Differentiating Ewing's sarcoma from other diseases: Difference between revisions

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{{Ewing's sarcoma}}
__NOTOC__
{{CMG}}; '''Assistant Editor(s)-In-Chief:''' [[User:Michael Maddaleni|Michael Maddaleni, B.S.]]
[[Image:Home_logo1.png|right|250px|link=http://www.wikidoc.org/index.php/Ewing%27s_sarcoma]]
{{CMG}};{{AE}} {{PSK}}; '''Assistant Editor(s)-In-Chief:''' [[User:Michael Maddaleni|Michael Maddaleni, B.S.]]


==Overview==
==Overview==
Ewing's sarcoma must be differentiated from [[osteosarcoma]], hematological malignancy, [[eosinophilic granuloma]], and [[malignant fibrous histiocytoma]].<ref name=radiopaedia>Ewing's sarcoma. Dr Amir Rezaee◉ and Dr Frank Gaillard◉ et al.Radiopaedia.org 2015. http://radiopaedia.org/articles/ewing-sarcoma</ref>


===Similar presentation===
==Differentiating Ewing's sarcoma from other diseases==
Other entities that may have a similar radiologic presentation include osteomyelitis, [[osteosarcoma]] (especially telangiectatic osteosarcoma) and eosinophilic granuloma. Soft tissue neoplasms such as malignant fibrous histiocytoma that erode into adjacent bone may also have a similar appearance.
Ewing's sarcoma must be differentiated from:<ref name=radiopaedia>Ewing's sarcoma. Dr Amir Rezaee◉ and Dr Frank Gaillard◉ et al.Radiopaedia.org 2015. http://radiopaedia.org/articles/ewing-sarcoma</ref>
 
*[[Osteosarcoma]]
===Common Ewing's sarcoma findings===
:*ALP is not elevated in Ewing sarcoma.
Ewing's sarcomas are commonly found in the [[trunk]] and [[long bones]]. Therefore, they are commonly found in the [[pelvic]] region, [[clavicles]], [[scapulas]], [[vertebral column]], and [[ribs]]. The most common bone for this to occur in is the [[femur]], followed by the [[humerus]] and [[tibia]].<ref name="pmid17272319">{{cite journal |author=Iwamoto Y |title=Diagnosis and treatment of Ewing's sarcoma |journal=[[Japanese Journal of Clinical Oncology]] |volume=37 |issue=2 |pages=79–89 |year=2007 |month=February |pmid=17272319 |doi=10.1093/jjco/hyl142 |url=http://jjco.oxfordjournals.org/cgi/pmidlookup?view=long&pmid=17272319 |accessdate=2011-12-21}}</ref> Ewing's sarcoma tends to arise from the[[diaphysis]] whereas in osteosarcoma it tends to arise from the [[metaphysis]]. It should also be noted that Ewing's sarcoma has a strong potential to [[metastasize]].
:* Ewing sarcoma tends to arise from the [[diaphysis]] whereas in osteosarcoma it tends to arise from the [[metaphysis]].
*Osteomyelitis
*Hematological malignancy
:*[[Lymphoma|Large cell lymphoma]]
*[[Eosinophilic granuloma]]
*[[Malignant fibrous histiocytoma]]


==References==
==References==
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[[Category:Orthopedics]]
[[Category:Orthopedics]]
[[Category:Types of cancer]]
[[Category:Types of cancer]]
[[Category:Mature chapter]]
[[Category:Up-To-Date]]
[[Category:Oncology]]
[[Category:Oncology]]
[[Category:Mature chapter]]
[[Category:Medicine]]
[[Category:Orthopedics]]

Latest revision as of 22:29, 20 February 2019

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Suveenkrishna Pothuru, M.B,B.S. [2]; Assistant Editor(s)-In-Chief: Michael Maddaleni, B.S.

Overview

Ewing's sarcoma must be differentiated from osteosarcoma, hematological malignancy, eosinophilic granuloma, and malignant fibrous histiocytoma.[1]

Differentiating Ewing's sarcoma from other diseases

Ewing's sarcoma must be differentiated from:[1]

  • ALP is not elevated in Ewing sarcoma.
  • Ewing sarcoma tends to arise from the diaphysis whereas in osteosarcoma it tends to arise from the metaphysis.
  • Osteomyelitis
  • Hematological malignancy

References

  1. ↑ 1.0 1.1 Ewing's sarcoma. Dr Amir Rezaee◉ and Dr Frank Gaillard◉ et al.Radiopaedia.org 2015. http://radiopaedia.org/articles/ewing-sarcoma

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