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{{Infobox_gene}}
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'''Integrin beta-1-binding protein 1''' is a [[protein]] that in humans is encoded by the ''ITGB1BP1'' [[gene]].<ref name="pmid11854171">{{cite journal |vauthors=Zawistowski JS, Serebriiskii IG, Lee MF, Golemis EA, Marchuk DA | title = KRIT1 association with the integrin-binding protein ICAP-1: a new direction in the elucidation of cerebral cavernous malformations (CCM1) pathogenesis | journal = Hum Mol Genet | volume = 11 | issue = 4 | pages = 389–96 |date=March 2002 | pmid = 11854171 | pmc =  | doi =10.1093/hmg/11.4.389 }}</ref><ref name="pmid9281591">{{cite journal |vauthors=Chang DD, Wong C, Smith H, Liu J | title = ICAP-1, a novel beta1 integrin cytoplasmic domain-associated protein, binds to a conserved and functionally important NPXY sequence motif of beta1 integrin | journal = J Cell Biol | volume = 138 | issue = 5 | pages = 1149–57 |date=October 1997 | pmid = 9281591 | pmc = 2136751 | doi =10.1083/jcb.138.5.1149 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: ITGB1BP1 integrin beta 1 binding protein 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9270| accessdate = }}</ref>
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<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Integrin beta 1 binding protein 1
| HGNCid = 23927
| Symbol = ITGB1BP1
| AltSymbols =; DKFZp686K08158; ICAP-1A; ICAP-1B; ICAP1; ICAP1A; ICAP1B
| OMIM = 607153
| ECnumber =
| Homologene = 3496
| MGIid = 1306802
  | GeneAtlas_image1 = PBB_GE_ITGB1BP1_203337_x_at_tn.png
| GeneAtlas_image2 = PBB_GE_ITGB1BP1_203336_s_at_tn.png
  | Function = {{GNF_GO|id=GO:0008022 |text = protein C-terminus binding}}  
| Component = {{GNF_GO|id=GO:0016020 |text = membrane}}
| Process = {{GNF_GO|id=GO:0007155 |text = cell adhesion}} {{GNF_GO|id=GO:0007160 |text = cell-matrix adhesion}} {{GNF_GO|id=GO:0007243 |text = protein kinase cascade}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 9270
    | Hs_Ensembl = ENSG00000119185
    | Hs_RefseqProtein = NP_004754
    | Hs_RefseqmRNA = NM_004763
    | Hs_GenLoc_db =
    | Hs_GenLoc_chr = 2
    | Hs_GenLoc_start = 9463264
    | Hs_GenLoc_end = 9481127
    | Hs_Uniprot = O14713
    | Mm_EntrezGene = 16413
    | Mm_Ensembl = ENSMUSG00000062352
    | Mm_RefseqmRNA = NM_008403
    | Mm_RefseqProtein = NP_032429
    | Mm_GenLoc_db =   
    | Mm_GenLoc_chr = 12
    | Mm_GenLoc_start = 21513910
    | Mm_GenLoc_end = 21532727
    | Mm_Uniprot = Q3UGH2
  }}
}}
'''Integrin beta 1 binding protein 1''', also known as '''ITGB1BP1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: ITGB1BP1 integrin beta 1 binding protein 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9270| accessdate = }}</ref>


