Molluscum contagiosum epidemiology and demographics: Difference between revisions

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{{Molluscum contagiosum}}
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==Overview==
==Overview==
 
The prevalence of molluscum contagiosum is estimated to be around 8000 cases per 100,000 annually. Molluscum contagiosum is a common disease that tends to affect children and [[immunocompromised]] adults. Among children, boys and girls are affected equally by molluscum contagiosum. In adulthood, molluscum contagiosum is more prevalent in men than women . There is no racial predilection to molluscum contagiosum.  
:In [year], the incidence/prevalence of [disease name] was estimated to be [number range] cases per 100,000 individuals worldwide.
:OR
:The prevalence of [disease/malignancy] is estimated to be [number] cases annually.
:OR
:[Cancer name] is the [number] most common cancer worldwide.
 
*'''Additional Sentences''':
:Additional Sentence 1: The case-mortality rate of [disease name] is approximately [number range] worldwide.
:Additional Sentence 2: The majority of [disease name] cases are reported in [geographical region].
:Additional Sentence 3: Patients of all age groups may develop [disease name]
:Additional Sentence 4: [Disease name] is a common/rare disease that tends to affect [patient population 1] and [patient population 2].
:Additional Sentence 5: [Gender 1] are more commonly affected with [disease name] than [gender 2]. The [gender 1] to [gender 2] ratio is approximately [number > 1] to 1.
:Additional Sentence 6: [Disease name] affects men and women equally.
:Additional Sentence 7: There is no racial predilection to [disease name].
:Additional Sentence 8: [Disease name] usually affects individuals of the [ethnicity 1] race. [Ethnicity 2] individuals are less likely to develop [disease name].
:Additional Sentence 9: The incidence of [disease name] increases with age; the median age at diagnosis is [#] years.
:Additional Sentence 10: [Chronic disease name] is usually first diagnosed among [age group].
:Additional Sentence 11: [Acute disease name] commonly affects  [age group].
:Additional Sentence 12: [Disease name] commonly affects individuals younger than/older than [number of years] years of age.


==Epidemiology and Demographics==
==Epidemiology and Demographics==
===Prevalence===
* Worldwide, the prevalence of molluscum contagiosum in children aged 0-16 year ranges from  5000 to 11500 per 100,000 persons with an average prevalence of 8000 per 100,000 persons.<ref name="pmid24297468">{{cite journal |vauthors=Olsen JR, Gallacher J, Piguet V, Francis NA |title=Epidemiology of molluscum contagiosum in children: a systematic review |journal=Fam Pract |volume=31 |issue=2 |pages=130–6 |year=2014 |pmid=24297468 |doi=10.1093/fampra/cmt075 |url=}}</ref>


===Prevalence===
*Prevalence is defined as the total number of cases of a disease in a given at-risk population at a specific time.
:Note: For diseases specific to one gender, such as prostate cancer, only male patients are considered in the equation since only male patients are the at-risk population.
*When using numbers with decimal points, avoid reporting more than 1 number after the decimal point. For example, report a prevalence as 10.1 instead of 10.09322. Many numbers after the decimal point may suggest a false sense of accuracy.
*You can use one or more of these template sentences.
**Worldwide, the prevalence of (insert disease state here) ranges from a low of _____ per 100,000 persons  to a high of _____ per 100,000 persons with an average prevalence of _____ per 100,000 persons.
**Worldwide, the prevalence of (insert disease state here) is _____ per 100,000 persons.
**In developed countries, the prevalence of (insert disease state here) ranges from a low of _____ per 100,000 persons  to a high of _____ per 100,000 persons with an average prevalence of _____ per 100,000 persons.
**In developed countries, the prevalence of (insert disease state here) is _____ per 100,000 persons.
**In developing countries/ Africa, the prevalence of (insert disease state here) ranges from a low of _____ per 100,000 persons  to a high of _____ per 100,000 persons with an average prevalence of _____ per 100,000 persons.
**In developing countries/ Africa, the prevalence of (insert disease state here) is _____ per 100,000 persons.
**In ____ (insert year), the prevalence of _______ (insert disease name) was estimated to be _______ (insert number) cases per 100,000 individuals worldwide.
===Incidence===
===Incidence===
*Incidence is defined as the number of new cases per population in a given time period.
* Worldwide, the incidence of molluscum contagiosum is 1200-1400 per 100,000 persons per year.<ref name="pmid24297468">{{cite journal |vauthors=Olsen JR, Gallacher J, Piguet V, Francis NA |title=Epidemiology of molluscum contagiosum in children: a systematic review |journal=Fam Pract |volume=31 |issue=2 |pages=130–6 |year=2014 |pmid=24297468 |doi=10.1093/fampra/cmt075 |url=}}</ref>
*The standard format to report the incidence is ___ per 100,000 individuals.
* Outbreaks of molluscum contagiosum have occurred in different settings like swimming pools, but the exact information about outbreaks is not available due to the subclinical manifestations leading to under reporting.
*When using numbers with decimal points, avoid reporting more than 1 number after the decimal point. For example, report a incidence as 10.1 instead of 10.09322. Many numbers after the decimal point may suggest a false sense of accuracy.
 
