African trypanosomiasis classification: Difference between revisions

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{{African trypanosomiasis}}
{{African trypanosomiasis}}
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==Overview==
[[African trypanosomiasis]] can be classified based upon the [[pathogen]] and geographic location into two types, [[Trypanosomiasis, east-African|East African trypanosomiasis]] and [[Trypanosomiasis, west African|West African trypanosomiasis]].
 
==Classification==
[[African trypanosomiasis]] can be classified based upon the [[pathogen]] and geographic location into the following types:<ref name="pmid16308383">{{cite journal |vauthors=Picozzi K, Fèvre EM, Odiit M, Carrington M, Eisler MC, Maudlin I, Welburn SC |title=Sleeping sickness in Uganda: a thin line between two fatal diseases |journal=BMJ |volume=331 |issue=7527 |pages=1238–41 |year=2005 |pmid=16308383 |pmc=1289320 |doi=10.1136/bmj.331.7527.1238 |url=}}</ref>
{| class="wikitable"
! rowspan="2" |Disease
! rowspan="2" |Pathogen
! rowspan="2" |Geographic
distribution
! rowspan="2" |Progression
! colspan="2" |Symptoms
|-
|First stage
|Second stage
|-
|East African sleeping sickness
|[[Trypanosoma brucei rhodesiense|''Trypanosoma brucei'' rhodesiense]]  
|East and Southeast Africa
|Rapid
(1-2 weeks)
|
* A large sore ([[chancre]]) will develop at the site of the [[tsetse fly]] bite
* [[Fever]]
* [[Headache]]
* [[Myalgia|Myalgias]]
* [[Arthralgias]]
* [[Lymphadenopathy]]
|
* [[Mental Disorders|Mental deterioration]] and other [[Neurological disorder|neurologic problems]]
* Death ensues usually within months
|-
|West African sleeping sickness
|[[Trypanosoma brucei gambiense|''Trypanosoma brucei'' gambiense]]
|West and Central Africa
|Slow
(1-2 years)
|
* Intermittent [[fevers]]
* [[Headaches]]
* [[Myalgias]]
* [[Arthralgias]]
* [[Malaise]]
* [[Itching]] of the [[skin]]
* [[Lymphadenopathy]]
* [[Weight loss]]
|
* Personality changes
* [[Daytime sleepiness]] with night time sleep disturbance
* Progressive [[confusion]]
* Partial [[paralysis]] or problems with balance or walking may occur
* [[Hormonal|Hormona]]<nowiki/>l imbalances
* The course of untreated [[infection]] rarely lasts longer than 6-7 years and more often kills in about 3 years.
|}
 
==References==
==References==
{{Reflist|2}}
{{Reflist|2}}
[[Category:Needs content]]
 
[[Category:Disease]]
[[Category:Up-To-Date]]
[[Category:Dermatology]]
[[Category:Neurology]]
[[Category:Emergency medicine]]
[[Category:Infectious disease]]

Latest revision as of 20:19, 29 July 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aditya Ganti M.B.B.S. [2]

Overview

African trypanosomiasis can be classified based upon the pathogen and geographic location into two types, East African trypanosomiasis and West African trypanosomiasis.

Classification

African trypanosomiasis can be classified based upon the pathogen and geographic location into the following types:[1]

Disease Pathogen Geographic

distribution

Progression Symptoms
First stage Second stage
East African sleeping sickness Trypanosoma brucei rhodesiense East and Southeast Africa Rapid

(1-2 weeks)

West African sleeping sickness Trypanosoma brucei gambiense West and Central Africa Slow

(1-2 years)

  • Personality changes
  • Daytime sleepiness with night time sleep disturbance
  • Progressive confusion
  • Partial paralysis or problems with balance or walking may occur
  • Hormonal imbalances
  • The course of untreated infection rarely lasts longer than 6-7 years and more often kills in about 3 years.

References

  1. Picozzi K, Fèvre EM, Odiit M, Carrington M, Eisler MC, Maudlin I, Welburn SC (2005). "Sleeping sickness in Uganda: a thin line between two fatal diseases". BMJ. 331 (7527): 1238–41. doi:10.1136/bmj.331.7527.1238. PMC 1289320. PMID 16308383.