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Revision as of 17:58, 4 September 2012


Hemoglobin, beta
PDB rendering based on 1a00.
Available structures
PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB
Identifiers
Symbols HBB ; CD113t-C; HBD
External IDs Template:OMIM5 Template:MGI HomoloGene68066
Orthologs
Template:GNF Ortholog box
Species Human Mouse
Entrez n/a n/a
Ensembl n/a n/a
UniProt n/a n/a
RefSeq (mRNA) n/a n/a
RefSeq (protein) n/a n/a
Location (UCSC) n/a n/a
PubMed search n/a n/a

Beta globin (HBB, β-globin) is a protein that, along with alpha globin (HBA), makes up the most common form of hemoglobin in adult humans. The gene is located in the β-globin locus. Mutant beta globin is responsible for the sickling of red blood cells seen in sickle cell anemia. Expression of beta globin and the neighboring globins in the β-globin locus is controlled by single locus control region (LCR).[1]


See also

Human β-globin locus


References

  1. Levings & Bungert (2002)


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