Fibroadenoma classification: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{Fibroadenoma}} | {{Fibroadenoma}} | ||
{{CMG}} {{AE}} {{HL}} | {{CMG}} {{AE}} {{IO}} {{HL}} | ||
==Overview== | ==Overview== | ||
Fibroadenoma may be classified according to microscopic histopathological analysis into four subtypes, which include juvenile fibroadenoma, complex fibroadenoma, giant fibroadenoma, myxoid fibroadenoma, and cellular fibroadenoma. | |||
==Classification== | ==Classification== | ||
* Fibroadenoma may be classified according to microscopic histopathological analysis into | * Fibroadenoma may be classified according to microscopic histopathological analysis into five subtypes, which include:<ref name="pmid24872735">{{cite journal| author=Cerrato F, Labow BI| title=Diagnosis and management of fibroadenomas in the adolescent breast. | journal=Semin Plast Surg | year= 2013 | volume= 27 | issue= 1 | pages= 23-5 | pmid=24872735 | doi=10.1055/s-0033-1343992 | pmc=3706050 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24872735 }} </ref> | ||
:* Juvenile fibroadenoma | :* Juvenile fibroadenoma | ||
:* Complex fibroadenoma | :* Complex fibroadenoma | ||
:* Giant fibroadenoma | |||
:* Myxoid fibroadenoma | :* Myxoid fibroadenoma | ||
:* Cellular fibroadenoma | :* Cellular fibroadenoma | ||
* The table below differentiates between the main subtypes of fibrodenoma according to microscopic histopathological analysis:<ref name="pmid24872735">{{cite journal| author=Cerrato F, Labow BI| title=Diagnosis and management of fibroadenomas in the adolescent breast. | journal=Semin Plast Surg | year= 2013 | volume= 27 | issue= 1 | pages= 23-5 | pmid=24872735 | doi=10.1055/s-0033-1343992 | pmc=3706050 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24872735 }} </ref><ref name="pmid29546008">{{cite journal| author=Giannos A, Stavrou S, Gkali C, Chra E, Marinopoulos S, Chalazonitis A et al.| title=A prepubertal giant juvenile fibroadenoma in a 12-year-old girl: Case report and brief literature review. | journal=Int J Surg Case Rep | year= 2017 | volume= 41 | issue= | pages= 427-430 | pmid=29546008 | doi=10.1016/j.ijscr.2017.11.026 | pmc=5702868 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29546008 }} </ref><ref name="pmid9754521">{{cite journal| author=Greenberg R, Skornick Y, Kaplan O| title=Management of breast fibroadenomas. | journal=J Gen Intern Med | year= 1998 | volume= 13 | issue= 9 | pages= 640-5 | pmid=9754521 | doi= | pmc=1497021 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9754521 }} </ref> | |||
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! style="background: #4479BA; width: 250px; color: #FFFFFF;"|'''Fibroadenoma Subtype''' | |||
! style="background: #4479BA; width: 600px; color: #FFFFFF;"|'''Description''' | |||
|- | |||
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''Juvenile fibroadenoma '''|| style="padding: 5px 5px; background: #F5F5F5;" | | |||
:* Commonly found in ages 10 to 18 years. | |||
:* Stromal and epithelial hyperplasia | |||
:* Tapering, thin micropapillae (gynecomastoid hyperplasia) | |||
:* Mitoses is absent | |||
:* Occurs mostly in African Americans | |||
:* Rapid growth | |||
:* Associated with skin ulcerations and prominent veins | |||
:* Referred to as a giant fibroadenoma when it is >5cm, >500g, or replaces more than 80% of the breast | |||
|- | |||
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''Complex fibroadenoma '''|| style="padding: 5px 5px; background: #F5F5F5;"| | |||
:* Excessive proliferation of epithelial cells | |||
:* Apocrine metaplasia | |||
:* Cysts > 3 mm | |||
:* Calcification | |||
:* Sclerosing adenosis | |||
|- | |||
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''Giant fibroadenoma ''' || style="padding: 5px 5px; background: #F5F5F5;"| | |||
:* >5cm in diameter | |||
:* High stromal cellularity | |||
:* Rapid growth | |||
:* Usually seen in pregnant or lactating women | |||
|- | |||
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''Myxoid fibroadenoma'''|| style="padding: 5px 5px; background: #F5F5F5;"| | |||
:* Myxoid stroma | |||
|- | |||
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''Cellular fibroadenoma '''|| style="padding: 5px 5px; background: #F5F5F5;" | | |||
:* Relatively high cellular component | |||
:* Increased mitotic rate | |||
:* Absence of calcification and sclerosing adenosis | |||
:* Sometimes referred to as juvenile fibroadenoma | |||
|} | |||
==References== | ==References== | ||
{{reflist| | {{reflist|1}} | ||
{{Soft tissue tumors and sarcomas}} | {{Soft tissue tumors and sarcomas}} | ||
{{WH}} | {{WH}} | ||
{{WS}} | {{WS}} | ||
[[Category:Breast]] | |||
[[Category:Up-To-Date]] | |||
[[Category:Oncology]] | |||
[[Category:Medicine]] |
Latest revision as of 21:45, 29 July 2020
Fibroadenoma Microchapters |
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Fibroadenoma classification On the Web |
American Roentgen Ray Society Images of Fibroadenoma classification |
Risk calculators and risk factors for Fibroadenoma classification |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Ifeoma Odukwe, M.D. [2] Haytham Allaham, M.D. [3]
Overview
Fibroadenoma may be classified according to microscopic histopathological analysis into four subtypes, which include juvenile fibroadenoma, complex fibroadenoma, giant fibroadenoma, myxoid fibroadenoma, and cellular fibroadenoma.
Classification
- Fibroadenoma may be classified according to microscopic histopathological analysis into five subtypes, which include:[1]
- Juvenile fibroadenoma
- Complex fibroadenoma
- Giant fibroadenoma
- Myxoid fibroadenoma
- Cellular fibroadenoma
- The table below differentiates between the main subtypes of fibrodenoma according to microscopic histopathological analysis:[1][2][3]
Fibroadenoma Subtype | Description |
---|---|
Juvenile fibroadenoma |
|
Complex fibroadenoma |
|
Giant fibroadenoma |
|
Myxoid fibroadenoma |
|
Cellular fibroadenoma |
|
References
- ↑ 1.0 1.1 Cerrato F, Labow BI (2013). "Diagnosis and management of fibroadenomas in the adolescent breast". Semin Plast Surg. 27 (1): 23–5. doi:10.1055/s-0033-1343992. PMC 3706050. PMID 24872735.
- ↑ Giannos A, Stavrou S, Gkali C, Chra E, Marinopoulos S, Chalazonitis A; et al. (2017). "A prepubertal giant juvenile fibroadenoma in a 12-year-old girl: Case report and brief literature review". Int J Surg Case Rep. 41: 427–430. doi:10.1016/j.ijscr.2017.11.026. PMC 5702868. PMID 29546008.
- ↑ Greenberg R, Skornick Y, Kaplan O (1998). "Management of breast fibroadenomas". J Gen Intern Med. 13 (9): 640–5. PMC 1497021. PMID 9754521.