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{{Tropical sprue}}
{{Tropical sprue}}
{{CMG}}; {{AE}}
{{CMG}}; {{AE}}  {{AKI}}


==Overview==
==Overview==
TS bears all the hallmarks of an infectious disease although the exact etiology remains largely unknown despite numerous efforts to identify the etiological agent.
The exact etiological agent responsible for causing [[tropical sprue]] is unknown, but different types of [[bacteria]] are identified in patients with [[tropical sprue]].


==Causes==
==Causes==
 
[[Small bowel bacterial overgrowth]] is thought to be the primary cause for [[tropical sprue]] but the exact cause of [[tropical sprue]] is still unknown. Tropical sprue occurs in regions where [[enteric]] infections are common and the most common [[bacteria]] isolated in patients with [[tropical sprue]] include:<ref name="pmid4178002">{{cite journal| author=Gorbach SL, Mitra R, Jacobs B, Banwell JG, Chatterjee BD, Mazumder DN| title=Bacterial contamination of the upper small bowel in tropical sprue. | journal=Lancet | year= 1969 | volume= 1 | issue= 7585 | pages= 74-7 | pmid=4178002 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=4178002  }} </ref><ref name="pmid773737">{{cite journal| author=Klipstein FA, Short HB, Engert RF, Jean L, Weaver GA| title=Contamination of the small intestine by enterotoxigenic coliform bacteria among the rural population of Haiti. | journal=Gastroenterology | year= 1976 | volume= 70 | issue= 6 | pages= 1035-41 | pmid=773737 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=773737  }} </ref><ref name="pmid4551005">{{cite journal| author=Bhat P, Shantakumari S, Rajan D, Mathan VI, Kapadia CR, Swarnabai C et al.| title=Bacterial flora of the gastrointestinal tract in southern Indian control subjects and patients with tropical sprue. | journal=Gastroenterology | year= 1972 | volume= 62 | issue= 1 | pages= 11-21 | pmid=4551005 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=4551005  }} </ref>
The cause of tropical sprue is not known. It has been suggested that it is caused by bacterial, viral, amoebal, or parasitic infection which affects residents of (or visitors to) the tropics. The resolution of symptoms after long-term antibiotic treatment with tetracycline or sulphamethoxazole/trimethoprim combined with vitamin supplementation suggests an infectious cause even though a causative micro-organism has never been demonstrated.<ref name="Walker2003">{{cite journal|last1=Walker|first1=Marjorie M|title=What is tropical sprue?|journal=Journal of Gastroenterology and Hepatology|volume=18|issue=8|year=2003|pages=887–890|issn=0815-9319|doi=10.1046/j.1440-1746.2003.03127.x}}</ref><ref name="Cook1984">{{cite journal|last1=Cook|first1=G.C.|title=AETIOLOGY AND PATHOGENESIS OF POSTINFECTIVE TROPICAL MALABSORPTION (TROPICAL SPRUE)|journal=The Lancet|volume=323|issue=8379|year=1984|pages=721–723|issn=01406736|doi=10.1016/S0140-6736(84)92231-1}}</ref>
*[[Escherichia coli]]
 
*[[Klebsiella pneumoniae]]
 
*[[Enterobacter]] cloace


==References==
==References==
{{Reflist|2}}
{{Reflist|2}}
[[Category:Gastroenterology]]


{{WS}}
{{WS}}
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[[Category:Emergency mdicine]]
[[Category:Disease]]
[[Category:Up-To-Date]]
[[Category:Infectious disease]]
[[Category:Gastroenterology]]

Latest revision as of 00:29, 30 July 2020

Tropical sprue Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aravind Kuchkuntla, M.B.B.S[2]

Overview

The exact etiological agent responsible for causing tropical sprue is unknown, but different types of bacteria are identified in patients with tropical sprue.

Causes

Small bowel bacterial overgrowth is thought to be the primary cause for tropical sprue but the exact cause of tropical sprue is still unknown. Tropical sprue occurs in regions where enteric infections are common and the most common bacteria isolated in patients with tropical sprue include:[1][2][3]

References

  1. Gorbach SL, Mitra R, Jacobs B, Banwell JG, Chatterjee BD, Mazumder DN (1969). "Bacterial contamination of the upper small bowel in tropical sprue". Lancet. 1 (7585): 74–7. PMID 4178002.
  2. Klipstein FA, Short HB, Engert RF, Jean L, Weaver GA (1976). "Contamination of the small intestine by enterotoxigenic coliform bacteria among the rural population of Haiti". Gastroenterology. 70 (6): 1035–41. PMID 773737.
  3. Bhat P, Shantakumari S, Rajan D, Mathan VI, Kapadia CR, Swarnabai C; et al. (1972). "Bacterial flora of the gastrointestinal tract in southern Indian control subjects and patients with tropical sprue". Gastroenterology. 62 (1): 11–21. PMID 4551005.

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