*You can pick one or more of the template sentences below for this section:
**Worldwide, the incidence of (insert disease state here) ranges from a low of _____ per 100,000 persons to a high of _____ per 100,000 persons with an average incidence of _____ per 100,000 persons.
**Worldwide, the incidence of (insert disease state here) is _____ per 100,000 persons.
**In developed countries, the incidence of (insert disease state here) ranges from a low of _____ per 100,000 persons  to a high of _____ per 100,000 persons with an average incidence of _____ per 100,000 persons.
**In developed countries, the incidence of (insert disease state here) is _____ per 100,000 persons.
**In developing countries/ Africa, the incidence of (insert disease state here) ranges from a low of _____ per 100,000 persons  to a high of _____ per 100,000 persons with an average incidence of _____ per 100,000 persons.
**In developing countries/ Africa, the incidence of (insert disease state here) is _____ per 100,000 persons.
**In ____ (insert year), the incidence of _______ (insert disease name) was estimated to be _______ (insert number) cases per 100,000 individuals worldwide.
===Case Fatality Rate===
===Case Fatality Rate===
*The case fatality rate is defined the number of deaths (fatality) among patients with the disease (case). Case fatality rate should be distinguished from "Mortality Rate" (defined as the number of deaths among the at-risk population).
* Data on the case fatality rate of molluscum contagiosum is not available. Molluscum contagiosum only can lead to fatality in [[immunocompromised]] adults, which may be associated with other [[Opportunistic infection|opportunistic infections]] and thus the [[fatality rate]] is difficult to determine.<ref name="pmid10210787">{{cite journal |vauthors=Calista D, Boschini A, Landi G |title=Resolution of disseminated molluscum contagiosum with Highly Active Anti-Retroviral Therapy (HAART) in patients with AIDS |journal=Eur J Dermatol |volume=9 |issue=3 |pages=211–3 |year=1999 |pmid=10210787 |doi= |url=}}</ref><ref name="pmid1610701">{{cite journal |vauthors=Koopman RJ, van Merriënboer FC, Vreden SG, Dolmans WM |title=Molluscum contagiosum; a marker for advanced HIV infection |journal=Br. J. Dermatol. |volume=126 |issue=5 |pages=528–9 |year=1992 |pmid=1610701 |doi= |url=}}</ref>
*The case fatality rate is usually described as a function of time (e.g. In 2015 / annually etc...).
 