<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
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{{PBB_Summary
{{PBB_Summary
| section_title =  
| section_title =  
| summary_text = The cytoplasmic domains of integrins are essential for cell adhesion. The protein encoded by this gene binds to the beta1 integrin cytoplasmic domain. The interaction between this protein and beta1 integrin is highly specific. Two isoforms of this protein are derived from alternatively spliced transcripts. The shorter form of this protein does not interact with the beta1 integrin cytoplasmic domain. The longer form is a phosphoprotein and the extent of its phosphorylation is regulated by the cell-matrix interaction, suggesting an important role of this protein during integrin-dependent cell adhesion.<ref name="entrez">{{cite web | title = Entrez Gene: ITGB1BP1 integrin beta 1 binding protein 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9270| accessdate = }}</ref>
| summary_text = The cytoplasmic domains of integrins are essential for cell adhesion. The protein encoded by this gene binds to the beta1 integrin cytoplasmic domain. The interaction between this protein and beta1 integrin is highly specific. Two isoforms of this protein are derived from alternatively spliced transcripts. The shorter form of this protein does not interact with the beta1 integrin cytoplasmic domain. The longer form is a phosphoprotein and the extent of its phosphorylation is regulated by the cell-matrix interaction, suggesting an important role of this protein during integrin-dependent cell adhesion.<ref name="entrez" />
}}
}}
==Interactions==
ITGB1BP1 has been shown to [[Protein-protein interaction|interact]] with [[KRIT1]],<ref name=pmid11854171 /><ref name=pmid11741838>{{cite journal |last=Zhang |first=J |authorlink= |author2=Clatterbuck R E |author3=Rigamonti D |author4=Chang D D |author5=Dietz H C  |date=December 2001  |title=Interaction between krit1 and icap1alpha infers perturbation of integrin beta1-mediated angiogenesis in the pathogenesis of cerebral cavernous malformation |journal=Hum. Mol. Genet. |volume=10 |issue=25 |pages=2953–60 |publisher= |location = England| issn = 0964-6906| pmid = 11741838 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |doi=10.1093/hmg/10.25.2953 }}</ref> [[LRP2]],<ref name=pmid10827173>{{cite journal |last=Gotthardt |first=M |authorlink= |author2=Trommsdorff M |author3=Nevitt M F |author4=Shelton J |author5=Richardson J A |author6=Stockinger W |author7=Nimpf J |author8=Herz J  |date=August 2000  |title=Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction |journal=J. Biol. Chem. |volume=275 |issue=33 |pages=25616–24 |publisher= |location = UNITED STATES| issn = 0021-9258| pmid = 10827173 |doi = 10.1074/jbc.M000955200 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref> [[CD29]]<ref name=pmid9281591 /><ref name=pmid11741908>{{cite journal |last=Chang |first=David D |authorlink= |author2=Hoang Bao Q |author3=Liu Jenny |author4=Springer Timothy A  |date=March 2002  |title=Molecular basis for interaction between Icap1 alpha PTB domain and beta 1 integrin |journal=J. Biol. Chem. |volume=277 |issue=10 |pages=8140–5 |publisher= |location = United States| issn = 0021-9258| pmid = 11741908 |doi = 10.1074/jbc.M109031200 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref> and [[LRP1]].<ref name=pmid10827173/>


