Phosducin: Difference between revisions

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{{Infobox_gene}}
{{Infobox_gene}}
'''Phosducin''', also known as '''PDC''', is a human [[protein]] and [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: PDC phosducin| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5132| accessdate = }}</ref> It belongs to [[phosducin family]] of proteins.
'''Phosducin''', also known as '''PDC''', is a human [[protein]] and [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: PDC phosducin| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5132| accessdate = }}</ref> It belongs to the [[phosducin family]] of proteins.


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| summary_text = This gene encodes a phosphoprotein, which is located in the outer and inner segments of the rod cells in the [[retina]]. This protein may participate in the regulation of visual phototransduction or in the integration of photoreceptor metabolism. It modulates the phototransduction cascade by interacting with the beta and gamma subunits of the retinal G-protein transducin. By associating with these subunits only, the Transducin alpha subunit will remain active for longer. This will increase the amount of time of visual excitation.
| summary_text = This gene encodes a phosphoprotein, which is located in the outer and inner segments of the rod cells in the [[retina]]. This protein may participate in the regulation of visual phototransduction or in the integration of photoreceptor metabolism. It modulates the phototransduction cascade by interacting with the beta and gamma subunits of the retinal G-protein transducin. By associating with these subunits only, the Transducin alpha subunit will remain active for longer. This will increase the amount of time of visual excitation.


This gene is a potential candidate gene for retinitis pigmentosa and Usher syndrome type II. Alternatively spliced transcript variants encoding different isoforms have been identified.<ref name="entrez" />
This gene is a potential candidate gene for [[retinitis pigmentosa]] and [[Usher syndrome|Usher syndrome type II]]. Alternatively spliced transcript variants encoding different isoforms have been identified.<ref name="entrez" />
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Latest revision as of 05:06, 26 October 2018

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Phosducin, also known as PDC, is a human protein and gene.[1] It belongs to the phosducin family of proteins.

This gene encodes a phosphoprotein, which is located in the outer and inner segments of the rod cells in the retina. This protein may participate in the regulation of visual phototransduction or in the integration of photoreceptor metabolism. It modulates the phototransduction cascade by interacting with the beta and gamma subunits of the retinal G-protein transducin. By associating with these subunits only, the Transducin alpha subunit will remain active for longer. This will increase the amount of time of visual excitation.

This gene is a potential candidate gene for retinitis pigmentosa and Usher syndrome type II. Alternatively spliced transcript variants encoding different isoforms have been identified.[1]

See also

References

  1. ↑ 1.0 1.1 "Entrez Gene: PDC phosducin".

Further reading



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