SRXN1: Difference between revisions

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Identifiers
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External IDs	GeneCards: [1]
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Revision as of 06:59, 11 September 2017

Sulfiredoxin-1 is a protein that in humans is encoded by the SRXN1 gene.^[1]

References

↑ "Entrez Gene: SRXN1 sulfiredoxin 1 homolog (S. Cerevisiae)".

Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
Venter JC, Adams MD, Myers EW, et al. (2001). "The sequence of the human genome". Science. 291 (5507): 1304–51. doi:10.1126/science.1058040. PMID 11181995.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
Deloukas P, Matthews LH, Ashurst J, et al. (2002). "The DNA sequence and comparative analysis of human chromosome 20". Nature. 414 (6866): 865–71. doi:10.1038/414865a. PMID 11780052.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Chang TS, Jeong W, Woo HA, et al. (2005). "Characterization of mammalian sulfiredoxin and its reactivation of hyperoxidized peroxiredoxin through reduction of cysteine sulfinic acid in the active site to cysteine". J. Biol. Chem. 279 (49): 50994–1001. doi:10.1074/jbc.M409482200. PMID 15448164.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
Woo HA, Jeong W, Chang TS, et al. (2005). "Reduction of cysteine sulfinic acid by sulfiredoxin is specific to 2-cys peroxiredoxins". J. Biol. Chem. 280 (5): 3125–8. doi:10.1074/jbc.C400496200. PMID 15590625.
Jönsson TJ, Murray MS, Johnson LC, et al. (2005). "Structural basis for the retroreduction of inactivated peroxiredoxins by human sulfiredoxin". Biochemistry. 44 (24): 8634–42. doi:10.1021/bi050131i. PMID 15952770.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
Jeong W, Park SJ, Chang TS, et al. (2006). "Molecular mechanism of the reduction of cysteine sulfinic acid of peroxiredoxin to cysteine by mammalian sulfiredoxin". J. Biol. Chem. 281 (20): 14400–7. doi:10.1074/jbc.M511082200. PMID 16565085.
Findlay VJ, Townsend DM, Morris TE, et al. (2006). "A novel role for human sulfiredoxin in the reversal of glutathionylation". Cancer Res. 66 (13): 6800–6. doi:10.1158/0008-5472.CAN-06-0484. PMID 16818657.

This protein-related article is a stub. You can help Wikipedia by expanding it.

[entrez-1] "Entrez Gene: SRXN1 sulfiredoxin 1 homolog (S. Cerevisiae)".

[1]

