THOC1: Difference between revisions

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{{Infobox_gene}}
{{Infobox_gene}}
'''THO complex subunit 1''' is a [[protein]] that in humans is encoded by the ''THOC1'' [[gene]].<ref name="pmid11979277">{{cite journal |vauthors=Strasser K, Masuda S, Mason P, Pfannstiel J, Oppizzi M, Rodriguez-Navarro S, Rondon AG, Aguilera A, Struhl K, Reed R, Hurt E | title = TREX is a conserved complex coupling transcription with messenger RNA export | journal = Nature | volume = 417 | issue = 6886 | pages = 304–8 |date=May 2002 | pmid = 11979277 | pmc =  | doi = 10.1038/nature746 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: THOC1 THO complex 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9984| accessdate = }}</ref>
'''THO complex subunit 1''' is a [[protein]] that in humans is encoded by the ''THOC1'' [[gene]].<ref name="pmid11979277">{{cite journal |vauthors=Strasser K, Masuda S, Mason P, Pfannstiel J, Oppizzi M, Rodriguez-Navarro S, Rondon AG, Aguilera A, Struhl K, Reed R, Hurt E | title = TREX is a conserved complex coupling transcription with messenger RNA export | journal = Nature | volume = 417 | issue = 6886 | pages = 304–8 |date=May 2002 | pmid = 11979277 | pmc =  | doi = 10.1038/nature746 | bibcode =2002Natur.417..304S }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: THOC1 THO complex 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9984| accessdate = }}</ref>


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* {{cite journal  |vauthors=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1–2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=10.1016/0378-1119(94)90802-8  }}
* {{cite journal  |vauthors=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1–2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=10.1016/0378-1119(94)90802-8  }}
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* {{cite journal  |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
* {{cite journal  |vauthors=Dennehey BK, Gutches DG, McConkey EH, Krauter KS |title=Inversion, duplication, and changes in gene context are associated with human chromosome 18 evolution. |journal=Genomics |volume=83 |issue= 3 |pages= 493–501 |year= 2004 |pmid= 14962675 |doi= 10.1016/j.ygeno.2003.08.017 }}
* {{cite journal  |vauthors=Dennehey BK, Gutches DG, McConkey EH, Krauter KS |title=Inversion, duplication, and changes in gene context are associated with human chromosome 18 evolution. |journal=Genomics |volume=83 |issue= 3 |pages= 493–501 |year= 2004 |pmid= 14962675 |doi= 10.1016/j.ygeno.2003.08.017 }}
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* {{cite journal  |vauthors=Beausoleil SA, Jedrychowski M, Schwartz D, etal |title=Large-scale characterization of HeLa cell nuclear phosphoproteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 33 |pages= 12130–5 |year= 2004 |pmid= 15302935 |doi= 10.1073/pnas.0404720101  | pmc=514446 |bibcode=2004PNAS..10112130B }}
* {{cite journal  |vauthors=Gasparri F, Sola F, Locatelli G, Muzio M |title=The death domain protein p84N5, but not the short isoform p84N5s, is cell cycle-regulated and shuttles between the nucleus and the cytoplasm. |journal=FEBS Lett. |volume=574 |issue= 1–3 |pages= 13–9 |year= 2004 |pmid= 15358532 |doi= 10.1016/j.febslet.2004.07.074 }}
* {{cite journal  |vauthors=Gasparri F, Sola F, Locatelli G, Muzio M |title=The death domain protein p84N5, but not the short isoform p84N5s, is cell cycle-regulated and shuttles between the nucleus and the cytoplasm. |journal=FEBS Lett. |volume=574 |issue= 1–3 |pages= 13–9 |year= 2004 |pmid= 15358532 |doi= 10.1016/j.febslet.2004.07.074 }}
* {{cite journal  |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504  | pmc=528928 }}
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* {{cite journal  |vauthors=Li Y, Wang X, Zhang X, Goodrich DW |title=Human hHpr1/p84/Thoc1 regulates transcriptional elongation and physically links RNA polymerase II and RNA processing factors. |journal=Mol. Cell. Biol. |volume=25 |issue= 10 |pages= 4023–33 |year= 2005 |pmid= 15870275 |doi= 10.1128/MCB.25.10.4023-4033.2005  | pmc=1087710 }}
* {{cite journal  |vauthors=Li Y, Wang X, Zhang X, Goodrich DW |title=Human hHpr1/p84/Thoc1 regulates transcriptional elongation and physically links RNA polymerase II and RNA processing factors. |journal=Mol. Cell. Biol. |volume=25 |issue= 10 |pages= 4023–33 |year= 2005 |pmid= 15870275 |doi= 10.1128/MCB.25.10.4023-4033.2005  | pmc=1087710 }}
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* {{cite journal  |vauthors=Rual JF, Venkatesan K, Hao T, etal |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
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Latest revision as of 09:03, 9 January 2019

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

THO complex subunit 1 is a protein that in humans is encoded by the THOC1 gene.[1][2]

HPR1 is part of the TREX (transcription/export) complex, which includes TEX1 (MIM 606929), THO2 (MIM 300395), ALY (MIM 604171), and UAP56 (MIM 606390).[supplied by OMIM][2]

Interactions

THOC1 has been shown to interact with Retinoblastoma protein.[3]

References

  1. Strasser K, Masuda S, Mason P, Pfannstiel J, Oppizzi M, Rodriguez-Navarro S, Rondon AG, Aguilera A, Struhl K, Reed R, Hurt E (May 2002). "TREX is a conserved complex coupling transcription with messenger RNA export". Nature. 417 (6886): 304–8. Bibcode:2002Natur.417..304S. doi:10.1038/nature746. PMID 11979277.
  2. 2.0 2.1 "Entrez Gene: THOC1 THO complex 1".
  3. Durfee, T; Mancini M A; Jones D; Elledge S J; Lee W H (November 1994). "The amino-terminal region of the retinoblastoma gene product binds a novel nuclear matrix protein that co-localizes to centers for RNA processing". J. Cell Biol. UNITED STATES. 127 (3): 609–22. doi:10.1083/jcb.127.3.609. ISSN 0021-9525. PMC 2120229. PMID 7525595.

Further reading