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Revision as of 19:21, 4 September 2012


Macrophage stimulating 1 (hepatocyte growth factor-like)
File:PBB Protein MST1 image.jpg
PDB rendering based on 2asu.
Available structures
PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB
Identifiers
Symbols MST1 ; D3F15S2; DNF15S2; MSP; HGFL; NF15S2
External IDs Template:OMIM5 Template:MGI HomoloGene7360
RNA expression pattern
File:PBB GE MST1 205614 x at tn.png
File:PBB GE MST1 213380 x at tn.png
File:PBB GE MST1 216320 x at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species Human Mouse
Entrez n/a n/a
Ensembl n/a n/a
UniProt n/a n/a
RefSeq (mRNA) n/a n/a
RefSeq (protein) n/a n/a
Location (UCSC) n/a n/a
PubMed search n/a n/a

Macrophage stimulating 1 (hepatocyte growth factor-like), also known as MST1, is a human gene.[1]


References

  1. "Entrez Gene: MST1 macrophage stimulating 1 (hepatocyte growth factor-like)".

Further reading

  • Han S, Stuart LA, Degen SJ (1991). "Characterization of the DNF15S2 locus on human chromosome 3: identification of a gene coding for four kringle domains with homology to hepatocyte growth factor". Biochemistry. 30 (40): 9768–80. PMID 1655021.
  • Skeel A, Yoshimura T, Showalter SD; et al. (1991). "Macrophage stimulating protein: purification, partial amino acid sequence, and cellular activity". J. Exp. Med. 173 (5): 1227–34. PMID 1827141.
  • Gerber MJ, Drabkin HA, Firnhaber C; et al. (1988). "Regional localization of chromosome 3-specific DNA fragments by using a hybrid cell deletion mapping panel". Am. J. Hum. Genet. 43 (4): 442–51. PMID 2902784.
  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. PMID 8125298.
  • Yoshimura T, Yuhki N, Wang MH; et al. (1993). "Cloning, sequencing, and expression of human macrophage stimulating protein (MSP, MST1) confirms MSP as a member of the family of kringle proteins and locates the MSP gene on chromosome 3". J. Biol. Chem. 268 (21): 15461–8. PMID 8393443.
  • Waltz SE, Gould FK, Air EL; et al. (1996). "Hepatocyte nuclear factor-4 is responsible for the liver-specific expression of the gene coding for hepatocyte growth factor-like protein". J. Biol. Chem. 271 (15): 9024–32. PMID 8621550.
  • Creasy CL, Ambrose DM, Chernoff J (1996). "The Ste20-like protein kinase, Mst1, dimerizes and contains an inhibitory domain". J. Biol. Chem. 271 (35): 21049–53. PMID 8702870.
  • Sakamoto O, Iwama A, Amitani R; et al. (1997). "Role of macrophage-stimulating protein and its receptor, RON tyrosine kinase, in ciliary motility". J. Clin. Invest. 99 (4): 701–9. PMID 9045873.
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K; et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. PMID 9373149.
  • Yoshikawa W, Hara H, Takehara T; et al. (1999). "Characterization of free alpha- and beta-chains of recombinant macrophage-stimulating protein". Arch. Biochem. Biophys. 363 (2): 356–60. doi:10.1006/abbi.1998.1090. PMID 10068459.
  • Degen SJ, McDowell SA, Waltz SE; et al. (2000). "Structure of the human D1F15S1A locus: a chromosome 1 locus with 97% identity to the chromosome 3 gene coding for hepatocyte growth factor-like protein". DNA Seq. 8 (6): 409–13. PMID 10728827.
  • Skeel A, Leonard EJ (2001). "alpha 1-Antichymotrypsin is the human plasma inhibitor of macrophage ectoenzymes that cleave pro-macrophage stimulating protein". J. Biol. Chem. 276 (24): 21932–7. doi:10.1074/jbc.M100652200. PMID 11274154.
  • Rampino T, Collesi C, Gregorini M; et al. (2002). "Macrophage-stimulating protein is produced by tubular cells and activates mesangial cells". J. Am. Soc. Nephrol. 13 (3): 649–57. PMID 11856768.
  • Zhou YQ, Chen YQ, Fisher JH, Wang MH (2002). "Activation of the RON receptor tyrosine kinase by macrophage-stimulating protein inhibits inducible cyclooxygenase-2 expression in murine macrophages". J. Biol. Chem. 277 (41): 38104–10. doi:10.1074/jbc.M206167200. PMID 12177064.
  • Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
  • Santoro MM, Gaudino G, Marchisio PC (2003). "The MSP receptor regulates alpha6beta4 and alpha3beta1 integrins via 14-3-3 proteins in keratinocyte migration". Dev. Cell. 5 (2): 257–71. PMID 12919677.
  • Angeloni D, Danilkovitch-Miagkova A, Miagkov A; et al. (2004). "The soluble sema domain of the RON receptor inhibits macrophage-stimulating protein-induced receptor activation". J. Biol. Chem. 279 (5): 3726–32. doi:10.1074/jbc.M309342200. PMID 14597639.
  • Matsuzaki S, Canis M, Pouly JL; et al. (2005). "The macrophage stimulating protein/RON system: a potential novel target for prevention and treatment of endometriosis". Mol. Hum. Reprod. 11 (5): 345–9. doi:10.1093/molehr/gah162. PMID 15764806.
  • Zalcenstein A, Weisz L, Stambolsky P; et al. (2006). "Repression of the MSP/MST-1 gene contributes to the antiapoptotic gain of function of mutant p53". Oncogene. 25 (3): 359–69. doi:10.1038/sj.onc.1209061. PMID 16170349.
  • Liu T, Qian WJ, Gritsenko MA; et al. (2006). "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry". J. Proteome Res. 4 (6): 2070–80. doi:10.1021/pr0502065. PMID 16335952.

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