==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal | author=Andersson B, Wentland MA, Ricafrente JY, ''et al.'' |title=A "double adaptor" method for improved shotgun library construction. |journal=Anal. Biochem. |volume=236 |issue= 1 |pages= 107-13 |year= 1996 |pmid= 8619474 |doi= 10.1006/abio.1996.0138 }}
*{{cite journal   |vauthors=Andersson B, Wentland MA, Ricafrente JY, etal |title=A "double adaptor" method for improved shotgun library construction |journal=Anal. Biochem. |volume=236 |issue= 1 |pages= 107–13 |year= 1996 |pmid= 8619474 |doi= 10.1006/abio.1996.0138 }}
*{{cite journal | author=Yu W, Andersson B, Worley KC, ''et al.'' |title=Large-scale concatenation cDNA sequencing. |journal=Genome Res. |volume=7 |issue= 4 |pages= 353-8 |year= 1997 |pmid= 9110174 |doi=  }}
*{{cite journal   |vauthors=Yu W, Andersson B, Worley KC, etal |title=Large-scale concatenation cDNA sequencing |journal=Genome Res. |volume=7 |issue= 4 |pages= 353–8 |year= 1997 |pmid= 9110174 |doi= 10.1101/gr.7.4.353| pmc=139146 }}
*{{cite journal  | author=Chang DD, Wong C, Smith H, Liu J |title=ICAP-1, a novel beta1 integrin cytoplasmic domain-associated protein, binds to a conserved and functionally important NPXY sequence motif of beta1 integrin. |journal=J. Cell Biol. |volume=138 |issue= 5 |pages= 1149-57 |year= 1997 |pmid= 9281591 |doi= }}
*{{cite journal  |vauthors=Bouvard D, Block MR |title=Calcium/calmodulin-dependent protein kinase II controls integrin alpha5beta1-mediated cell adhesion through the integrin cytoplasmic domain associated protein-1alpha |journal=Biochem. Biophys. Res. Commun. |volume=252 |issue= 1 |pages= 46–50 |year= 1998 |pmid= 9813144 |doi= 10.1006/bbrc.1998.9592 }}
*{{cite journal | author=Bouvard D, Block MR |title=Calcium/calmodulin-dependent protein kinase II controls integrin alpha5beta1-mediated cell adhesion through the integrin cytoplasmic domain associated protein-1alpha. |journal=Biochem. Biophys. Res. Commun. |volume=252 |issue= 1 |pages= 46-50 |year= 1998 |pmid= 9813144 |doi= 10.1006/bbrc.1998.9592 }}
*{{cite journal   |vauthors=Gotthardt M, Trommsdorff M, Nevitt MF, etal |title=Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction |journal=J. Biol. Chem. |volume=275 |issue= 33 |pages= 25616–24 |year= 2000 |pmid= 10827173 |doi= 10.1074/jbc.M000955200 }}
*{{cite journal | author=Gotthardt M, Trommsdorff M, Nevitt MF, ''et al.'' |title=Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction. |journal=J. Biol. Chem. |volume=275 |issue= 33 |pages= 25616-24 |year= 2000 |pmid= 10827173 |doi= 10.1074/jbc.M000955200 }}
*{{cite journal   |vauthors=Zhang J, Clatterbuck RE, Rigamonti D, etal |title=Interaction between krit1 and icap1alpha infers perturbation of integrin beta1-mediated angiogenesis in the pathogenesis of cerebral cavernous malformation |journal=Hum. Mol. Genet. |volume=10 |issue= 25 |pages= 2953–60 |year= 2002 |pmid= 11741838 |doi=10.1093/hmg/10.25.2953  }}
*{{cite journal  | author=Zhang J, Clatterbuck RE, Rigamonti D, ''et al.'' |title=Interaction between krit1 and icap1alpha infers perturbation of integrin beta1-mediated angiogenesis in the pathogenesis of cerebral cavernous malformation. |journal=Hum. Mol. Genet. |volume=10 |issue= 25 |pages= 2953-60 |year= 2002 |pmid= 11741838 |doi= }}
*{{cite journal  |vauthors=Chang DD, Hoang BQ, Liu J, Springer TA |title=Molecular basis for interaction between Icap1 alpha PTB domain and beta 1 integrin |journal=J. Biol. Chem. |volume=277 |issue= 10 |pages= 8140–5 |year= 2002 |pmid= 11741908 |doi= 10.1074/jbc.M109031200 }}
*{{cite journal | author=Chang DD, Hoang BQ, Liu J, Springer TA |title=Molecular basis for interaction between Icap1 alpha PTB domain and beta 1 integrin. |journal=J. Biol. Chem. |volume=277 |issue= 10 |pages= 8140-5 |year= 2002 |pmid= 11741908 |doi= 10.1074/jbc.M109031200 }}
*{{cite journal   |vauthors=Fournier HN, Dupé-Manet S, Bouvard D, etal |title=Integrin cytoplasmic domain-associated protein 1alpha (ICAP-1alpha ) interacts directly with the metastasis suppressor nm23-H2, and both proteins are targeted to newly formed cell adhesion sites upon integrin engagement |journal=J. Biol. Chem. |volume=277 |issue= 23 |pages= 20895–902 |year= 2002 |pmid= 11919189 |doi= 10.1074/jbc.M200200200 }}
*{{cite journal | author=Zawistowski JS, Serebriiskii IG, Lee MF, ''et al.'' |title=KRIT1 association with the integrin-binding protein ICAP-1: a new direction in the elucidation of cerebral cavernous malformations (CCM1) pathogenesis. |journal=Hum. Mol. Genet. |volume=11 |issue= 4 |pages= 389-96 |year= 2002 |pmid= 11854171 |doi=  }}
*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |bibcode=2002PNAS...9916899M }}