*When using numbers with decimal points, avoid reporting more than 1 number after the decimal point. For example, report the case fatality rate as 10.1% instead of 10.09322%. Many numbers after the decimal point may suggest a false sense of accuracy.
*You can pick the template sentence below for this section:
**In ____ (year), the case fatality rate of ____ (disease name) is ____ (case fatality rate in %).
**The annual case fatality rate of ____ (disease name) is approximately ____ (case fatality rate in %).
===Age===
===Age===
*This section can describe the impact of the disease depending on the persons age, and the age-specific prevalence and incidence.
*The prevalence of ____ (insert disease state here) increases/decreases with age.
*The prevalence of molluscum contagiosum decreases with age.<ref name="pmid28521677">{{cite journal |vauthors=Leung AK, Barankin B, Hon KL |title=Molluscum contagiosum: an update |journal=Recent Pat Inflamm Allergy Drug Discov |volume= |issue= |pages= |year=2017 |pmid=28521677 |doi=10.2174/1872213X11666170518114456 |url=}}</ref><ref name="pmid24297468">{{cite journal |vauthors=Olsen JR, Gallacher J, Piguet V, Francis NA |title=Epidemiology of molluscum contagiosum in children: a systematic review |journal=Fam Pract |volume=31 |issue=2 |pages=130–6 |year=2014 |pmid=24297468 |doi=10.1093/fampra/cmt075 |url=}}</ref><ref name="pmid16384754">{{cite journal |vauthors=Dohil MA, Lin P, Lee J, Lucky AW, Paller AS, Eichenfield LF |title=The epidemiology of molluscum contagiosum in children |journal=J. Am. Acad. Dermatol. |volume=54 |issue=1 |pages=47–54 |year=2006 |pmid=16384754 |doi=10.1016/j.jaad.2005.08.035 |url=}}</ref>
*_____ (insert acute disease) commonly affects _____ (insert age group).
*Incidence first peaks in preschool/school-aged children, with the greatest incidence being in those aged 1-4 years.<ref name="pmid25161331">{{cite journal |vauthors=Kalasannavar SB, Sawalgimath MP |title=Molluscum contagiosum: A novel Ayurvedic approach |journal=Anc Sci Life |volume=33 |issue=1 |pages=49–51 |year=2013 |pmid=25161331 |pmc=4140023 |doi=10.4103/0257-7941.134606 |url=}}</ref>
*_____ (insert chronic disease) is usually first diagnosed among _____ (insert age group).
*If diagnosed in adults, molluscum contagiosum will most commonly be seen in the 18 to 20 year age group.<ref name="pmid14996374">{{cite journal |vauthors=Laxmisha C, Thappa DM, Jaisankar TJ |title=Clinical profile of molluscum contagiosum in children versus adults |journal=Dermatol. Online J. |volume=9 |issue=5 |pages=1 |year=2003 |pmid=14996374 |doi= |url=}}</ref>
*Incidence first peaks in preschool children. PMC4140023
===Gender===
===Gender===
This section describe how prevalence of the disease varies by gender. When describing male to female ratios with decimal points, avoid reporting more than 1 number after the decimal point. For example, report a ratio as as 1.5 to 1 instead of 1.48294 to 1. Many numbers after the decimal point may suggest a false sense of accuracy. You can use either of the following template sentences:
*Among children, boys and girls are affected equally by molluscum contagiosum.
*______ (insert gender 1) are more commonly affected with ______ (insert disease name) than _____ (insert gender 2). The _____ (insert gender ratio e.g. male to female) ratio is approximately _____ (insert number > 1) to 1.
*In adulthood, molluscum contagiosum is more prevalent in men than in women .
*The prevalence and incidence of (insert disease state here) does not vary by gender.
*The male to female ratio is approximately 3 to 1 <ref name="pmid6687557">{{cite journal |vauthors= |title=Sexually transmitted diseases. Extract from the annual report of the Chief Medical Officer of the Department of Health and Social Security of the year 1980 |journal=Br J Vener Dis |volume=59 |issue=2 |pages=134–7 |year=1983 |pmid=6687557 |pmc=1046157 |doi= |url=}}</ref>A high proportion of the studied subjects were HIV-positive adults.<ref name="pmid5921341">{{cite journal |vauthors=Overfield TM, Brody JA |title=An epidemiologic study of molluscum contagiosum in Anchorage, Alaska |journal=J. Pediatr. |volume=69 |issue=4 |pages=640–2 |year=1966 |pmid=5921341 |doi= |url=}}</ref><ref name="pmid7928025">{{cite journal |vauthors=Gottlieb SL, Myskowski PL |title=Molluscum contagiosum |journal=Int. J. Dermatol. |volume=33 |issue=7 |pages=453–61 |year=1994 |pmid=7928025 |doi= |url=}}</ref>
*Men and women are affected equally by (insert disease name here).
*(Insert disease state here) is more prevalent in men women.
*The prevalence of (insert disease state here) among men is ____ per 100,000, while it is _____ per 100,000 among women.
*The incidence of (insert disease state here) among men is ____ per 100,000, while it is _____ per 100,000 among women.
===Race===
===Race===
This section describes how the disease differs based upon race. You can use the following template sentence for this section:
* There is no racial predilection to molluscum contagiosum.<ref name="pmid9952381">{{cite journal |vauthors=Konya J, Thompson CH |title=Molluscum contagiosum virus: antibody responses in persons with clinical lesions and seroepidemiology in a representative Australian population |journal=J. Infect. Dis. |volume=179 |issue=3 |pages=701–4 |year=1999 |pmid=9952381 |doi=10.1086/314620 |url=}}</ref>
*The prevalence of _____ (insert disease) does not vary by race.
 
*(Insert disease state here) is more prevalent in the ____ (inser race) race and ____ (insert other race) races.
===Geographic Distribution===
*There is no racial predilection for ____ (insert disease name)
* There are no geographic predispositions to molluscum contagiosum.
*_____ (insert disease) usually affects individuals of the _____ (inser race) race. _____ (insert other race) individuals are less likely to develop ______ (disease name).
===Developed Countries===
*In this section you should describe the impact of the disease in developed countries.
*Incidence, prevalence, and geographical distribution or areas of interest can be mentioned, as well as the relevant impact the disease has on society.
===Developing Countries===
*In this section you should describe the impact of the disease in developing countries.
*Incidence, prevalence, and geographical distribution or areas of interest can be mentioned, as well as the relevant impact the disease has on society.


