Fosinopril use in specific populations: Difference between revisions

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#REDIRECT [[Fosinopril#Use in Specific Populations]]
{{Fosinopril}}
{{CMG}}; {{AE}} {{AM}}
 
===Nursing Mothers===
 
Ingestion of 20 mg daily for three days resulted in detectable levels of fosinoprilat in breast milk. Fosinopril Na tablets should not be administered to nursing mothers.
 
===Geriatric Use===
 
Clinical studies of fosinopril sodium tablets did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects. Other reported clinical experience has not identified differences in responses between the elderly and younger patients. In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy.
 
===Pediatric Use===
 
Neonates with a history of in utero exposure to fosinopril sodium tablets
 
If [[oliguria]] or [[hypotension]] occurs, direct attention toward support of blood pressure and renal perfusion. Exchange transfusions or dialysis may be required as a means of reversing hypotension and/or substituting for disordered renal function. Removal of fosinopril, which crosses the [[placenta]], from the [[neonatal circulation]] is not significantly accelerated by these means.
 
The antihypertensive effects of fosinopril have been evaluated in a double-blind study in pediatric patients 6 to 16 years of age. The pharmacokinetics of fosinopril have been evaluated in pediatric patients 6 to 16 years of age. Fosinopril was generally well tolerated and adverse effects were similar to those described in adults.<ref name="dailymed.nlm.nih.gov">{{Cite web  | last =  | first =  | title = FOSINOPRIL NA (FOSINOPRIL SODIUM) TABLET [APOTEX CORP.] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=eaa753e8-9fda-af0b-9d54-bdf0d1674832 | publisher =  | date =  | accessdate = }}</ref>
 
==References==
{{Reflist}}
 
{{FDA}}
 
[[Category:Cardiovascular Drugs]]
[[Category:Drugs]]

Latest revision as of 19:49, 21 July 2014