*{{cite journal | author=Fournier HN, Dupé-Manet S, Bouvard D, ''et al.'' |title=Integrin cytoplasmic domain-associated protein 1alpha (ICAP-1alpha ) interacts directly with the metastasis suppressor nm23-H2, and both proteins are targeted to newly formed cell adhesion sites upon integrin engagement. |journal=J. Biol. Chem. |volume=277 |issue= 23 |pages= 20895-902 |year= 2002 |pmid= 11919189 |doi= 10.1074/jbc.M200200200 }}
*{{cite journal   |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  |vauthors=Hillman RT, Green RE, Brenner SE |title=An unappreciated role for RNA surveillance |journal=Genome Biol. |volume=5 |issue= 2 |pages= R8 |year= 2005 |pmid= 14759258 |doi= 10.1186/gb-2004-5-2-r8  | pmc=395752 }}
*{{cite journal | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal   |vauthors=Xia H, Nho RS, Kahm J, etal |title=Focal adhesion kinase is upstream of phosphatidylinositol 3-kinase/Akt in regulating fibroblast survival in response to contraction of type I collagen matrices via a beta 1 integrin viability signaling pathway |journal=J. Biol. Chem. |volume=279 |issue= 31 |pages= 33024–34 |year= 2004 |pmid= 15166238 |doi= 10.1074/jbc.M313265200 }}
*{{cite journal | author=Hillman RT, Green RE, Brenner SE |title=An unappreciated role for RNA surveillance. |journal=Genome Biol. |volume=5 |issue= 2 |pages= R8 |year= 2005 |pmid= 14759258 |doi= 10.1186/gb-2004-5-2-r8 }}
*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504  | pmc=528928 }}
*{{cite journal | author=Xia H, Nho RS, Kahm J, ''et al.'' |title=Focal adhesion kinase is upstream of phosphatidylinositol 3-kinase/Akt in regulating fibroblast survival in response to contraction of type I collagen matrices via a beta 1 integrin viability signaling pathway. |journal=J. Biol. Chem. |volume=279 |issue= 31 |pages= 33024-34 |year= 2004 |pmid= 15166238 |doi= 10.1074/jbc.M313265200 }}
*{{cite journal   |vauthors=Fournier HN, Dupé-Manet S, Bouvard D, etal |title=Nuclear translocation of integrin cytoplasmic domain-associated protein 1 stimulates cellular proliferation |journal=Mol. Biol. Cell |volume=16 |issue= 4 |pages= 1859–71 |year= 2005 |pmid= 15703214 |doi= 10.1091/mbc.E04-08-0744  | pmc=1073667 |hdl=2318/38098 }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal   |vauthors=Rual JF, Venkatesan K, Hao T, etal |title=Towards a proteome-scale map of the human protein-protein interaction network |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 |bibcode=2005Natur.437.1173R }}
*{{cite journal | author=Fournier HN, Dupé-Manet S, Bouvard D, ''et al.'' |title=Nuclear translocation of integrin cytoplasmic domain-associated protein 1 stimulates cellular proliferation. |journal=Mol. Biol. Cell |volume=16 |issue= 4 |pages= 1859-71 |year= 2005 |pmid= 15703214 |doi= 10.1091/mbc.E04-08-0744 }}
*{{cite journal   |vauthors=Oh JH, Yang JO, Hahn Y, etal |title=Transcriptome analysis of human gastric cancer |journal=Mamm. Genome |volume=16 |issue= 12 |pages= 942–54 |year= 2006 |pmid= 16341674 |doi= 10.1007/s00335-005-0075-2 }}
*{{cite journal | author=Rual JF, Venkatesan K, Hao T, ''et al.'' |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173-8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
*{{cite journal   |vauthors=Kimura K, Wakamatsu A, Suzuki Y, etal |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406 | pmc=1356129 }}
*{{cite journal | author=Oh JH, Yang JO, Hahn Y, ''et al.'' |title=Transcriptome analysis of human gastric cancer. |journal=Mamm. Genome |volume=16 |issue= 12 |pages= 942-54 |year= 2006 |pmid= 16341674 |doi= 10.1007/s00335-005-0075-2 }}
*{{cite journal   |vauthors=Stroeken PJ, Alvarez B, Van Rheenen J, etal |title=Integrin cytoplasmic domain-associated protein-1 (ICAP-1) interacts with the ROCK-I kinase at the plasma membrane |journal=J. Cell. Physiol. |volume=208 |issue= 3 |pages= 620–8 |year= 2006 |pmid= 16741948 |doi= 10.1002/jcp.20699 }}
*{{cite journal  | author=Kimura K, Wakamatsu A, Suzuki Y, ''et al.'' |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55-65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406 }}
*{{cite journal   |vauthors=Furusu A, Nakayama K, Xu Q, etal |title=MAP kinase-dependent, NF-kappaB-independent regulation of inhibitor of apoptosis protein genes by TNF-alpha |journal=J. Cell. Physiol. |volume=210 |issue= 3 |pages= 703–10 |year= 2007 |pmid= 17133355 |doi= 10.1002/jcp.20881 }}
*{{cite journal | author=Stroeken PJ, Alvarez B, Van Rheenen J, ''et al.'' |title=Integrin cytoplasmic domain-associated protein-1 (ICAP-1) interacts with the ROCK-I kinase at the plasma membrane. |journal=J. Cell. Physiol. |volume=208 |issue= 3 |pages= 620-8 |year= 2006 |pmid= 16741948 |doi= 10.1002/jcp.20699 }}
*{{cite journal | author=Furusu A, Nakayama K, Xu Q, ''et al.'' |title=MAP kinase-dependent, NF-kappaB-independent regulation of inhibitor of apoptosis protein genes by TNF-alpha. |journal=J. Cell. Physiol. |volume=210 |issue= 3 |pages= 703-10 |year= 2007 |pmid= 17133355 |doi= 10.1002/jcp.20881 }}
}}
}}
{{refend}}
{{refend}}


