroid cells | journal = Genomics | volume = 61 | issue = 1 | pages = 15–23 |date=Nov 1999 | pmid = 10512676 | pmc =  | doi = 10.1006/geno.1999.5935 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: OR52A1 olfactory receptor, family 52, subfamily A, member 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23538| accessdate = }}</ref>
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| image = 
| image_source = 
| PDB =
| Name = Olfactory receptor, family 52, subfamily A, member 1
| HGNCid = 8318
| Symbol = OR52A1
| AltSymbols =; HPFH1OR
| OMIM = 
| ECnumber = 
| Homologene = 85928
| MGIid = 
| GeneAtlas_image1 = PBB_GE_OR52A1_221329_at_tn.png
| Function = {{GNF_GO|id=GO:0004984 |text = olfactory receptor activity}}
| Component = {{GNF_GO|id=GO:0005887 |text = integral to plasma membrane}} {{GNF_GO|id=GO:0016020 |text = membrane}}
| Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0007608 |text = sensory perception of smell}} {{GNF_GO|id=GO:0050896 |text = response to stimulus}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 23538
    | Hs_Ensembl = ENSG00000182070
    | Hs_RefseqProtein = NP_036507
    | Hs_RefseqmRNA = NM_012375
    | Hs_GenLoc_db =   
    | Hs_GenLoc_chr = 11
    | Hs_GenLoc_start = 5128815
    | Hs_GenLoc_end = 5164188
    | Hs_Uniprot = Q9UKL2
    | Mm_EntrezGene = 
    | Mm_Ensembl = 
    | Mm_RefseqmRNA = 
    | Mm_RefseqProtein = 
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 
    | Mm_GenLoc_start = 
    | Mm_GenLoc_end = 
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'''Olfactory receptor, family 52, subfamily A, member 1''', also known as '''OR52A1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: OR52A1 olfactory receptor, family 52, subfamily A, member 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23538| accessdate = }}</ref>


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{{PBB_Summary
{{PBB_Summary
| section_title =  
| section_title =  
| summary_text = Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.<ref name="entrez">{{cite web | title = Entrez Gene: OR52A1 olfactory receptor, family 52, subfamily A, member 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23538| accessdate = }}</ref>
| summary_text = Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.<ref name="entrez">{{cite web | title = Entrez Gene: OR52A1 olfactory receptor, family 52, subfamily A, member 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23538| accessdate = }}</ref>
}}
}}


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==References==
==References==
{{reflist|2}}
{{reflist}}


==Further reading==
==Further reading==
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| citations =  
| citations =  
*{{cite journal | author=Feingold EA, Penny LA, Nienhuis AW, Forget BG |title=An olfactory receptor gene is located in the extended human beta-globin gene cluster and is expressed in erythroid cells. |journal=Genomics |volume=61 |issue= 1 |pages= 15-23 |year= 1999 |pmid= 10512676 |doi= 10.1006/geno.1999.5935 }}
*{{cite journal   |vauthors=Bulger M, Bender MA, van Doorninck JH, etal |title=Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse beta-globin gene clusters. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=97 |issue= 26 |pages= 14560–5 |year= 2001 |pmid= 11121057 |doi= 10.1073/pnas.97.26.14560 | pmc=18958 }}
*{{cite journal  | author=Bulger M, Bender MA, van Doorninck JH, ''et al.'' |title=Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse beta-globin gene clusters. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=97 |issue= 26 |pages= 14560-5 |year= 2001 |pmid= 11121057 |doi= 10.1073/pnas.97.26.14560 }}
*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | vauthors=Malnic B, Godfrey PA, Buck LB |title=The human olfactory receptor gene family. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 8 |pages= 2584–9 |year= 2004 |pmid= 14983052 |doi=10.1073/pnas.0307882100  | pmc=356993 }}
*{{cite journal  | author=Malnic B, Godfrey PA, Buck LB |title=The human olfactory receptor gene family. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 8 |pages= 2584-9 |year= 2004 |pmid= 14983052 |doi=  }}
*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
}}
}}
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{{NLM content}}
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{{Olfactory receptors}}
{{Olfactory receptors}}
[[Category:G protein coupled receptors]]
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Latest revision as of 00:31, 7 September 2017

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SpeciesHumanMouse
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RefSeq (mRNA)

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Wikidata
View/Edit Human

Olfactory receptor 52A1 is a protein that in humans is encoded by the OR52A1 gene.[1][2]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[2]

See also

References

  1. ↑ Feingold EA, Penny LA, Nienhuis AW, Forget BG (Nov 1999). "An olfactory receptor gene is located in the extended human beta-globin gene cluster and is expressed in erythroid cells". Genomics. 61 (1): 15–23. doi:10.1006/geno.1999.5935. PMID 10512676.
  2. ↑ 2.0 2.1 "Entrez Gene: OR52A1 olfactory receptor, family 52, subfamily A, member 1".

Further reading

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.



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