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| __NOTOC__ | | __NOTOC__ |
| {{Brain tumor}} | | {{Brain tumor}} |
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| | {{CMG}} |
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| | ==Overview== |
| | The cause of primary brain tumors is unknown.<ref name="nlmnihgov">National Library of Medicine.http://www.nlm.nih.gov/medlineplus/cancer.html</ref> |
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| ==Cause== | | ==Cause== |
| Epidemiological studies are required to determine risk factors.<ref>{{cite journal|last1=Krishnatreya|first1=M|last2=Kataki|first2=AC|last3=Sharma|first3=JD|last4=Bhattacharyya|first4=M|last5=Nandy|first5=P|last6=Hazarika|first6=M|title=Brief descriptive epidemiology of primary malignant brain tumors from North-East India.|journal=Asian Pacific journal of cancer prevention : APJCP|date=2014|volume=15|issue=22|pages=9871–3|pmid=25520120|doi=10.7314/apjcp.2014.15.22.9871}}</ref> Aside from exposure to [[vinyl chloride]] or [[ionizing radiation]], there are no known environmental factors associated with brain tumors. Mutations and deletions of so-called [[tumor suppressor gene]]s, such as [[P53]], are thought to be the cause of some forms of brain tumor.<ref>{{cite book | author = Kleihues P, Ohgaki H, Eibl RH, Reichel MB, Mariani L, Gehring M, Petersen I, Höll T, von Deimling A, Wiestler OD, Schwab M | chapter = Type and frequency of p53 mutations in tumors of the nervous system and its coverings | title = Molecular Neuro-oncology and Its Impact on the Clinical Management of Brain Tumors | pages = 25–31 | year = 1994 | publisher = Springer |isbn=3540573518 |series=Recent results in cancer research |volume=135}}</ref> Inherited conditions, such as Von Hippel–Lindau disease, [[multiple endocrine neoplasia]], and [[Neurofibromatosis|neurofibromatosis type 2]] carry a high risk for the development of brain tumors.
| | The cause of primary brain tumors is unknown.<ref name="nlmnihgov">National Library of Medicine.http://www.nlm.nih.gov/medlineplus/cancer.html</ref> |
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| Although studies have not shown any link between [[Mobile phone radiation and health|cell phone or mobile phone radiation]] and the occurrence of brain tumors,<ref>{{cite journal | author = Frei P, Poulsen AH, Johansen C, Olsen JH, Steding-Jessen M, Schüz J | title = Use of mobile phones and risk of brain tumours: update of Danish cohort study. | journal = BMJ (Clinical research ed.) | volume = 343 | pages = d6387 | date = 19 October 2011 | pmid = 22016439 | pmc = 3197791 | doi = 10.1136/bmj.d6387 }}</ref> the [[World Health Organization]] has classified mobile phone radiation on the [[International Agency for Research on Cancer|IARC]] scale into [[List of IARC Group 2B carcinogens|Group 2B]] – possibly carcinogenic.<ref name="WHO_IARC_110531">{{cite press release|url= http://www.iarc.fr/en/media-centre/pr/2011/pdfs/pr208_E.pdf |format= PDF|title= IARC classifies radiofrequency electromagnetic fields as possibly carcinogenic to humans|work= [[World Health Organization]] press release N° 208|publisher= [[International Agency for Research on Cancer]]|date= 31 May 2011|accessdate= 2 June 2011}}</ref>
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| ==References== | | ==References== |
| {{Reflist|2}} | | {{Reflist|2}} |
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| | {{WH}} |
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| [[Category:Needs content]] | | [[Category:Needs content]] |
| [[Category:Primary care]]
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| [[Category:Disease]] | | [[Category:Disease]] |
| [[Category:Brain]] | | [[Category:Brain]] |
| [[Category:Neurology]] | | [[Category:Neurology]] |
| | | [[Category:Up-To-Date]] |
| {{WH}}
| | [[Category:Oncology]] |
| {{WS}}
| | [[Category:Medicine]] |
| | [[Category:Neurosurgery]] |