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Revision as of 14:00, 4 September 2012


Rho GDP dissociation inhibitor (GDI) beta
PDB rendering based on 1ds6.
Available structures
PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB
Identifiers
Symbols ARHGDIB ; D4; GDIA2; GDID4; LYGDI; Ly-GDI; RAP1GN1
External IDs Template:OMIM5 Template:MGI HomoloGene20318
RNA expression pattern
More reference expression data
Orthologs
Template:GNF Ortholog box
Species Human Mouse
Entrez n/a n/a
Ensembl n/a n/a
UniProt n/a n/a
RefSeq (mRNA) n/a n/a
RefSeq (protein) n/a n/a
Location (UCSC) n/a n/a
PubMed search n/a n/a

Rho GDP dissociation inhibitor (GDI) beta, also known as ARHGDIB, is a human gene.[1]


References

  1. "Entrez Gene: ARHGDIB Rho GDP dissociation inhibitor (GDI) beta".

Further reading

  • Aebersold R, Leavitt J (1990). "Sequence analysis of proteins separated by polyacrylamide gel electrophoresis: towards an integrated protein database". Electrophoresis. 11 (7): 517–27. doi:10.1002/elps.1150110702. PMID 2226408.
  • Shisheva A, Südhof TC, Czech MP (1994). "Cloning, characterization, and expression of a novel GDP dissociation inhibitor isoform from skeletal muscle". Mol. Cell. Biol. 14 (5): 3459–68. PMID 7513052.
  • Adra CN, Kobayashi H, Rowley JD, Lim B (1995). "Assignment of the human GDID4 gene, a GDP/GTP-exchange regulator, to chromosome 12p12.3". Genomics. 24 (1): 188–90. doi:10.1006/geno.1994.1601. PMID 7896279.
  • Leffers H, Nielsen MS, Andersen AH; et al. (1994). "Identification of two human Rho GDP dissociation inhibitor proteins whose overexpression leads to disruption of the actin cytoskeleton". Exp. Cell Res. 209 (2): 165–74. doi:10.1006/excr.1993.1298. PMID 8262133.
  • Scherle P, Behrens T, Staudt LM (1993). "Ly-GDI, a GDP-dissociation inhibitor of the RhoA GTP-binding protein, is expressed preferentially in lymphocytes". Proc. Natl. Acad. Sci. U.S.A. 90 (16): 7568–72. PMID 8356058.
  • Lelias JM, Adra CN, Wulf GM; et al. (1993). "cDNA cloning of a human mRNA preferentially expressed in hematopoietic cells and with homology to a GDP-dissociation inhibitor for the rho GTP-binding proteins". Proc. Natl. Acad. Sci. U.S.A. 90 (4): 1479–83. PMID 8434008.
  • Adra CN, Manor D, Ko JL; et al. (1997). "RhoGDIgamma: a GDP-dissociation inhibitor for Rho proteins with preferential expression in brain and pancreas". Proc. Natl. Acad. Sci. U.S.A. 94 (9): 4279–84. PMID 9113980.
  • Takahashi K, Sasaki T, Mammoto A; et al. (1997). "Direct interaction of the Rho GDP dissociation inhibitor with ezrin/radixin/moesin initiates the activation of the Rho small G protein". J. Biol. Chem. 272 (37): 23371–5. PMID 9287351.
  • Gorvel JP, Chang TC, Boretto J; et al. (1998). "Differential properties of D4/LyGDI versus RhoGDI: phosphorylation and rho GTPase selectivity". FEBS Lett. 422 (2): 269–73. PMID 9490022.
  • Illenberger D, Schwald F, Pimmer D; et al. (1999). "Stimulation of phospholipase C-beta2 by the Rho GTPases Cdc42Hs and Rac1". EMBO J. 17 (21): 6241–9. doi:10.1093/emboj/17.21.6241. PMID 9799233.
  • Scheffzek K, Stephan I, Jensen ON; et al. (2000). "The Rac-RhoGDI complex and the structural basis for the regulation of Rho proteins by RhoGDI". Nat. Struct. Biol. 7 (2): 122–6. doi:10.1038/72392. PMID 10655614.
  • Groysman M, Russek CS, Katzav S (2000). "Vav, a GDP/GTP nucleotide exchange factor, interacts with GDIs, proteins that inhibit GDP/GTP dissociation". FEBS Lett. 467 (1): 75–80. PMID 10664460.
  • Kasper B, Tidow N, Grothues D, Welte K (2000). "Differential expression and regulation of GTPases (RhoA and Rac2) and GDIs (LyGDI and RhoGDI) in neutrophils from patients with severe congenital neutropenia". Blood. 95 (9): 2947–53. PMID 10779444.
  • Fauré J, Dagher MC (2001). "Interactions between Rho GTPases and Rho GDP dissociation inhibitor (Rho-GDI)". Biochimie. 83 (5): 409–14. PMID 11368848.
  • Li X, Bu X, Lu B; et al. (2002). "The hematopoiesis-specific GTP-binding protein RhoH is GTPase deficient and modulates activities of other Rho GTPases by an inhibitory function". Mol. Cell. Biol. 22 (4): 1158–71. PMID 11809807.
  • Kwon KB, Park EK, Ryu DG, Park BH (2003). "D4-GDI is cleaved by caspase-3 during daunorubicin-induced apoptosis in HL-60 cells". Exp. Mol. Med. 34 (1): 32–7. PMID 11989976.
  • Thiede B, Siejak F, Dimmler C, Rudel T (2003). "Prediction of translocation and cleavage of heterogeneous ribonuclear proteins and Rho guanine nucleotide dissociation inhibitor 2 during apoptosis by subcellular proteome analysis". Proteomics. 2 (8): 996–1006. doi:10.1002/1615-9861(200208)2:8<996::AID-PROT996>3.0.CO;2-3. PMID 12203895.
  • Groysman M, Hornstein I, Alcover A, Katzav S (2003). "Vav1 and Ly-GDI two regulators of Rho GTPases, function cooperatively as signal transducers in T cell antigen receptor-induced pathways". J. Biol. Chem. 277 (51): 50121–30. doi:10.1074/jbc.M204299200. PMID 12386169.
  • Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.

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