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| __NOTOC__
| | #Redirect[[Nephritic syndrome#Historical Perspective]] |
| {{Nephritic syndrome}}
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| ==Overview==
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| The symptoms of glomerulonephritis were first described by Richard Bright in 1827 when he discovered that several patients died with generalized edema were found to have renal disease.<ref>{{cite book | last = Bright | first = R | authorlink = | coauthors = | title = Reports of Medical Cases, Selected with a View of Illustrating the Symptoms and Cure of Diseases by a Reference to Morbid Anatomy, vol. I | publisher = Longmans | date = 1827-1831 | location = London | pages = | url = | doi = | id = | isbn = }}</ref> It was not until 1914 that Volhard and Fahr classified renal diseases in ''Die Brightsche Nierenkrankheit'' to 3 main categories: Nephroses, nephritis, and arteriosclerotic disease.<ref>{{cite book | last = Volhard | first = F | authorlink = | coauthors = | title = Die Brightsche Nierenkrankheit | publisher = Springer | date = 1914 | location = | pages = | url = | doi = | id = | isbn = }}</ref> Acute post-streptococcal glomerulonephritis is thus considered the earliest nephritic syndrome to be described. In 1908, C.F. Wahrer described an epidemic of hemorrhagic nephritis preceded by scarlet fever in 35 patients. Epidemics of nephritis continued in 1915 among British troops during World War I.<ref name="pmid13052693">{{cite journal| author=RAMMELKAMP CH, WEAVER RS| title=Acute glomerulonephritis, the significance of the variations in the incidence of the disease. | journal=J Clin Invest | year= 1953 |volume= 32 | issue= 4 | pages= 345-58 | pmid=13052693 | doi=10.1172/JCI102745 | pmc=PMC438348 |url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=13052693 }} </ref> Clinical and pathological findings from both epidemics were similar. Hemolytic streptococci were isolated from cultures of the oropharynx in many patients.<ref name="pmid13052693">{{cite journal| author=RAMMELKAMP CH, WEAVER RS| title=Acute glomerulonephritis, the significance of the variations in the incidence of the disease. | journal=J Clin Invest | year= 1953 | volume= 32 | issue= 4 | pages= 345-58 | pmid=13052693 |doi=10.1172/JCI102745 | pmc=PMC438348 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=13052693 }} </ref>
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| ==References==
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| {{reflist|2}}
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| {{WH}}
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| {{WS}}
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| [[Category:Disease]]
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| [[Category:Nephrology]]
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| [[Category:Syndromes]]
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| [[Category:Pediatrics]]
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