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Latest revision as of 14:15, 4 November 2018

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Integrin beta-1-binding protein 1 is a protein that in humans is encoded by the ITGB1BP1 gene.[1][2][3]

The cytoplasmic domains of integrins are essential for cell adhesion. The protein encoded by this gene binds to the beta1 integrin cytoplasmic domain. The interaction between this protein and beta1 integrin is highly specific. Two isoforms of this protein are derived from alternatively spliced transcripts. The shorter form of this protein does not interact with the beta1 integrin cytoplasmic domain. The longer form is a phosphoprotein and the extent of its phosphorylation is regulated by the cell-matrix interaction, suggesting an important role of this protein during integrin-dependent cell adhesion.[3]

Interactions

ITGB1BP1 has been shown to interact with KRIT1,[1][4] LRP2,[5] CD29[2][6] and LRP1.[5]

References

  1. ↑ 1.0 1.1 Zawistowski JS, Serebriiskii IG, Lee MF, Golemis EA, Marchuk DA (March 2002). "KRIT1 association with the integrin-binding protein ICAP-1: a new direction in the elucidation of cerebral cavernous malformations (CCM1) pathogenesis". Hum Mol Genet. 11 (4): 389–96. doi:10.1093/hmg/11.4.389. PMID 11854171.
  2. ↑ 2.0 2.1 Chang DD, Wong C, Smith H, Liu J (October 1997). "ICAP-1, a novel beta1 integrin cytoplasmic domain-associated protein, binds to a conserved and functionally important NPXY sequence motif of beta1 integrin". J Cell Biol. 138 (5): 1149–57. doi:10.1083/jcb.138.5.1149. PMC 2136751. PMID 9281591.
  3. ↑ 3.0 3.1 "Entrez Gene: ITGB1BP1 integrin beta 1 binding protein 1".
  4. ↑ Zhang, J; Clatterbuck R E; Rigamonti D; Chang D D; Dietz H C (December 2001). "Interaction between krit1 and icap1alpha infers perturbation of integrin beta1-mediated angiogenesis in the pathogenesis of cerebral cavernous malformation". Hum. Mol. Genet. England. 10 (25): 2953–60. doi:10.1093/hmg/10.25.2953. ISSN 0964-6906. PMID 11741838.
  5. ↑ 5.0 5.1 Gotthardt, M; Trommsdorff M; Nevitt M F; Shelton J; Richardson J A; Stockinger W; Nimpf J; Herz J (August 2000). "Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction". J. Biol. Chem. UNITED STATES. 275 (33): 25616–24. doi:10.1074/jbc.M000955200. ISSN 0021-9258. PMID 10827173.
  6. ↑ Chang, David D; Hoang Bao Q; Liu Jenny; Springer Timothy A (March 2002). "Molecular basis for interaction between Icap1 alpha PTB domain and beta 1 integrin". J. Biol. Chem. United States. 277 (10): 8140–5. doi:10.1074/jbc.M109031200. ISSN 0021-9258. PMID 11741908.

Further reading



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