@@ Line 1: / Line 1: @@
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+{{Underlinked|date=June 2016}}
-{{PBB_Controls
+{{Infobox_gene}}
-| update_page = yes
+'''Sulfiredoxin-1''' is a [[protein]] that in humans is encoded by the ''SRXN1'' [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: SRXN1 sulfiredoxin 1 homolog (S. Cerevisiae)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=140809| accessdate = }}</ref>
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-{{GNF_Protein_box
- | image = PBB_Protein_SRXN1_image.jpg
- | image_source = [[Protein_Data_Bank|PDB]] rendering based on 1xw3.
- | PDB = {{PDB2|1xw3}}, {{PDB2|1xw4}}, {{PDB2|1yzs}}, {{PDB2|2b6f}}
- | Name = Sulfiredoxin 1 homolog (S. cerevisiae)
- | HGNCid = 16132
- | Symbol = SRXN1
- | AltSymbols =; C20orf139; Npn3; SRX1; YKL086W; dJ850E9.2
- | OMIM =
- | ECnumber =
- | Homologene = 32722
- | MGIid = 104971
- | Function = {{GNF_GO|id=GO:0000166 |text = nucleotide binding}} {{GNF_GO|id=GO:0000287 |text = magnesium ion binding}} {{GNF_GO|id=GO:0005524 |text = ATP binding}} {{GNF_GO|id=GO:0016209 |text = antioxidant activity}} {{GNF_GO|id=GO:0016667 |text = oxidoreductase activity, acting on sulfur group of donors}}
- | Component = {{GNF_GO|id=GO:0005829 |text = cytosol}}
- | Process = {{GNF_GO|id=GO:0006979 |text = response to oxidative stress}}
- | Orthologs = {{GNF_Ortholog_box
-    | Hs_EntrezGene = 140809
-    | Hs_Ensembl =
-    | Hs_RefseqProtein = NP_542763
-    | Hs_RefseqmRNA = NM_080725
-    | Hs_GenLoc_db =
-    | Hs_GenLoc_chr =
-    | Hs_GenLoc_start =
-    | Hs_GenLoc_end =
-    | Hs_Uniprot =
-    | Mm_EntrezGene = 76650
-    | Mm_Ensembl = ENSMUSG00000032802
-    | Mm_RefseqmRNA = NM_029688
-    | Mm_RefseqProtein = NP_083964
-    | Mm_GenLoc_db =
-    | Mm_GenLoc_chr = 2
-    | Mm_GenLoc_start = 151796965
-    | Mm_GenLoc_end = 151802030
-    | Mm_Uniprot = Q9D975
-  }}
-}}
-'''Sulfiredoxin 1 homolog (S. cerevisiae)''', also known as '''SRXN1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: SRXN1 sulfiredoxin 1 homolog (S. cerevisiae)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=140809| accessdate = }}</ref>
 <!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
@@ Line 54: / Line 10: @@
 ==References==
-{{reflist|2}}
+{{reflist}}
 ==Further reading==
 {{refbegin | 2}}
 {{PBB_Further_reading
 | citations =
-*{{cite journal  | author=Hartley JL, Temple GF, Brasch MA |title=DNA cloning using in vitro site-specific recombination. |journal=Genome Res. |volume=10 |issue= 11 |pages= 1788-95 |year= 2001 |pmid= 11076863 |doi=  }}
+*{{cite journal  | vauthors=Hartley JL, Temple GF, Brasch MA |title=DNA cloning using in vitro site-specific recombination |journal=Genome Res. |volume=10 |issue= 11 |pages= 1788–95 |year= 2001 |pmid= 11076863 |doi=10.1101/gr.143000  | pmc=310948  }}
-*{{cite journal  | author=Venter JC, Adams MD, Myers EW, ''et al.'' |title=The sequence of the human genome. |journal=Science |volume=291 |issue= 5507 |pages= 1304-51 |year= 2001 |pmid= 11181995 |doi= 10.1126/science.1058040 }}
+*{{cite journal   |vauthors=Venter JC, Adams MD, Myers EW, etal |title=The sequence of the human genome |journal=Science |volume=291 |issue= 5507 |pages= 1304–51 |year= 2001 |pmid= 11181995 |doi= 10.1126/science.1058040 }}
-*{{cite journal  | author=Wiemann S, Weil B, Wellenreuther R, ''et al.'' |title=Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. |journal=Genome Res. |volume=11 |issue= 3 |pages= 422-35 |year= 2001 |pmid= 11230166 |doi= 10.1101/gr.154701 }}
+*{{cite journal   |vauthors=Wiemann S, Weil B, Wellenreuther R, etal |title=Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs |journal=Genome Res. |volume=11 |issue= 3 |pages= 422–35 |year= 2001 |pmid= 11230166 |doi= 10.1101/gr.GR1547R  | pmc=311072 }}
-*{{cite journal  | author=Deloukas P, Matthews LH, Ashurst J, ''et al.'' |title=The DNA sequence and comparative analysis of human chromosome 20. |journal=Nature |volume=414 |issue= 6866 |pages= 865-71 |year= 2002 |pmid= 11780052 |doi= 10.1038/414865a }}
+*{{cite journal   |vauthors=Deloukas P, Matthews LH, Ashurst J, etal |title=The DNA sequence and comparative analysis of human chromosome 20 |journal=Nature |volume=414 |issue= 6866 |pages= 865–71 |year= 2002 |pmid= 11780052 |doi= 10.1038/414865a }}
-*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
+*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 }}
