|
|
| Line 1: |
Line 1: |
| {{Infobox_Disease
| | #redirect:[[Non-bacterial thrombotic endocarditis]] |
| | Name = {{PAGENAME}}
| |
| | Image =
| |
| | Caption =
| |
| | DiseasesDB = 29250
| |
| | ICD10 =
| |
| | ICD9 =
| |
| | ICDO =
| |
| | OMIM =
| |
| | MedlinePlus =
| |
| | eMedicineSubj =
| |
| | eMedicineTopic =
| |
| | MeshID =
| |
| }}
| |
| {{SI}}
| |
| | |
| | |
| '''Marantic endocarditis,''' also known as '''non-bacterial thrombotic endocarditis''' (NBTE), is the deposition of small [[sterile]] [[vegetation (pathology)|vegetation]]s on [[heart valve|valve]] leaflets.
| |
| | |
| The previous term for nonbacterial thrombotic endocarditis (NBTE) was marantic endocarditis, from the Greek marantikos, meaning “wasting away.”<ref name="titleeMedicine - Neurological Sequelae of Infectious Endocarditis : Article by Milind J Kothari">{{cite web |url=http://www.emedicine.com/neuro/topic264.htm |title=eMedicine - Neurological Sequelae of Infectious Endocarditis : Article by Milind J Kothari |accessdate=2008-03-23 |format= |work=}}</ref>
| |
| | |
| ==Risk factors==
| |
| Marantic vegetations are often associated with previous [[rheumatic fever]].
| |
| | |
| Other risk factors include:
| |
| * [[hypercoagulable state]]s,
| |
| * mucin-producing [[adenocarcinoma]]s,
| |
| * [[lupus]] and
| |
| * [[Physical trauma|trauma]] (e.g., [[catheters]]).
| |
| | |
| ==Valve predilection==
| |
| The disease affects the valves with the following predilection:
| |
| | |
| [[mitral valve]] > [[aortic valve]] > [[tricuspid valve]] > [[pulmonary valve]].
| |
| | |
| ==Presentation==
| |
| Grossly, vegetations form along lines of valve closure and are generally symmetric with a smooth or [[verruca|verrucoid]] (warty) texture. [[histology|Histologically]], lesions are composed of [[fibrin]]<ref>{{DorlandsDict|nine/000952354|nonbacterial thrombotic endocarditis}}</ref> (eosinophilic) and [[platelet]]s but, unlike [[bacteria]]l etiologies, contain little evidence of [[Polymorphonuclear leukocytes|PMNs]], [[microorganism]]s or [[inflammation]].
| |
| | |
| ==Diagnosis==
| |
| Due to the non-invasive nature of NBTE, clinical examination may or may not reveal a new [[heart murmurs|murmur]].
| |
| | |
| It is imperative to take the [[blood pressure]] in both arms.
| |
| | |
| ==References==
| |
| {{reflist|2}}
| |
| {{Heart diseases}}
| |
| | |
| | |
| {{WH}}
| |
| {{WS}}
| |
| | |
| [[Category:Disease]]
| |
| [[Category:Cardiology]]
| |