Sinusoidal obstruction syndrome classification: Difference between revisions

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Latest revision as of 15:23, 28 February 2018

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Husnain Shaukat, M.D [2]

Overview

There is no established system for the classification of sinusoidal obstruction syndrome. However, it can be classified on the basis of severity as mild, moderate and severe.

Classification

There is no established system for the classification of sinusoidal obstruction syndrome. However, it can be classified on the basis of severity as mild, moderate and severe.^[1]

Parameters	Mild	Moderate	Severe
Serum total bilirubin	<5 mg/dL	< (5.1 to 8 mg/dL	>8 mg/dL
Serum aspartate aminotransferase (AST)	<3 x normal	3 to 8 x normal	>8 x normal
Weight above baseline	<2 percent	2 to 5 percent	>5 percent
Serum creatinine	Normal	<2 x normal	>2 x normal
Rate of change	Slow (over 6–7 d)	(over 4–5 d)	Rapid (over2–3 d)

References

↑ Chao N (2014). "How I treat sinusoidal obstruction syndrome". Blood. 123 (26): 4023–6. doi:10.1182/blood-2014-03-551630. PMID 24833355.

Template:WS Template:WH

[pmid24833355-1] Chao N (2014). "How I treat sinusoidal obstruction syndrome". Blood. 123 (26): 4023–6. doi:10.1182/blood-2014-03-551630. PMID 24833355.

[1]

@@ Line 1: / Line 1: @@
 __NOTOC__
 {{Sinusoidal obstruction syndrome}}
-{{CMG}}; {{AE}}
+{{CMG}}; {{AE}} {{HS}}
 ==Overview==
-There is no established system for the classification of sinusoidal obstruction syndrome.
+There is no established system for the classification of sinusoidal obstruction syndrome. However, it can be classified on the basis of severity as mild, moderate and severe.
 ==Classification==
-There is no established system for the classification of sinusoidal obstruction syndrome. However, it can be classified on the basis of severity as mild, moderate and sever.
+There is no established system for the classification of sinusoidal obstruction syndrome. However, it can be classified on the basis of severity as mild, moderate and severe.<ref name="pmid24833355">{{cite journal |vauthors=Chao N |title=How I treat sinusoidal obstruction syndrome |journal=Blood |volume=123 |issue=26 |pages=4023–6 |year=2014 |pmid=24833355 |doi=10.1182/blood-2014-03-551630 |url=}}</ref>
 {| class="wikitable"
@@ Line 15: / Line 15: @@
 ! colspan="1" rowspan="1" align="center" style="background:#4479BA; color: #FFFFFF;" + |Severe
 |-
-| align="center" style="background:#DCDCDC;" + |Serum total bilirubin
+| align="center" style="background:#DCDCDC;" + |Serum [[Bilirubin|total bilirubin]]
 |
 * <5 mg/dL
@@ Line 23: / Line 23: @@
 * >8 mg/dL
 |-
-| align="center" style="background:#DCDCDC;" + |Serum aspartate aminotransferase (AST)
+| align="center" style="background:#DCDCDC;" + |[[AST|Serum aspartate aminotransferase (AST)]]
 |
 * <3 x normal
+|
+* 3 to 8 x normal
 |
 * >8 x normal
-|
-* 3 to 8 x normal
 |-
 | colspan="1" rowspan="1" align="center" style="background:#DCDCDC;" + |[[Anion gap|Weight above baseline]]
 | colspan="1" rowspan="1" |
-* (Na<sup>+</sup>) – (Cl<sup>–</sup> + HCO3<sup>–</sup>)
+* <2 percent
 | colspan="1" rowspan="1" |
-* 7 to 13 (mEq/L)
+* 2 to 5 percent
 |
-* Variable
+* >5 percent
 |-
 | colspan="1" rowspan="1" align="center" style="background:#DCDCDC;" + |[[Osmolality|Serum creatinine]]
 | colspan="1" rowspan="1" |
-* 2([[Sodium|Na]] + [[Potassium|K]]) + ([[glucose]]/18) + ([[blood]] [[urea]] [[nitrogen]]/2.8)
+* Normal
 | colspan="1" rowspan="1" |
-* 285 to 295 mOsm/kg (285 to 295 mmol/kg) of water
+* <2 x normal
 |
-* Increased (> 320mOsm/kg)
+* >2 x normal
+|-
+|Rate of change
+|Slow (over 6–7 d)
+|(over 4–5 d)
+|Rapid (over2–3 d)
 |}

Sinusoidal obstruction syndrome classification: Difference between revisions

Latest revision as of 15:23, 28 February 2018

Overview

Classification

References

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