RGS11: Difference between revisions

Jump to navigation Jump to search
m (Bot: HTTP→HTTPS)
 
m (1 revision imported)
 
(One intermediate revision by one other user not shown)
Line 1: Line 1:
{{Underlinked|date=June 2016}}
 
{{Infobox_gene}}
{{Infobox_gene}}
'''Regulator of G-protein signaling 11''' is a [[protein]] that in humans is encoded by the ''RGS11'' [[gene]].<ref name="pmid9789084">{{cite journal | vauthors = Snow BE, Krumins AM, Brothers GM, Lee SF, Wall MA, Chung S, Mangion J, Arya S, Gilman AG, Siderovski DP | title = A G protein gamma subunit-like domain shared between RGS11 and other RGS proteins specifies binding to Gbeta5 subunits | journal = Proc Natl Acad Sci U S A | volume = 95 | issue = 22 | pages = 13307–12 |date=Nov 1998 | pmid = 9789084 | pmc = 23793 | doi =10.1073/pnas.95.22.13307  }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: RGS11 regulator of G-protein signalling 11| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8786| accessdate = }}</ref>
'''Regulator of G-protein signaling 11''' is a [[protein]] that in humans is encoded by the ''RGS11'' [[gene]].<ref name="pmid9789084">{{cite journal | vauthors = Snow BE, Krumins AM, Brothers GM, Lee SF, Wall MA, Chung S, Mangion J, Arya S, Gilman AG, Siderovski DP | title = A G protein gamma subunit-like domain shared between RGS11 and other RGS proteins specifies binding to Gbeta5 subunits | journal = Proc Natl Acad Sci U S A | volume = 95 | issue = 22 | pages = 13307–12 |date=Nov 1998 | pmid = 9789084 | pmc = 23793 | doi =10.1073/pnas.95.22.13307  }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: RGS11 regulator of G-protein signalling 11| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8786| accessdate = }}</ref>
Line 6: Line 6:
{{PBB_Summary
{{PBB_Summary
| section_title =  
| section_title =  
| summary_text = The protein encoded by this gene belongs to the RGS (regulator of G protein signaling) family. Members of the RGS family act as GTPase-activating proteins on the alpha subunits of heterotrimeric, signal-transducing G proteins. This protein inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified.<ref name="entrez">{{cite web | title = Entrez Gene: RGS11 regulator of G-protein signalling 11| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8786| accessdate = }}</ref>
| summary_text = The protein encoded by this gene belongs to the RGS ([[regulator of G protein signaling]]) family. Members of the RGS family act as GTPase-activating proteins on the alpha subunits of heterotrimeric, signal-transducing [[G proteins]]. This protein inhibits signal transduction by increasing the [[GTPase]] activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Alternative splicing occurs at this locus and two transcript variants encoding distinct [[isoforms]] have been identified.<ref name="entrez">{{cite web | title = Entrez Gene: RGS11 regulator of G-protein signalling 11| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8786| accessdate = }}</ref>
}}
}}



Latest revision as of 09:22, 10 January 2019

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Regulator of G-protein signaling 11 is a protein that in humans is encoded by the RGS11 gene.[1][2]

The protein encoded by this gene belongs to the RGS (regulator of G protein signaling) family. Members of the RGS family act as GTPase-activating proteins on the alpha subunits of heterotrimeric, signal-transducing G proteins. This protein inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified.[2]

References

  1. Snow BE, Krumins AM, Brothers GM, Lee SF, Wall MA, Chung S, Mangion J, Arya S, Gilman AG, Siderovski DP (Nov 1998). "A G protein gamma subunit-like domain shared between RGS11 and other RGS proteins specifies binding to Gbeta5 subunits". Proc Natl Acad Sci U S A. 95 (22): 13307–12. doi:10.1073/pnas.95.22.13307. PMC 23793. PMID 9789084.
  2. 2.0 2.1 "Entrez Gene: RGS11 regulator of G-protein signalling 11".

Further reading