KIFC1: Difference between revisions
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* {{cite journal | vauthors = Miki H, Setou M, Kaneshiro K, Hirokawa N | title = All kinesin superfamily protein, KIF, genes in mouse and human | journal = Proc. Natl. Acad. Sci. U.S.A. | volume = 98 | issue = 13 | pages = 7004–11 | year = 2001 | pmid = 11416179 | pmc = 34614 | doi = 10.1073/pnas.111145398 }} | * {{cite journal | vauthors = Miki H, Setou M, Kaneshiro K, Hirokawa N | title = All kinesin superfamily protein, KIF, genes in mouse and human | journal = Proc. Natl. Acad. Sci. U.S.A. | volume = 98 | issue = 13 | pages = 7004–11 | year = 2001 | pmid = 11416179 | pmc = 34614 | doi = 10.1073/pnas.111145398 }} | ||
* {{cite journal | vauthors = Janitz K, Wild A, Beck S, Savasta S, Beluffi G, Ziegler A, Volz A | title = Genomic organization of the HSET locus and the possible association of HLA-linked genes with immotile cilia syndrome (ICS) | journal = Immunogenetics | volume = 49 | issue = 7–8 | pages = 644–52 | year = 1999 | pmid = 10369922 | doi = 10.1007/s002510050660 }} | * {{cite journal | vauthors = Janitz K, Wild A, Beck S, Savasta S, Beluffi G, Ziegler A, Volz A | title = Genomic organization of the HSET locus and the possible association of HLA-linked genes with immotile cilia syndrome (ICS) | journal = Immunogenetics | volume = 49 | issue = 7–8 | pages = 644–52 | year = 1999 | pmid = 10369922 | doi = 10.1007/s002510050660 }} | ||
* {{cite journal | vauthors = Neef R, Preisinger C, Sutcliffe J, Kopajtich R, Nigg EA, Mayer TU, Barr FA | title = Phosphorylation of mitotic kinesin-like protein 2 by polo-like kinase 1 is required for cytokinesis | journal = J. Cell Biol. | volume = 162 | issue = 5 | pages = 863–75 | year = 2003 | pmid = 12939256 | pmc = 2172827 | doi = 10.1083/jcb.200306009 }} | * {{cite journal | vauthors = Neef R, Preisinger C, Sutcliffe J, Kopajtich R, Nigg EA, Mayer TU, Barr FA | title = Phosphorylation of mitotic kinesin-like protein 2 by polo-like kinase 1 is required for cytokinesis | journal = J. Cell Biol. | volume = 162 | issue = 5 | pages = 863–75 | year = 2003 | pmid = 12939256 | pmc = 2172827 | doi = 10.1083/jcb.200306009 | url = https://kops.uni-konstanz.de/bitstream/123456789/14050/2/Mayer%20etal.pdf }} | ||
* {{cite journal | vauthors = Gruneberg U, Neef R, Honda R, Nigg EA, Barr FA | title = Relocation of Aurora B from centromeres to the central spindle at the metaphase to anaphase transition requires MKlp2 | journal = J. Cell Biol. | volume = 166 | issue = 2 | pages = 167–72 | year = 2004 | pmid = 15263015 | pmc = 2172317 | doi = 10.1083/jcb.200403084 }} | * {{cite journal | vauthors = Gruneberg U, Neef R, Honda R, Nigg EA, Barr FA | title = Relocation of Aurora B from centromeres to the central spindle at the metaphase to anaphase transition requires MKlp2 | journal = J. Cell Biol. | volume = 166 | issue = 2 | pages = 167–72 | year = 2004 | pmid = 15263015 | pmc = 2172317 | doi = 10.1083/jcb.200403084 }} | ||
* {{cite journal | vauthors = Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M | title = Global, in vivo, and site-specific phosphorylation dynamics in signaling networks | journal = Cell | volume = 127 | issue = 3 | pages = 635–48 | year = 2006 | pmid = 17081983 | doi = 10.1016/j.cell.2006.09.026 }} | * {{cite journal | vauthors = Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M | title = Global, in vivo, and site-specific phosphorylation dynamics in signaling networks | journal = Cell | volume = 127 | issue = 3 | pages = 635–48 | year = 2006 | pmid = 17081983 | doi = 10.1016/j.cell.2006.09.026 }} | ||
Latest revision as of 15:37, 4 November 2018
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| External IDs | GeneCards: [1] | ||||||
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| Species | Human | Mouse | |||||
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| Location (UCSC) | n/a | n/a | |||||
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Kinesin-like protein KIFC1 is a protein that in humans is encoded by the KIFC1 gene.[1][2]
Function
The protein KifC1 is a member of kinesin-14 family. KifC1 consists of C-terminal motor domain, superhelical stalk and N-terminal tail domain. Tail and motor domains contain microtubule-binding sites. This kinesin moves towards the minus-end of microtubule and has an ability to slide or crosslink microtubules. KifC1 functions during mitotic spindle formation.
References
- ↑ Ando A, Kikuti YY, Kawata H, Okamoto N, Imai T, Eki T, Yokoyama K, Soeda E, Ikemura T, Abe K (Feb 1994). "Cloning of a new kinesin-related gene located at the centromeric end of the human MHC region". Immunogenetics. 39 (3): 194–200. doi:10.1007/bf00241260. PMID 8276466.
- ↑ "Entrez Gene: KIFC1 kinesin family member C1".
Further reading
- Miki H, Setou M, Kaneshiro K, Hirokawa N (2001). "All kinesin superfamily protein, KIF, genes in mouse and human". Proc. Natl. Acad. Sci. U.S.A. 98 (13): 7004–11. doi:10.1073/pnas.111145398. PMC 34614. PMID 11416179.
- Janitz K, Wild A, Beck S, Savasta S, Beluffi G, Ziegler A, Volz A (1999). "Genomic organization of the HSET locus and the possible association of HLA-linked genes with immotile cilia syndrome (ICS)". Immunogenetics. 49 (7–8): 644–52. doi:10.1007/s002510050660. PMID 10369922.
- Neef R, Preisinger C, Sutcliffe J, Kopajtich R, Nigg EA, Mayer TU, Barr FA (2003). "Phosphorylation of mitotic kinesin-like protein 2 by polo-like kinase 1 is required for cytokinesis" (PDF). J. Cell Biol. 162 (5): 863–75. doi:10.1083/jcb.200306009. PMC 2172827. PMID 12939256.
- Gruneberg U, Neef R, Honda R, Nigg EA, Barr FA (2004). "Relocation of Aurora B from centromeres to the central spindle at the metaphase to anaphase transition requires MKlp2". J. Cell Biol. 166 (2): 167–72. doi:10.1083/jcb.200403084. PMC 2172317. PMID 15263015.
- Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
- Al-Bassam J, Roger B, Halpain S, Milligan RA (2007). "Analysis of the weak interactions of ADP-Unc104 and ADP-kinesin with microtubules and their inhibition by MAP2c". Cell Motil. Cytoskeleton. 64 (5): 377–89. doi:10.1002/cm.20190. PMID 17326138.
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