==References==
==References==
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[[Category:Poxviruses]]
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Latest revision as of 22:45, 29 July 2020

Molluscum contagiosum Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Molluscum contagiosum from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic criteria

History and Symptoms

Physical Examination

Laboratory Findings

X ray

Ultrasound

CT Scan

MRI

Other Imaging Studies

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mahshid Mir, M.D. [2]

Overview

The prevalence of molluscum contagiosum is estimated to be around 8000 cases per 100,000 annually. Molluscum contagiosum is a common disease that tends to affect children and immunocompromised adults. Among children, boys and girls are affected equally by molluscum contagiosum. In adulthood, molluscum contagiosum is more prevalent in men than women . There is no racial predilection to molluscum contagiosum.

Epidemiology and Demographics

Prevalence

  • Worldwide, the prevalence of molluscum contagiosum in children aged 0-16 year ranges from 5000 to 11500 per 100,000 persons with an average prevalence of 8000 per 100,000 persons.[1]

Incidence

  • Worldwide, the incidence of molluscum contagiosum is 1200-1400 per 100,000 persons per year.[1]
  • Outbreaks of molluscum contagiosum have occurred in different settings like swimming pools, but the exact information about outbreaks is not available due to the subclinical manifestations leading to under reporting.

Case Fatality Rate

Age

  • The prevalence of molluscum contagiosum decreases with age.[4][1][5]
  • Incidence first peaks in preschool/school-aged children, with the greatest incidence being in those aged 1-4 years.[6]
  • If diagnosed in adults, molluscum contagiosum will most commonly be seen in the 18 to 20 year age group.[7]

Gender

  • Among children, boys and girls are affected equally by molluscum contagiosum.
  • In adulthood, molluscum contagiosum is more prevalent in men than in women .
  • The male to female ratio is approximately 3 to 1 [8]. A high proportion of the studied subjects were HIV-positive adults.[9][10]

Race

  • There is no racial predilection to molluscum contagiosum.[11]

Geographic Distribution

  • There are no geographic predispositions to molluscum contagiosum.

References

  1. 1.0 1.1 1.2 Olsen JR, Gallacher J, Piguet V, Francis NA (2014). "Epidemiology of molluscum contagiosum in children: a systematic review". Fam Pract. 31 (2): 130–6. doi:10.1093/fampra/cmt075. PMID 24297468.
  2. Calista D, Boschini A, Landi G (1999). "Resolution of disseminated molluscum contagiosum with Highly Active Anti-Retroviral Therapy (HAART) in patients with AIDS". Eur J Dermatol. 9 (3): 211–3. PMID 10210787.
  3. Koopman RJ, van Merriënboer FC, Vreden SG, Dolmans WM (1992). "Molluscum contagiosum; a marker for advanced HIV infection". Br. J. Dermatol. 126 (5): 528–9. PMID 1610701.
  4. Leung AK, Barankin B, Hon KL (2017). "Molluscum contagiosum: an update". Recent Pat Inflamm Allergy Drug Discov. doi:10.2174/1872213X11666170518114456. PMID 28521677.
  5. Dohil MA, Lin P, Lee J, Lucky AW, Paller AS, Eichenfield LF (2006). "The epidemiology of molluscum contagiosum in children". J. Am. Acad. Dermatol. 54 (1): 47–54. doi:10.1016/j.jaad.2005.08.035. PMID 16384754.
  6. Kalasannavar SB, Sawalgimath MP (2013). "Molluscum contagiosum: A novel Ayurvedic approach". Anc Sci Life. 33 (1): 49–51. doi:10.4103/0257-7941.134606. PMC 4140023. PMID 25161331.
  7. Laxmisha C, Thappa DM, Jaisankar TJ (2003). "Clinical profile of molluscum contagiosum in children versus adults". Dermatol. Online J. 9 (5): 1. PMID 14996374.
  8. "Sexually transmitted diseases. Extract from the annual report of the Chief Medical Officer of the Department of Health and Social Security of the year 1980". Br J Vener Dis. 59 (2): 134–7. 1983. PMC 1046157. PMID 6687557.
  9. Overfield TM, Brody JA (1966). "An epidemiologic study of molluscum contagiosum in Anchorage, Alaska". J. Pediatr. 69 (4): 640–2. PMID 5921341.
  10. Gottlieb SL, Myskowski PL (1994). "Molluscum contagiosum". Int. J. Dermatol. 33 (7): 453–61. PMID 7928025.
  11. Konya J, Thompson CH (1999). "Molluscum contagiosum virus: antibody responses in persons with clinical lesions and seroepidemiology in a representative Australian population". J. Infect. Dis. 179 (3): 701–4. doi:10.1086/314620. PMID 9952381.

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