-*{{cite journal  | author=Chang TS, Jeong W, Woo HA, ''et al.'' |title=Characterization of mammalian sulfiredoxin and its reactivation of hyperoxidized peroxiredoxin through reduction of cysteine sulfinic acid in the active site to cysteine. |journal=J. Biol. Chem. |volume=279 |issue= 49 |pages= 50994-1001 |year= 2005 |pmid= 15448164 |doi= 10.1074/jbc.M409482200 }}
+*{{cite journal   |vauthors=Chang TS, Jeong W, Woo HA, etal |title=Characterization of mammalian sulfiredoxin and its reactivation of hyperoxidized peroxiredoxin through reduction of cysteine sulfinic acid in the active site to cysteine |journal=J. Biol. Chem. |volume=279 |issue= 49 |pages= 50994–1001 |year= 2005 |pmid= 15448164 |doi= 10.1074/jbc.M409482200 }}
-*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
+*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504  | pmc=528928 }}
-*{{cite journal  | author=Wiemann S, Arlt D, Huber W, ''et al.'' |title=From ORFeome to biology: a functional genomics pipeline. |journal=Genome Res. |volume=14 |issue= 10B |pages= 2136-44 |year= 2004 |pmid= 15489336 |doi= 10.1101/gr.2576704 }}
+*{{cite journal   |vauthors=Wiemann S, Arlt D, Huber W, etal |title=From ORFeome to biology: a functional genomics pipeline |journal=Genome Res. |volume=14 |issue= 10B |pages= 2136–44 |year= 2004 |pmid= 15489336 |doi= 10.1101/gr.2576704  | pmc=528930 }}
-*{{cite journal  | author=Woo HA, Jeong W, Chang TS, ''et al.'' |title=Reduction of cysteine sulfinic acid by sulfiredoxin is specific to 2-cys peroxiredoxins. |journal=J. Biol. Chem. |volume=280 |issue= 5 |pages= 3125-8 |year= 2005 |pmid= 15590625 |doi= 10.1074/jbc.C400496200 }}
+*{{cite journal   |vauthors=Woo HA, Jeong W, Chang TS, etal |title=Reduction of cysteine sulfinic acid by sulfiredoxin is specific to 2-cys peroxiredoxins |journal=J. Biol. Chem. |volume=280 |issue= 5 |pages= 3125–8 |year= 2005 |pmid= 15590625 |doi= 10.1074/jbc.C400496200 }}
-*{{cite journal  | author=Jönsson TJ, Murray MS, Johnson LC, ''et al.'' |title=Structural basis for the retroreduction of inactivated peroxiredoxins by human sulfiredoxin. |journal=Biochemistry |volume=44 |issue= 24 |pages= 8634-42 |year= 2005 |pmid= 15952770 |doi= 10.1021/bi050131i }}
+*{{cite journal   |vauthors=Jönsson TJ, Murray MS, Johnson LC, etal |title=Structural basis for the retroreduction of inactivated peroxiredoxins by human sulfiredoxin |journal=Biochemistry |volume=44 |issue= 24 |pages= 8634–42 |year= 2005 |pmid= 15952770 |doi= 10.1021/bi050131i }}
-*{{cite journal  | author=Mehrle A, Rosenfelder H, Schupp I, ''et al.'' |title=The LIFEdb database in 2006. |journal=Nucleic Acids Res. |volume=34 |issue= Database issue |pages= D415-8 |year= 2006 |pmid= 16381901 |doi= 10.1093/nar/gkj139 }}
+*{{cite journal   |vauthors=Mehrle A, Rosenfelder H, Schupp I, etal |title=The LIFEdb database in 2006 |journal=Nucleic Acids Res. |volume=34 |issue= Database issue |pages= D415–8 |year= 2006 |pmid= 16381901 |doi= 10.1093/nar/gkj139  | pmc=1347501 }}
-*{{cite journal  | author=Jeong W, Park SJ, Chang TS, ''et al.'' |title=Molecular mechanism of the reduction of cysteine sulfinic acid of peroxiredoxin to cysteine by mammalian sulfiredoxin. |journal=J. Biol. Chem. |volume=281 |issue= 20 |pages= 14400-7 |year= 2006 |pmid= 16565085 |doi= 10.1074/jbc.M511082200 }}
+*{{cite journal   |vauthors=Jeong W, Park SJ, Chang TS, etal |title=Molecular mechanism of the reduction of cysteine sulfinic acid of peroxiredoxin to cysteine by mammalian sulfiredoxin |journal=J. Biol. Chem. |volume=281 |issue= 20 |pages= 14400–7 |year= 2006 |pmid= 16565085 |doi= 10.1074/jbc.M511082200 }}
-*{{cite journal  | author=Findlay VJ, Townsend DM, Morris TE, ''et al.'' |title=A novel role for human sulfiredoxin in the reversal of glutathionylation. |journal=Cancer Res. |volume=66 |issue= 13 |pages= 6800-6 |year= 2006 |pmid= 16818657 |doi= 10.1158/0008-5472.CAN-06-0484 }}
+*{{cite journal   |vauthors=Findlay VJ, Townsend DM, Morris TE, etal |title=A novel role for human sulfiredoxin in the reversal of glutathionylation |journal=Cancer Res. |volume=66 |issue= 13 |pages= 6800–6 |year= 2006 |pmid= 16818657 |doi= 10.1158/0008-5472.CAN-06-0484 }}
 }}
 {{refend}}
+{{PDB Gallery|geneid=140809}}
+<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
+{{PBB_Controls
+| update_page = yes
+| require_manual_inspection = no
+| update_protein_box = yes
+| update_summary = yes
+| update_citations = yes
+}}
 {{protein-stub}}
-{{WikiDoc Sources}}

SRXN1: Difference between revisions

Revision as of 06:59, 11 September 2017

References

Further reading

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